Pathogenesis of hepatitis B virus—related hepatocellular carcinoma: Old and new paradigms

Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

2003 • 837 citations

Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: Clinically significant or purely “occult”?

2001 • 559 citations

Occult hepatitis B

2002 • 524 citations

Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection

2003 • 416 citations

Calcium Signaling by HBx Protein in Hepatitis B Virus DNA Replication

2001 • 382 citations

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene

2003 • 308 citations

Hepatitis B Virus X Protein Colocalizes to Mitochondria with a Human Voltage-Dependent Anion Channel, HVDAC3, and Alters Its Transmembrane Potential

2000 • 306 citations

Viruses, Immunity, and Cancer: Lessons from Hepatitis B

2000 • 294 citations

Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)

2000 • 270 citations

Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues.

2001 • 186 citations

Preferential integration of human papillomavirus type 18 near the c-myc locus in cervical carcinoma

2003 • 180 citations

Antibodies to Peptides Detect New Hepatitis B Antigen: Serological Correlation with Hepatocellular Carcinoma

1985 • 169 citations

Specific mutations of hepatitis B virus in plasma predict liver cancer development

2004 • 162 citations

Hepadnaviral X protein: Review of recent progress

1996 • 161 citations

In vivo expression of a new hepatitis B virus protein encoded by a spliced RNA

2000 • 146 citations

Src kinases involved in hepatitis B virus replication

1999 • 118 citations

Cloning and Characterization of a Novel Human Hepatocyte Transcription Factor, hB1F, Which Binds and Activates Enhancer II of Hepatitis B Virus

1998 • 113 citations

Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen

2003 • 111 citations

Caspase-dependent Alterations of Ca2+ Signaling in the Induction of Apoptosis by Hepatitis B Virus X Protein

2003 • 108 citations

The expression of hepatitis B spliced protein (HBSP) encoded by a spliced hepatitis B virus RNA is associated with viral replication and liver fibrosis

2003 • 106 citations

Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation

2002 • 99 citations

cis-Activation of the Human Telomerase Gene (hTERT) by the Hepatitis B Virus Genome

2001 • 90 citations

Detection of the Hepatitis B Virus X Protein (HBx) Antigen and Anti-HBx Antibodies in Cases of Human Hepatocellular Carcinoma

2003 • 79 citations

Precore and core promoter mutations, hepatitis B virus DNA levels and progressive liver injury in chronic hepatitis B

2002 • 75 citations

Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection

2003 • 74 citations

Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: An alternative mechanism of HBx-related pathogenesis

2002 • 71 citations

Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors

2004 • 54 citations

Sequences of Hepatitis B Virus DNA in the Serum and Liver of Patients with Acute Benign and Fulminant Hepatitis

1987 • 53 citations

Molecular cloning of a rat chromosome putative recombinogenic sequence homologous to the hepatitis B virus encapsidation signal.

1996 • 39 citations

An association between viral genes and human oncogenic alterations: The adenovirus E1A induces the Ewing tumor fusion transcript EWS–FLI1

1999 • 38 citations

Antisense Downregulation of N- myc1 in Woodchuck Hepatoma Cells Reverses the Malignant Phenotype

1998 • 18 citations

The hepatitis C virus (HCV) induces a long-term increase in interleukin-10 production by human CD4+ T cells (H9).

2001 • 13 citations

Viruses, Immunity, and Cancer

1985 • 3 citations