Dopamine D1 antagonist SCH23390 attenuates self-administration of both cocaine and fentanyl in rats

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Brain Dopamine and Reward

1989 • 1,899 citations

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

1988 • 913 citations

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

1984 • 644 citations

Neurobiology of opiate abuse

1992 • 546 citations

Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats

1982 • 451 citations

Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neuroleptics

1984 • 373 citations

Heroin reward is dependent on a dopaminergic substrate

1981 • 333 citations

Attenuation of heroin reward in rats by disruption of the mesolimbic dopamine system

1983 • 309 citations

The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat

1987 • 281 citations

Self-administration of methionine enkephalin into the nucleus accumbens

1984 • 238 citations

Parameters of self-administration of cocaine in rats under a progressive-ratio schedule

1993 • 217 citations

Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat

1991 • 172 citations

Blockade of D-1 receptors by SCH 23390 antagonizes morphine- and amphetamine-induced place preference conditioning

1987 • 169 citations

Catalepsy induced by SCH 23390 in rats

1985 • 148 citations

Cocaine self-administration is increased by both D1 and D2 dopamine antagonists

1991 • 138 citations

Heroin self-administration in rats under a progressive ratio schedule of reinforcement

1993 • 122 citations

Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration

1991 • 97 citations

Effects of 6-OHDA lesions of the central medial nucleus accumbens on rat intravenous morphine self-administration

1985 • 86 citations

The dopamine hypothesis of opiate reward challenged

1987 • 77 citations

Progressive-ratio performance in the rhesus monkey maintained by opiate infusions

1979 • 76 citations

Cocaine reinforced progressive ratio performance in the rhesus monkey

1978 • 63 citations

Differences in the cataleptogenic actions of SCH23390 and selected classical neuroleptics

1988 • 49 citations

Quantification of SCH 39166, a novel selective D1 dopamine receptor antagonist, in rat brain and blood

1992 • 32 citations

Quantification of R-(+)-7-chloro-8-hydroxyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-methyl-3-benzazepine in brain and blood by use of reversed-phase high-performance liquid chromatography with electrochemical detection

1985 • 30 citations

Dopamine D1 antagonists potentiate the durations of bar and cling catalepsy and the dorsal immobility response in rats

1992 • 24 citations

The Role of Dopamine in Cocaine Use and Abuse

1988 • 22 citations

Self-administration studies on psychological dependence

1979 • 15 citations