Kinetic Parameters of 5α-Reductase Activity in Stroma and Epithelium of Normal, Hyperplastic, and Carcinomatous Human Prostates*

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Enzyme kinetics; behavior and analysis of rapid equilibrium and steady state enzyme systems

1994 • 3,007 citations

The Conversion of Testosterone to 5α-Androstan-17β-ol-3-one by Rat Prostate in Vivo and in Vitro

1968 • 1,023 citations

Dihydrotestosterone in prostatic hypertrophy

1970 • 409 citations

COMPARATIVE ASPECTS OF DEVELOPMENT AND STRUCTURE IN THE PROSTATE.

1963 • 261 citations

The prostate gland : morphology and pathobiology

1988 • 246 citations

The accessory reproductive glands of mammals

1961 • 219 citations

Tissue content of dihydrotestosterone in human prostatic hyperplasis is not supranormal.

1983 • 177 citations

Stroma of human benign prostatic hyperplasia: preferential tissue for androgen metabolism and oestrogen binding

1981 • 141 citations

COMPARISON OF ANDROGEN METABOLITES IN BENIGN PROSTATIC HYPERTROPHY (BPH) AND NORMAL PROSTATE

1976 • 138 citations

ANDROGEN LEVELS IN THE PLASMA AND PROSTATIC TISSUES OF PATIENTS WITH BENIGN HYPERTROPHY AND CARCINOMA OF THE PROSTATE

1976 • 118 citations

BIOCHEMICAL INVESTIGATIONS OF SEPARATED EPITHELIUM AND STROMA FROM BENIGN HYPERPLASTIC PROSTATIC TISSUE

1977 • 117 citations

Changes in Dihydrotestosterone Metabolism Associated with the Development of Canine Benign Prostatic Hyperplasia*

1981 • 102 citations

Inhibition of 5 alpha-reductase, receptor binding, and nuclear uptake of androgens in the prostate by a 4-methyl-4-aza-steroid.

1981 • 101 citations

Changes in the Metabolism of Dihydrotestosterone in the Hyperplastic Human Prostate*

1983 • 96 citations

Androgens and estrogens: their interaction with stroma and epithelium of human benign prostatic hyperplasia and normal prostate.

1983 • 94 citations

Effects and Metabolism of Hormones in Normal and Neoplastic Prostate Tissue

1969 • 82 citations

INCREASED RATIO OF 5α-REDUCTASE: 3α(β)-HYDROXYSTEROID DEHYDROGENASE ACTIVITIES IN THE HYPERPLASTIC HUMAN PROSTATE

1979 • 78 citations

Intratissular androgens in benign prostatic hyperplasia and prostatic cancer

1986 • 73 citations

QUANTIFICATION OF ANDROGEN BINDING, ANDROGEN TISSUE LEVELS, AND SEX HORMONE-BINDING GLOBULIN IN PROSTATE, MUSCLE AND PLASMA OF PATIENTS WITH BENIGN PROSTATIC HYPERTROPHY

1977 • 56 citations

Kinetic analysis of 5α-reductase isoenzymes in benign prostatic hyperplasia (BPH)

1983 • 43 citations

Androgen of the Human Prostate

1976 • 38 citations

Prostatic tissue distribution of 17β-hydroxy-5α-androstan-3-one and of androgen receptors in benign hyperplasia

1980 • 38 citations

Changes in dihydrotestosterone metabolism and the development of benign prostatic hyperplasia in the aging beagle

1983 • 36 citations

Endogenous androgen levels in epithelium and stroma of human benign prostatic hyperplasia and normal prostate

1982 • 36 citations

Studies of the nuclear 5α-reductase of human hyperplastic prostatic tissue

1981 • 35 citations

Discrimination between Normal, Hyperplastic and Malignant Human Prostatic Tissues by Enzymatic Profiles

1985 • 35 citations

Comparison of nuclear 5α-reductase activities in the stromal and epithelial fractions of human prostatic tissue

1987 • 34 citations

Prostatic cancer. I. 6-Methylene-4-pregnen-3-ones as irreversible inhibitors of rat prostatic Δ4-3 ketosteroid 5α-reductase

1981 • 33 citations

Correlation of Biochemical (Receptors, Endogenous Tissue Hormones) and Quantitative Morphologic (Stereologic) Findings in Normal and hyperplastic Human Prostates

1987 • 31 citations

Testosterone Metabolism of Fibroblasts Grown From Prostatic Carcinoma, Benign Prostatic Hyperplasia and Skin Fibroblasts

1982 • 24 citations

5α-androstane-3β,17β-diol hydroxylating enzymes in stroma and epithelium of human benign prostatic hyperplasia (BPH)

1987 • 22 citations

5α-Androstane-3β, 17β-diol and 5α-androstane-3β,7α, 17β-triol in the human hyperplastic prostate

1980 • 20 citations

Concentrations of androgens in human benign prostatic hypertrophic tissues incubated for up to three days

1986 • 16 citations

5α-Reductase activity in stroma and epithelium of rat prostate and epididymis. A contribution to elucidation of the mechanism for development of hyperplastic growth of prostatic tissue

1983 • 15 citations

Correlated Biochemical and Stereological Studies on Testosterone Metabolism in the Stromal and Epithelial Compartment of Human Benign Prostatic Hyperplasia

1985 • 10 citations

Metabolism of steroids in the prostate

1983 • 4 citations

Hormonal environment of the normal prostate

1983 • 2 citations

Heterogeneity of repartition of 5αreductase activity in a same prostate affects low affinity rather than high affinity systems

1987 • 1 citations