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Sequestration of Tubulin in Neurons in Alzheimer's disease

Data up to Jan 2025

Published1986
Citations53
References36

Total Citations Per Year

Abstract

References (36)

Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation

1984 • 2,199 citations

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ.

1983 • 1,162 citations

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

1985 • 1,025 citations

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

1963 • 956 citations

Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia

1977 • 628 citations

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants

1982 • 541 citations

Alzheimer's Disease: Insolubility of Partially Purified Paired Helical Filaments in Sodium Dodecyl Sulfate and Urea

1982 • 398 citations

Alzheimer's Neurofibrillary Changes

1962 • 396 citations

New Perspectives on Alzheimer's Disease

1986 • 349 citations

Slow Axonal Transport of Neurofilament Proteins: Impairment of β,β′-Iminodipropionitrile Administration

1978 • 340 citations

Aberrant neurofilament phosphorylation in Alzheimer disease.

1985 • 339 citations

The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies and "rod-like" structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex.

1968 • 298 citations

THE FINE STRUCTURE OF SOME INTRAGANGLIONIC ALTERATIONS

1968 • 239 citations

Subunit structure of paired helical filaments in Alzheimer's disease.

1985 • 224 citations

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.

1985 • 220 citations

Neuritic plaques in senile dementia of Alzheimer type: a Golgi analysis in the hippocampal region

1983 • 194 citations

Phosphorylated Neurofilament Antigens in Neurofibrillary Tangles in Alzheimerʼs Disease

1986 • 158 citations

Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type

1985 • 157 citations

Ultrastructure of Paired Helical Filaments of Alzheimerʼs Neurofibrillary Tangle

1984 • 128 citations

Granulovacuolar degeneration of hippocampal pyramidal cells

1972 • 125 citations

The Association of Actin with Hirano Bodies

1983 • 112 citations

GRANULOVACUOLAR DEGENERATION IN THE AGEING BRAIN AND IN DEMENTIA

1977 • 107 citations

Neurofibrillary Changes in Human Brain

1983 • 103 citations

Reorganization of axoplasmic organelles following beta, beta'-iminodipropionitrile administration.

1981 • 99 citations

Microtubule-associated protein tau (? ) is a major antigenic component of paired helical filaments in Alzheimer disease

1987 • 99 citations

Microtubule-neurofilament segregation produced by beta, beta'- iminodipropionitrile: evidence for the association of fast axonal transport with microtubules

1983 • 92 citations

Cytoskeletal disorganization induced by local application of β,β′‐iminodipropionitrile and 2,5‐hexanedione

1983 • 77 citations

Alzheimer's disease: Immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies

1984 • 76 citations

Isolation of microtubule protein from chicken erythrocytes and determination of the critical concentration for tubulin polymerization in vitro and in vivo.

1983 • 74 citations

Cellular pathology in Alzheimer's and Parkinson's diseases

1986 • 71 citations

Staining of Alzheimer's neurofibrillary tangles with antiserum against 200K component of neurofilament.

1981 • 55 citations

Senile cerebral disease: a critical survey of traditional concepts based upon observations with newer technics.

1959 • 39 citations

Neurotoxic probes of the axonal cytoskeleton

1983 • 36 citations

[37] Isolation of paired helical filaments and amyloid fibers from human brain

1986 • 24 citations

The pattern of MAP-2 binding on microtubules: visual enhancement of MAP attachment sites by antibody labeling and electron microscopy

1983 • 13 citations

Structural Proteins in Alzheimer’s Disease

1986 • 1 citations

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Sequestration of Tubulin in Neurons in Alzheimer's disease (1986) – Brain Research | Metascience Observatory Explorer