Structural Proteins in Alzheimer’s Disease

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Observations on the brains of demented old people

1970 • 2,066 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

1963 • 956 citations

ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

1964 • 646 citations

Plaques, tangles and dementia

1982 • 603 citations

X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.

1986 • 553 citations

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants

1982 • 541 citations

Alzheimer's Disease: Insolubility of Partially Purified Paired Helical Filaments in Sodium Dodecyl Sulfate and Urea

1982 • 398 citations

Neurofibrillary tangles of paired helical filaments

1976 • 366 citations

Aging of the brain and dementia

1980 • 259 citations

Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins

1983 • 252 citations

Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.

1984 • 227 citations

Alzheimer paired helical filaments: Bulk isolation, solubility, and protein composition

1984 • 227 citations

Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers.

1982 • 219 citations

Biological Aspects of Alzheimer's Disease

1984 • 203 citations

Neurofibrillary tangles of Alzheimer's disease: an immunohistochemical study.

1985 • 201 citations

The Contribution of Altered Synapses in the Senile Plaque: An Electron Microscopic Study in Alzheimer's Dementia^*†

1967 • 179 citations

EVIDENCE THAT ALZHEIMER NEUROFIBRILLARY TANGLES ORIGINATE FROM NEUROTUBULES

1979 • 125 citations

Protein changes in senile dementia

1974 • 117 citations

Reappraisal of the fine structure of Alzheimer's neurofibrillary tangles

1981 • 109 citations

Alzheimer neurofibrillary tangles: Monoclonal antibodies to inherent antigen(s)

1984 • 106 citations

Immunostaining of neurofibrillary tangles in Alzheimer's senile dementia with a neurofilament antiserum

1982 • 97 citations

Organization of the neurofilamentous network

1981 • 91 citations

NEUROFIBRILLARY TANGLES AND THE PATHOGENESIS OF DEMENTIA: A QUANTITATIVE STUDY

1976 • 90 citations

Posttraumatic Premature Alzheimer's Disease

1982 • 89 citations

Neurofibrillary tangles in senile dementia of the Alzheimer type share an antigenic determinant with intermediate filaments of the vimentin class.

1983 • 85 citations

Immunocytochemical studies of neurofibrillary tangles.

1981 • 78 citations

Alzheimer's disease: Immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies

1984 • 76 citations

Electron microscopic structure of the alzheimer's neurofibrillary changes in case of atypical senile dementia

1978 • 56 citations

Staining of Alzheimer's neurofibrillary tangles with antiserum against 200K component of neurofilament.

1981 • 55 citations

Alzheimer neurofibrillary tangles: Antiserum and immunohistological staining

1979 • 51 citations

Ageing of the brain and dementia

1980 • 46 citations

LOSS OF LARGE NEURONS OF THE MEDIAL SEPTAL NUCLEUS IN AN AUTOPSY CASE OF ALZHEIMERʼS DISEASE

1982 • 40 citations

Alzheimer's disease: exposure of neurofilament immunoreactivity in SDS-insoluble paired helical filaments

1984 • 30 citations

Ageing of the brain and dementia

1980 • 21 citations

Intermediate Filaments

1985 • 20 citations

Paired Helical Filaments in Human Neurons: Relationship to Neurofilaments

1985 • 6 citations

Production and Characterization of Monoclonal Antibodies to Alzheimer Paired Helical Filaments

1985 • 6 citations

Biochemical and Structural Studies of Paired Helical Filaments and Senile Plaque Amyloid in Alzheimer’s Disease

1986 • 2 citations