Regulation of Potassium Channels by Nonsedating Antihistamines

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Terfenadine-Ketoconazole Interaction

1993 • 654 citations

Mechanism of the Cardiotoxic Actions of Terfenadine

1993 • 627 citations

Torsades de pointes occurring in association with terfenadine use

1990 • 550 citations

Comparison of potassium currents in rabbit atrial and ventricular cells.

1988 • 382 citations

Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin

1992 • 373 citations

Early outward current in rat single ventricular cells.

1984 • 332 citations

The Pharmacology and Use of H₁-Receptor-Antagonist Drugs

1994 • 326 citations

Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide.

1992 • 316 citations

Two types of transient outward currents in adult human atrial cells

1987 • 231 citations

Ionic basis of the different action potential configurations of single guinea‐pig atrial and ventricular myocytes.

1985 • 223 citations

Cesium chloride-induced long QT syndrome: demonstration of afterdepolarizations and triggered activity in vivo.

1985 • 206 citations

Histamine and cardiac arrhythmias.

1986 • 187 citations

Block of delayed rectifier potassium current, IK, by flecainide and E-4031 in cat ventricular myocytes.

1990 • 176 citations

Cardiotoxic effect with convulsions in terfenadine overdose.

1989 • 168 citations

Mechanism of receptor‐mediated modulation of the delayed outward potassium current in guinea‐pig ventricular myocytes.

1990 • 167 citations

Torsade de pointes after astemizole overdose.

1986 • 157 citations

Tedisamil blocks the transient and delayed rectifier K+ currents in mammalian cardiac and glial cells.

1990 • 155 citations

Effects of terfenadine and its metabolites on a delayed rectifier K+ channel cloned from human heart.

1993 • 136 citations

Beta-adrenergic modulation of cardiac ion channels. Differential temperature sensitivity of potassium and calcium currents.

1989 • 114 citations

Potassium rectifier currents differ in myocytes of endocardial and epicardial origin.

1992 • 110 citations

Erythromycin-induced long QT syndrome: Concordance with quinidine and underlying cellular electrophysiologic mechanism

1990 • 106 citations

Cardiac histamine receptors: differences between left and right atria and right ventricle.

1977 • 102 citations

Distinct voltage-dependent regulation of a heart-delayed IK by protein kinases A and C

1991 • 97 citations

Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp

1990 • 93 citations

The transient K+ current in rat ventricular myocytes: evaluation of its Ca2+ and Na+ dependence.

1991 • 86 citations

Characterization of the inward-rectifying potassium current in cat ventricular myocytes.

1988 • 80 citations

Accidental astemizole overdose in young children

1991 • 78 citations

Cardiotoxic effects of astemizole overdose in children

1992 • 77 citations

Torsade de pointes ventricular tachycardia associated with astemizole overdose

1988 • 66 citations

Dynamics of the inward rectifier K+ current during the action potential of guinea pig ventricular myocytes

1991 • 64 citations

Astemizole-Induced Cardiac Conduction Disturbances in a Child

1991 • 36 citations

Prolonged Q-T interval following astemizole overdose.

1989 • 35 citations

Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes

1990 • 32 citations

Nonsedating histamine H1-receptor antagonists.

1989 • 26 citations

Contribution of Delayed Rectifier and Inward Rectifier to Repolarization of the Action Potential: Pharmacologic Separation

1992 • 22 citations

The New H 1 Antihistamines

1993 • 19 citations

Potassium Channels and the Repolarization of Cardiac Cells

1990 • 8 citations