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Metabolism of steroids in the prostate

Data up to Jan 2025

Published1983
Citations4
References116

Total Citations Per Year

Abstract

References (116)

The Conversion of Testosterone to 5α-Androstan-17β-ol-3-one by Rat Prostate in Vivo and in Vitro

1968 • 1,023 citations

Selective Retention of Dihydrotestosterone by Prostatic Nuclei

1968 • 532 citations

The Intranuclear Binding of Testosterone and 5α-Androstan-17β-ol-3-one by Rat Prostate

1968 • 401 citations

Comparison of spontaneous and experimentally induced canine prostatic hyperplasia.

1979 • 280 citations

A Comparative Study of the Conversion of Testosterone to 17β-Hydroxy-5α-androstan-3-one (Dihydrotestosterone) by Prostate and Epididymis

1969 • 258 citations

The Intranuclear Metabolism of Testosterone in the Accessory Organs of Reproduction

1970 • 249 citations

Metabolism of Testosterone and Action of Metabolites on Prostate Glands grown in Organ Culture

1968 • 233 citations

STEROIDS OF ADRENAL ORIGIN METABOLIZED BY HUMAN PROSTATIC TISSUE BOTH IN VIVO AND IN VITRO

1974 • 192 citations

Normal and abnormal growth of the prostate

1975 • 189 citations

Dihydrotestosterone Formation in Fetal Tissues of the Rabbit and Rat

1971 • 175 citations

Partial Characterization of the Nuclear Reduced Nicotinamide Adenine Dinucleotide Phosphate: Δ4-3-Ketosteroid 5α-Oxidoreductase of Rat Prostate

1971 • 169 citations

Comparison of the Metabolites Formed in Rat Prostate Following thein VivoAdministration of Seven Natural Androgens*

1971 • 154 citations

Hormone metabolism and action: Testosterone and metabolites in prostate organ culture

1971 • 139 citations

COMPARISON OF ANDROGEN METABOLITES IN BENIGN PROSTATIC HYPERTROPHY (BPH) AND NORMAL PROSTATE

1976 • 138 citations

Androgens: Biochemistry, Physiology, and Clinical Significance

1956 • 131 citations

ANDROGEN LEVELS IN THE PLASMA AND PROSTATIC TISSUES OF PATIENTS WITH BENIGN HYPERTROPHY AND CARCINOMA OF THE PROSTATE

1976 • 118 citations

BIOCHEMICAL INVESTIGATIONS OF SEPARATED EPITHELIUM AND STROMA FROM BENIGN HYPERPLASTIC PROSTATIC TISSUE

1977 • 117 citations

A comparative study of binding, metabolism and endogenous levels of androgens in normal, hyperplastic and carcinomatous human prostate

1979 • 117 citations

THE PHYSIOLOGY OF THE PROSTATE GLAND

1945 • 114 citations

Biology of the prostate and related tissues

1963 • 105 citations

CHARACTERIZATION OF THE SPECIFIC ANDROGEN RECEPTORS IN THE HUMAN PROSTATE GLAND

1973 • 94 citations

The Metabolism of Pyrene

1957 • 94 citations

Catabolism of [4-14C]testosterone by subcellular fractions of human prostate

1966 • 88 citations

Studies on the Mechanism of 3α-Androstanediol-Induced Growth of the Dog Prostate*

1978 • 78 citations

INCREASED RATIO OF 5α-REDUCTASE: 3α(β)-HYDROXYSTEROID DEHYDROGENASE ACTIVITIES IN THE HYPERPLASTIC HUMAN PROSTATE

1979 • 78 citations

The Effect of Androgenic Hormones on the Reduced Nicotinamide Adenine Dinucleotide Phosphate: Δ4-3-Ketosteroid 5α-Oxidoreductase of Rat Ventral Prostate*

1973 • 70 citations

The Metabolism in Vivo of Δ4-Androstene-3,17-dione-7-H3; Its Localization in the Ventral Prostate and Other Tissues of the Rat

1961 • 69 citations

Uptake and Metabolismin Vivoof Testosterone-1,2-3H by Accessory Sex Organs of Male Rats; Influence of Some Hormonal Compounds

1969 • 63 citations

Androgen dynamics in vitro in the normal and hyperplastic human prostate gland

1971 • 61 citations

THE INFLUENCE OF SERUM ON UPTAKE, CONVERSION AND ACTION OF TESTOSTERONE IN RAT PROSTATE GLANDS IN ORGAN CULTURE

1972 • 61 citations

THE FATE OF C14-TESTOSTERONE AND C14-PROGESTERONE IN MICE AND RATS1,2,3

1952 • 60 citations

Conversion of Androstenedione to Estrone in Human Fibroblasts Cultured from Prostate, Genital and Nongenital Skin

1979 • 59 citations

EFFECT OF OESTRADIOL-17β AND PROGESTERONE ON THE METABOLISM OF TESTOSTERONE BY HUMAN PROSTATIC TISSUE

1974 • 57 citations

BINDING AND METABOLISM OF 5α-ANDROSTANE-3α,17β-DIOL AND OF 5α-ANDROSTANE-3β,17β-DIOL IN THE PROSTATE, SEMINAL VESICLES AND PLASMA OF MALE RATS: STUDIES IN VIVO AND IN VITRO

1975 • 54 citations

Studies on the Relationship between Androgen Receptors and the Transport of Androgens in Rat Prostate

1973 • 52 citations

The Androgens of the testis

1970 • 48 citations

A direct effect of estrogens on prostatic metabolism of testosterone.

1969 • 47 citations

RELATIONSHIPS BETWEEN OESTRADIOL-17β, TESTOSTERONE, DIHYDROTESTOSTERONE AND 5α-ANDROSTANE-3α,17β-DIOL IN HUMAN BENIGN HYPERTROPHY AND CARCINOMA OF THE PROSTATE

1981 • 45 citations

The zonal anatomy of the prostate in man and in the Rhesus monkey (Macaca Mulatta)

1977 • 45 citations

STUDIES IN STEROID METABOLISM

1954 • 43 citations

Reduction of 5α-Position of Testosterone in the Rat Ventral Prostate

1969 • 42 citations

The identification and characterization of a new c1903 steroid metabolite in the eat ventral prostate: 5α-androstane-3β, 6α, 17β-triol

1979 • 41 citations

Comparison of testosterone, 5α-dihydrotestosterone and 5α-androstane-3β,17β-diol metabolisms in human normal and hyperplastic prostates

1978 • 40 citations

Metabolism of Testosterone in the Human Prostate and Seminal Vesicles

1977 • 39 citations

Metabolism of C19-radiosteroids by explants of canine prostate and epididymis with disposition as hydroxylated products: A possible mechanism for androgen inactivation

1979 • 39 citations

Androgen of the Human Prostate

1976 • 38 citations

Dihydrotestosterone concentration in prostate cancer tissue as a predictor of tumor differentiation and hormonal dependency.

1978 • 38 citations

METABOLISM AND MODE OF ACTION OF ANDROGENS IN TARGET TISSUES OF MALE RATS

1972 • 38 citations

ANDROGENIC RECEPTORS IN HUMAN BENIGN NODULAR PROSTATIC HYPERPLASIA

1971 • 37 citations

DEMONSTRATION OF A SPECIFIC CYTOSOL RECEPTOR IN THE NORMAL AND HYPERPLASTIC CANINE PROSTATE FOR 5α-ANDROSTANE-3α, 17α-DIOL

1975 • 37 citations

HUMAN PROSTATIC CARCINOMA: SIGNIFICANT DIFFERENCES IN ITS ANDROGEN BINDING AND METABOLISM COMPARED TO THE HUMAN BENIGN PROSTATIC HYPERTROPHY

1978 • 36 citations

Demonstration of a specific cytosol receptor in the normal and hyperplastic canine prostate for 5alpha-androstane-3alpha, 17alpha-diol.

1975 • 36 citations

3α-Reduction of 5α-Dihydrotestosterone by Rat Ventral Prostate

1972 • 36 citations

Formation of 5α-Androstane-3α,17β-diol by Normal and Hypertrophic Human Prostate

1977 • 35 citations

Proceedings: Effects of housing density and androgen administration on inter-male fighting behaviour in castrated mice.

1975 • 35 citations

Testosterone action in the rat ventral prostate. The effects of diethylstilboestrol and cyproterone acetate on the metabolism of [3H]testosterone and the retention of labelled metabolites by rat ventral prostate in vivo and in vitro

1971 • 35 citations

THE INFLUENCE OF OESTRADIOL ON THE METABOLISM OF ANDROGENS BY HUMAN PROSTATIC TISSUE

1977 • 33 citations

EFFECTS OF PROLACTIN AND/OR TESTOSTERONE ON NUCLEIC ACID LEVELS IN PROSTATE GLANDS OF NORMAL AND CASTRATED RATS

1975 • 32 citations

Macromolecular binding and metabolism of progesterone in the decidual and pseudopregnant rat and rabbit uterus☆

1971 • 31 citations

TESTOSTERONE METABOLISM IN THE PROSTATE.

1963 • 31 citations

3-O-methyl-<scp>d</scp>-mannose from Streptomyces griseus

1966 • 31 citations

Metabolism of Testosterone-4-14C by the Canine Prostate and Urinary Bladderin Vivo

1970 • 29 citations

CHARACTERISTICS OF THE NUCLEAR AND MICROSOMAL STEROID Δ4-5α-HYDROGENASE OF THE RAT PROSTATE

1974 • 28 citations

Metabolism of 19-nortestosterone by human prostate

1966 • 28 citations

THE EFFECT OF TESTOSTERONE AND TESTOSTERONE METABOLITES ON THE FINE STRUCTURE OF THE RAT PROSTATE GLAND IN ORGAN CULTURE

1972 • 28 citations

Intranuclear Metabolism of Progesterone-1,2-3H in the Hen Oviduct

1970 • 28 citations

The metabolism of [4-14C]progesterone by hypertrophic and carcinomatous human prostate tissue

1965 • 28 citations

The effect of oestrogen on the prostatic metabolism of testosterone in tissue culture

1971 • 27 citations

Metabolism of 5α-dihydrotestosterone in human benign hyperplastic prostate

1977 • 25 citations

In vitro studies of the regulation of androgen-tissue relationship in normal canine and hyperplastic human prostate

1974 • 24 citations

THE METABOLISM OF STEROIDS IN THE CANINE PROSTATE AND TESTIS

1971 • 23 citations

ANDROGEN DYNAMICS IN VITRO IN THE CANINE PROSTATE GLAND

1972 • 22 citations

EFFECTS OF TAMOXIFEN ON THE BINDING AND METABOLISM OF TESTOSTERONE BY HUMAN PROSTATIC TISSUE AND PLASMA IN VITRO

1979 • 21 citations

5α-Androstane-3β, 17β-diol and 5α-androstane-3β,7α, 17β-triol in the human hyperplastic prostate

1980 • 20 citations

Metabolism and action of steroid hormones on human benign prostatic hyperplasia and prostatic carcinoma grown in organ culture

1979 • 19 citations

In vivo metabolism of 3H-testosterone in adult male rats: Effects of estrogen administration

1975 • 19 citations

METABOLISM OF TESTOSTERONE BY NEOPLASTIC HUMAN PROSTATE*

1953 • 19 citations

METABOLISM AND MODE OF ACTION OF ANDROGENS IN TARGET TISSUES OF MALE RATS

1972 • 19 citations

The metabolism of [14C]estrone by hypertrophic and carcinomatous human prostate tissue

1965 • 19 citations

Correlative study of the morphology and C19‐steroid metabolism of benign and cancerous human prostatic tissue

1977 • 18 citations

Altered Androgen Metabolism in Metastatic Prostate Cancer

1978 • 17 citations

Androgens: biochemistry, physiology, and clinical significance

1956 • 17 citations

PRODUCTION AND SECRETION OF 5α-DIHYDROTESTOSTERONE BY THE CANINE PROSTATE

1972 • 17 citations

Androgen Binding and Metabolism in the Human Prostate

1976 • 16 citations

TESTOSTERONE METABOLISM IN SUBCELLULAR FRACTIONS OF RAT PROSTATE

1973 • 16 citations

Effect of estradiol on the metabolism of testosterone by rat prostate

1973 • 16 citations

The metabolism of [4-14C]4-androstene-3,17-dione by normal human prostatic tissue

1964 • 16 citations

Uptake, metabolism and binding of various androgens in human prostatic tissue: In vivo and in vitro studies

1975 • 15 citations

Studies on steroid metabolism in human prostatic tissue

1970 • 14 citations

STUDIES ON THE UPTAKE AND BINDING OF 5α-ANDROSTANE-3α,17α-DIOL BY CANINE PROSTATIC NUCLEI

1976 • 14 citations

Hormone Metabolism and Action: III. Metabolism of 3α–Hydroxy and 3β–Hydroxy C19–Steroids in Prostate Organ Culture

1972 • 13 citations

Testosterene and perogsterone metabolism and their interaction in the human hyperplastic prostate

1975 • 13 citations

The Effect of Antiandrogens and Stilboestrol on the Cytosol Receptor in Rat Prostate

1977 • 11 citations

Identification of a Prostate in Female Praomys (Mastomys) Natalensis using 3H steroids

1975 • 10 citations

Identification of an androgen receptor in the cytosol of the female Mastomys prostate

1977 • 10 citations

THE DISTRIBUTION OF C14 IN MICE AFTER A SUBCUTANEOUS INJECTION OF TESTOSTERONE-4-C14

1956 • 10 citations

3alpha-Reduction of dihydrotestosterone in human normal and hypertrophic prostatic tissues.

1975 • 10 citations

DPN- AND TPN-17β-HYDROXY-C19-STEROID DEHYDROGENASES; INTRACELLULAR LOCALIZATION IN DOG PROSTATE

1968 • 9 citations

Uptake and distribution of 3H testosterone in tissues of male Praomys (Mastomys) Natalensis

1976 • 8 citations

Inhibition of the nuclear dihydrotestosterone receptor complex from rat ventral prostate by antiandrogens and stilboestrol

1978 • 8 citations

Altered Androgen Metabolism in Carcinoma of the Prostate

1981 • 8 citations

METABOLISM OF TESTOSTERONE AND 5α-REDUCED ANDROGENS BY THE RABBIT PROSTATE AND EPIDIDYMIS: STUDIES IN VITRO AND IN VIVO

1979 • 7 citations

Receptor protein for dihydrotestosterone in nuclei of the female prostate of Praomys (Mastomys) natalensis.

1978 • 7 citations

PARTIAL SEPARATION OF A 3α-KETOSTEROID OXIDOREDUCTASE AND AN ANDROGEN BINDING SUBSTANCE PRESENT IN RAT VENTRAL PROSTATE CYTOPLASM

1970 • 7 citations

A soluble androgen receptor in the cytoplasm of the male mastomys prostate

1978 • 6 citations

Androgen Metabolism within the Lobes of Rhesus Monkey Prostate

1981 • 6 citations

Metabolism in vitro of 3H-testosterone in testis, epididymis & sex accessories of the rhesus monkey Macaca mulatta: effects of cyproterone acetate on androgen metabolism.

1977 • 5 citations

Androgen metabolism by human prostatic tumours in organ culture

1983 • 4 citations

Nuclear androgen receptors in the prostate of male Praomys (Mastomys) Natalensis

1979 • 4 citations

Metabolism of testosterone in muscular tissue

1970 • 4 citations

Testosterone metabolism in benign prostatic hypertrophy. Suppression by diethylstilbestrol and gestonorone capronate.

1974 • 4 citations

Androgen Regulation in the Prostate of Rhesus Monkey (Macaca Mulatta)

1981 • 3 citations

Reduction of 5a position of testosterone in the rat ventral prostate

1969 • 2 citations

The interconversion of oestrone and oestradiol by human endometrium and human benign prostatic hyperplasia in organ culture

1970 • 2 citations

Benign Prostatic Hyperplasia

2008 • 2 citations

[Metabolism of testosterone in normal and neoplastic human tissue].

1959 • 1 citations

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