Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle

[56] Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

1991 • 3,691 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member

1992 • 2,719 citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

1996 • 1,045 citations

Origins of Cell Polarity

1996 • 1,024 citations

The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation.

1995 • 896 citations

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

1996 • 872 citations

Genetic control of cell size at cell division in yeast

1975 • 846 citations

Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

1995 • 760 citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

1995 • 711 citations

p160^ROCK, a Rho‐associated coiled‐coil forming protein kinase, works downstream of Rho and induces focal adhesions

1997 • 510 citations

The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

1988 • 493 citations

Growth in cell length in the fission yeast Schizosaccharomyces pombe

1985 • 466 citations

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1993 • 446 citations

tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell

1997 • 354 citations

Cooperative interaction of S. pombe proteins required for mating and morphogenesis

1994 • 303 citations

Emerging from the Pak: the p21-activated protein kinase family

1997 • 285 citations

cot-1, a gene required for hyphal elongation in Neurospora crassa, encodes a protein kinase.

1992 • 235 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe.

1994 • 217 citations

Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.

1995 • 210 citations

Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe.

1995 • 170 citations

Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.

1995 • 158 citations

Drosophila in cancer research: the first fifty tumor suppressor genes

1994 • 109 citations

Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase.

1995 • 79 citations

The highly conserved skb1 gene encodes a protein that interacts with Shk1, a fission yeast Ste20/PAK homolog

1996 • 68 citations

Cdc42p GTPase Is Involved in Controlling Polarized Cell Growth in Schizosaccharomyces pombe

1994 • 67 citations

Phosphorylation Reactions of Recombinant Human Myotonic Dystrophy Protein Kinase and Their Inhibition

1994 • 51 citations

Transposon tools for recombinant DNA manipulation: characterization of transcriptional regulators from yeast, Xenopus, and mouse.

1996 • 50 citations

Myotonic dystrophy, knockouts, warts

1996 • 17 citations