Bovine Lactoferrin Can Be Taken Up by the Human Intestinal Lactoferrin Receptor and Exert Bioactivities

Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus

2003 • 5,611 citations

Lactoferrin: Molecular Structure and Biological Function

1995 • 734 citations

Characterization of the Human Upper Gastrointestinal Contents Under Conditions Simulating Bioavailability/Bioequivalence Studies

2005 • 618 citations

Damage of the outer membrane of enteric gram-negative bacteria by lactoferrin and transferrin

1988 • 526 citations

Lactoferrin

2005 • 425 citations

The physiology of lactoferrin

2002 • 402 citations

Three-dimensional structure of diferric bovine lactoferrin at 2.8 Å resolution

1997 • 392 citations

Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA

1995 • 349 citations

Human Intelectin Is a Novel Soluble Lectin That Recognizes Galactofuranose in Carbohydrate Chains of Bacterial Cell Wall

2001 • 339 citations

Molecular Cloning and Functional Expression of a Human Intestinal Lactoferrin Receptor

2001 • 327 citations

Correlative study of hydrochloric acid, pepsin, and intrinsic factor secretion in newborns and infants

1969 • 281 citations

Lactoferrin-lipopolysaccharide interaction: involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharide

1995 • 242 citations

Persistence of Human Milk Proteins in the Breast‐Fed Infant

1987 • 235 citations

Lactoferrin and Iron: structural and dynamic aspects of binding and release

2004 • 227 citations

Isolation and function of a receptor for human lactoferrin in human fetal intestinal brush-border membranes

1991 • 180 citations

Lactoferrin Induces Concentration-Dependent Functional Modulation of Intestinal Proliferation and Differentiation

2007 • 178 citations

The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrumUnusual resistance of human apolactoferrin to proteolytic digestion

1983 • 153 citations

Apo‐ and holo‐lactoferrin are both internalized by lactoferrin receptor via clathrin‐mediated endocytosis but differentially affect ERK‐signaling and cell proliferation in caco‐2 cells

2011 • 148 citations

Glycosylated and unglycosylated human lactoferrins both bind iron and show identical affinities towards human lysozyme and bacterial lipopolysaccharide, but differ in their susceptibilities towards tryptic proteolysis

1995 • 141 citations

X-ray solution scattering reveals conformational changes upon iron uptake in lactoferrin, serum and ovo-transferrins

1992 • 135 citations

Regional Postprandial Differences in pH Within the Stomach and Gastroesophageal Junction

2005 • 133 citations

CHARACTERIZATION AND PROPERTIES OF THE HUMAN AND BOVINE LACTOTRANSFERRINS EXTRACTED FROM THE FAECES OF NEWBORN INFANTS

1982 • 119 citations

Cellular internalization of lactoferrin in intestinal epithelial cells

2004 • 117 citations

Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology

2010 • 113 citations

Oral Administration of Lactoferrin Increases NK Cell Activity in Mice via Increased Production of IL-18 and Type I IFN in the Small Intestine

2006 • 110 citations

Expression, Characterization, and Biologic Activity of Recombinant Human Lactoferrin in Rice

2003 • 105 citations

Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology.

2010 • 100 citations

Concentrations of lactoferrin and iron in human milk at different stages of lactation.

1990 • 98 citations

Receptor-modulated iron release from transferrin: differential effects on N- and C-terminal sites

1991 • 88 citations

α1-Antitrypsin and antichymotrypsin in human milk: origin, concentrations, and stability

2002 • 76 citations

Identification of an import signal for, and the nuclear localization of, human lactoferrin

2001 • 75 citations

Characterization of Recombinant Human Lactoferrin Secreted in Milk of Transgenic Mice

1997 • 68 citations

Orally administered bovine lactoferrin induces caspase-1 and interleukin-18 in the mouse intestinal mucosa: a possible explanation for inhibition of carcinogenesis and metastasis

2003 • 66 citations

Recombinant Human Intelectin Binds Bovine Lactoferrin and Its Peptides

2008 • 58 citations

Iron Saturation Alters the Effect of Lactoferrin on the Proliferation and Differentiation of Human Enterocytes (Caco-2 Cells)

1995 • 53 citations

Human Apo-Lactoferrin Enhances Angiogenesis Mediated by Vascular Endothelial Growth Factor A in vivo

2004 • 50 citations

Potential host-defense role of a human milk vitamin B-12–binding protein, haptocorrin, in the gastrointestinal tract of breastfed infants, as assessed with porcine haptocorrin in vitro

2003 • 50 citations

Lactoferrin‐mediated transfer of iron to intracellular ferritin in human monocytes

1988 • 47 citations

Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early lifeThis paper is one of a selection of papers published in this Special Issue, entitled 7th International Conference on Lactoferrin: Structure, Function, and Applications, and has undergone the Journal's usual peer review process.

2006 • 45 citations

Lactoferrin Down-modulates the Activity of the Granulocyte Macrophage Colony-stimulating Factor Promoter in Interleukin-1β-stimulated Cells

1995 • 44 citations

Fecal Alpha₁‐Antitrypsin in Breast‐Fed Infants Is Derived from Human Milk and Is not Indicative of Enteric Protein Loss

1990 • 34 citations

Self-radioiodination of iodogen

2001 • 33 citations

The secretion of intestinal alkaline phosphatase (IAP) from the enterocyte.

1994 • 25 citations

Expression, Characterization, and Biologic Activity of Recombinant Human Lactoferrin in Rice

2003 • 10 citations