Plasminogen interacts with human platelets through two distinct mechanisms.

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

A Method of Trace Iodination of Proteins for Immunologic Studies

1966 • 2,148 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

1983 • 780 citations

Isolation and characterization of alpha2-plasmin inhibitor from human plasma. A novel proteinase inhibitor which inhibits activator-induced clot lysis.

1976 • 474 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.

1980 • 373 citations

Interrelations of Platelet Aggregation and Secretion

1977 • 350 citations

Sequencing of Proteins and Peptides

1981 • 338 citations

Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex.

1982 • 337 citations

The binding of human plasminogen to fibrin and fibrinogen.

1983 • 321 citations

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

1983 • 315 citations

Binding and activation of plasminogen on the platelet surface.

1985 • 312 citations

Biochemical studies of two patients with the gray platelet syndrome. Selective deficiency of platelet alpha granules.

1980 • 293 citations

Isolation and characterization of a human plasma protein with affinity for the lysine binding sites in plasminogen. Role in the regulation of fibrinolysis and identification as histidine-rich glycoprotein.

1980 • 289 citations

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

1983 • 280 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis

1981 • 261 citations

Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies.

1983 • 241 citations

Characterization of human plasminogen II. Separation and partial characterization of different molecular forms of human plasminogen

1972 • 241 citations

Purification and Characterization of Human Antiplasmin, the Fast-Acting Plasmin Inhibitor in Plasma

1977 • 228 citations

Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions

1985 • 209 citations

Amino acid sequence studies on artiodactyl fibrinopeptides

1967 • 197 citations

Additional glycoprotein defects in Bernard-Soulier's syndrome: confirmation of genetic basis by parental analysis

1983 • 186 citations

Reduced surface expression and binding of fibronectin by thrombin-stimulated thrombasthenic platelets.

1983 • 168 citations

Complex formation of platelet thrombospondin with plasminogen. Modulation of activation by tissue activator.

1984 • 164 citations

Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets.

1980 • 163 citations

Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

1981 • 151 citations

Effects of chymotrypsin and adenosine diphosphate on the exposure of fibrinogen receptors on normal human and Glanzmann's thrombasthenic platelets.

1981 • 144 citations

Calcium cation regulation of glycoprotein IIb-IIIa complex formation in platelet plasma membranes.

1983 • 144 citations

Histidine-rich glycoprotein is present in human platelets and is released following thrombin stimulation

1983 • 127 citations

[22] Plasminogen and plasmin

1976 • 117 citations

The presence and release of alpha 2-antiplasmin from human platelets

1981 • 114 citations

Effect of calcium on the stability of the platelet membrane glycoprotein IIb-IIIa complex.

1985 • 105 citations

Binding of radioiodinated human von Willebrand factor to Bernard-Soulier, thrombasthenic and von Willebrand's disease platelets

1980 • 96 citations

Participation of ADP in the binding of fibrinogen to thrombin- stimulated platelets

1980 • 86 citations

Studies on platelet plasma membranes. IV. Quantitative analysis of platelet membrane glycoproteins by (125I)-diazotized diiodosulfanilic acid labeling and SDS-polyacrylamide gel electrophoresis.

1978 • 76 citations

Biochemical and functional consequences of dissociation of the platelet membrane glycoprotein IIb-IIIa complex

1985 • 74 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 62 citations

Role of Platelet Fibrinogen in the Reactions of Platelets to Thrombin*

1965 • 51 citations

The interaction of fibrinogen with human platelets in a plasma milieu

1982 • 49 citations

Fibronectin expression on the platelet surface occurs in concert with secretion

1981 • 45 citations

Human platelet fibrinogen: purification and hemostatic properties

1985 • 38 citations

Fibronectin binding to thrombin-stimulated platelets: evidence for fibrin(ogen) independent and dependent pathways

1985 • 37 citations

Binding of fibronectin to alpha-granule-deficient platelets.

1983 • 34 citations

Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions

1985 • 30 citations

Platelets and Fibrinolysis

1977 • 22 citations

Histidine-rich glycoprotein is present in human platelets and is released following thrombin stimulation

1983 • 21 citations

Unique immunochemical features and intracellular stability of platelet fibrinogen

1975 • 20 citations

Isoelectric characteristics and surface radioiodination of normal and thrombasthenic platelet membrane glycoproteins

1981 • 17 citations

Additional glycoprotein defects in Bernard-Soulier's syndrome: confirmation of genetic basis by parental analysis

1983 • 16 citations

Participation of ADP in the binding of fibrinogen to thrombin- stimulated platelets

1980 • 11 citations

The presence and release of alpha 2-antiplasmin from human platelets

1981 • 8 citations

Human platelet fibrinogen: purification and hemostatic properties

1985 • 7 citations

Fibronectin binding to thrombin-stimulated platelets: evidence for fibrin(ogen) independent and dependent pathways

1985 • 3 citations

Isoelectric characteristics and surface radioiodination of normal and thrombasthenic platelet membrane glycoproteins

1981 • 3 citations