Conversion of the E1A Cys4 zinc finger to a nonfunctional His2,Cys2 zinc finger by a single point mutation.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

X-ray absorption : principles, applications, techniques of EXAFS, SEXAFS, and XANES

1988 • 2,067 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Handbook on Synchrotron Radiation

1987 • 1,263 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

Zinc fingers: Gilt by association

1988 • 799 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

1980 • 772 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Three-Dimensional Solution Structure of a Single Zinc Finger DNA-Binding Domain

1989 • 630 citations

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

1990 • 609 citations

Identification of a cellular transcription factor involved in E1A trans-activation

1986 • 551 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1990 • 391 citations

Xenopus transcription factor A requires zinc for binding to the 5 S RNA gene.

1983 • 356 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Zinc-Dependent Structure of a Single-Finger Domain of Yeast ADR1

1988 • 314 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

EXAFS study of the zinc-binding sites in the protein transcription factor IIIA

1986 • 247 citations

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

1981 • 237 citations

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1987 • 227 citations

DNA binding specificity of steroid receptors

1989 • 212 citations

HeLa Cell β-Tubulin Gene Transcription Is Stimulated by Adenovirus 5 in Parallel with Viral Early Genes by an E1a-Dependent Mechanism

1984 • 187 citations

Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein

1987 • 169 citations

E1A Control of Gene Expression Is Mediated by Sequences 5′ to the Transcriptional Starts of the Early Viral Genes

1983 • 169 citations

Transcriptional Activation and Subsequent Control of the Human Heat Shock Gene During Adenovirus Infection

1983 • 131 citations

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.

1988 • 119 citations

Solution structure of a zinc finger domain of yeast ADR1

1990 • 115 citations

Adenovirus E1a Gene Product Expressed at High Levels in Escherichia coli Is Functional

1984 • 111 citations

Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA

1988 • 102 citations

Disruption of a putative Cys–zinc interaction eliminates the biological activity of the Krüppel finger protein

1988 • 84 citations

The yeast regulatory protein ADR1 binds in a zinc-dependent manner to the upstream activating sequence of ADH2.

1988 • 81 citations

DNA-binding properties of an adenovirus 289R E1A protein.

1988 • 77 citations

Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions

1985 • 69 citations

An x-ray absorption study of the iron site in bacterial photosynthetic reaction centers

1982 • 62 citations

Regulation of adenovirus transcription by an E1a gene in microinjected Xenopus laevis oocytes.

1983 • 52 citations

The active site of hemerythrin as determined by x-ray absorption fine structure

1988 • 52 citations

Multiple transcription factor binding sites mediate adenovirus E1A transactivation

1989 • 37 citations

Cysteine residues in the zinc finger and amino acids adjacent to the finger are necessary for DNA binding by the LAC9 regulatory protein of Kluyveromyces lactis.

1988 • 37 citations

An adenovirus type 5 E1A protein with a single amino acid substitution blocks wild-type E1A transactivation.

1987 • 34 citations

The Yeast Regulatory Protein ADR1 Binds in a Zinc-Dependent Manner to the Upstream Activating Sequence of ADH2

1988 • 27 citations

Regulation of Adenovirus Transcription by an E1a Gene in MicroinjectedXenopus laevisOocytes

1983 • 23 citations

An Adenovirus Type 5 ElA Protein with a Single Amino Acid Substitution Blocks Wild-Type ElA Transactivation

1987 • 15 citations

Cysteine Residues in the Zinc Finger and Amino Acids Adjacent to the Finger Are Necessary for DNA Binding by the LAC9 Regulatory Protein of Kluyveromyces lactis

1988 • 12 citations