PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

Insulin-promoter-factor 1 is required for pancreas development in mice

1994 • 1,789 citations

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1996 • 1,505 citations

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

1997 • 1,107 citations

β-Cell-specific inactivation of the mouseIpf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes

1998 • 901 citations

IPF1, a homeodomain-containing transactivator of the insulin gene.

1993 • 882 citations

Expression of murine STF-1, a putative insulin gene transcription factor, in β cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny

1995 • 562 citations

Nuclear Translocation of Extradenticle Requires , which Encodes an Extradenticle-Related Homeodomain Protein

1997 • 440 citations

IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene.

1994 • 427 citations

The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration.

1999 • 339 citations

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.

1993 • 332 citations

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor.

1996 • 328 citations

Hepatocyte Nuclear Factor 3β is Involved in Pancreatic β-Cell-Specific Transcription of the pdx-1 Gene

1997 • 256 citations

Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

1994 • 205 citations

PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin

1996 • 202 citations

Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor α

1999 • 201 citations

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

1998 • 170 citations

The Pancreatic Islet Factor STF-1 Binds Cooperatively with Pbx to a Regulatory Element in the Somatostatin Promoter: Importance of the FPWMK Motif and of the Homeodomain

1995 • 152 citations

Pbx-Hox Heterodimers Recruit Coactivator-Corepressor Complexes in an Isoform-Specific Manner

1999 • 150 citations

XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor.

1994 • 141 citations

Hoxa9 Immortalizes a Granulocyte-Macrophage Colony-Stimulating Factor-Dependent Promyelocyte Capable of Biphenotypic Differentiation to Neutrophils or Macrophages, Independent of Enforced Meis Expression

2000 • 131 citations

PDX-1 and Msx-2 expression in the regenerating and developing pancreas

1999 • 98 citations

Pancreatic Islet Expression of the Homeobox Factor STF-1 Relies on an E-box Motif That Binds USF

1996 • 88 citations

The Labeling of Proliferating Cells by Ki67 and MIB-1 Antibodies Depends on the Binding of a Nuclear Protein to the DNA

1994 • 62 citations