Diaspirin Cross-linked Hemoglobin Effectively Restores Pancreatic Microcirculatory Failure in Hemorrhagic Shock

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

Lipid peroxidation and antioxidants as biomarkers of tissue damage

1995 • 1,845 citations

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.

1994 • 1,631 citations

Hemoglobin. A biologic fenton reagent.

1984 • 582 citations

Susceptibility of the Pancreas to Ischemic Injury in Shock

1978 • 308 citations

Pancreatic ischaemia in experimental acute pancreatitis: Mechanism, significance and therapy

1990 • 276 citations

Specificity of the thiobarbituric acid reaction: its use in studies of lipid peroxidation.

1988 • 240 citations

Controlled Safety Study of a Hemoglobin-Based Oxygen Carrier, DCLHb, in Acute Ischemic Stroke

1999 • 226 citations

Granulocytes and no-reflow phenomenon in irreversible hemorrhagic shock.

1988 • 177 citations

Inhibition of CD18-dependent neutrophil adherence reduces organ injury after hemorrhagic shock in primates.

1990 • 158 citations

Systemic and subcutaneous microvascular Po2 dissociation during 4-h hemorrhagic shock in conscious hamsters

1996 • 146 citations

Phase I study of the safety and pharmacologic effects of diaspirin cross-linked hemoglobin solution

1996 • 139 citations

The application of stereological principles to morphometry of the microcirculation in different tissues

1977 • 130 citations

Functional Capillary Density: An Indicator of Tissue Perfusion?

1995 • 125 citations

Initial evaluation of diaspirin cross-linked hemoglobin (DCLHb[trademark symbol]) as a vasopressor in critically ill patients

1997 • 119 citations

Role of endothelin in the cardiovascular effects of diaspirin crosslinked and stroma reduced hemoglobin

1996 • 114 citations

Ischemia reperfusion of the pancreas: A new in vivo model for acute pancreatitis in rats

1995 • 95 citations

USE OF BASE DEFICIT TO COMPARE RESUSCITATION WITH LACTATED RINGERʼS SOLUTION, HAEMACCEL, WHOLE BLOOD, AND DIASPIRIN CROSS-LINKED HEMOGLOBIN FOLLOWING HEMORRHAGE IN RATS

1993 • 91 citations

Role of NO mechanism in cardiovascular effects of diaspirin cross-linked hemoglobin in anesthetized rats

1995 • 79 citations

Regional blood flow alterations after bovine fumaryl beta beta-crosslinked hemoglobin transfusion and nitric oxide synthase inhibition

1996 • 79 citations

Diaspirin Crosslinked Hemoglobin Improves Systemic Oxygen Uptake in Oxygen Supply–dependent Septic Rats

1997 • 74 citations

Focal Cerebral Ischemia in Rats

1993 • 63 citations

Use of antioxidant therapy in shock and trauma.

1991 • 61 citations

Effect of diaspirin cross-linked hemoglobin on endothelin-1 and blood pressure in acute ischemic stroke in man

1998 • 51 citations

Effects of endothelin on microcirculation of the pancreas

1992 • 49 citations

Effects of diaspirin-cross-linked hemoglobin (DCLHbTM) on the microcirculation of striated skin muscle in the hamster: A study on safety and toxicity

1997 • 49 citations

Ischemia and reperfusion in pancreas

1997 • 48 citations

DOSE-DEPENDENT EFFECT OF DIASPIRIN CROSS-LINKED HEMOGLOBIN ON REGIONAL BLOOD CIRCULATION OF SEVERELY HEMORRHAGED RATS

1998 • 46 citations

Validation of Virus Inactivation by Heat Treatment in the Manufacture of Diaspqun Crosslinksd Hemoglobin

1992 • 29 citations

Small-volume resuscitation restores hemorrhage-induced microcirculatory disorders in rat pancreas

1996 • 29 citations

Attenuation of postischemic reperfusion injury in striated skin muscle by diaspirin-cross-linked Hb

1998 • 25 citations

In Vivo Documentation of an Arteriovenous Shunt in Rat Pancreatic Acinar Tissue

1996 • 24 citations

Effects of diaspirin crosslinked haemoglobin during coronary angioplasty in the swine

1994 • 23 citations

Diaspirin crosslinked hemoglobin (DCLHbTM): Absence of increased free radical generation following administration in a rabbit model of renal ischemia and reperfusion

1995 • 22 citations

Reactive oxygen species in the cellular pathophysiology of shock.

1998 • 18 citations

Absence of Immunogenicity of Diaspirin Cross-Linked Hemoglobin in Humans

1998 • 17 citations

Experimental Subarachnoid Hemorrhage in Rats

1997 • 16 citations

Effect of diaspirin cross-linked hemoglobin on normal and postischemic microcirculation of the rat pancreas

1999 • 15 citations

Role of xanthine oxidase and eicosanoids in development of pancreatic ischemia-reperfusion injury

1995 • 14 citations

Vitamin E: Focus on Microcirculation

1998 • 12 citations

Inhaled Nitric Oxide Attenuates Increased Pulmonary Artery Pressure Following Diaspirin Crosslinked Hemoglobin (Dclhb) Administration

1999 • 11 citations