5 Oestrogens and atherosclerotic vascular disease—lipid factors

Beyond Cholesterol

1989 • 6,533 citations

High density lipoprotein as a protective factor against coronary heart disease

1977 • 5,019 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Regression of Coronary Artery Disease as a Result of Intensive Lipid-Lowering Therapy in Men with High Levels of Apolipoprotein B

1990 • 2,192 citations

Postmenopausal Estrogen Therapy and Cardiovascular Disease

1991 • 2,008 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

Beneficial Effects of Combined Colestipol-Niacin Therapy on Coronary Atherosclerosis and Coronary Venous Bypass Grafts

1987 • 1,651 citations

Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidence

1991 • 1,603 citations

Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study.

1987 • 1,379 citations

Estrogen and Coronary Heart Disease in Women

1991 • 1,237 citations

Effects of Postmenopausal Estrogen Replacement on the Concentrations and Metabolism of Plasma Lipoproteins

1991 • 1,158 citations

Menopause and the Risk of Coronary Heart Disease in Women

1987 • 1,137 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Menopause and Risk Factors for Coronary Heart Disease

1989 • 1,036 citations

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.

1990 • 1,020 citations

Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography.

1986 • 933 citations

A Prospective Study of Postmenopausal Estrogen Therapy and Coronary Heart Disease

1985 • 845 citations

Regression of Coronary Atherosclerosis During Treatment of Familial Hypercholesterolemia With Combined Drug Regimens

1990 • 793 citations

Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis

1989 • 696 citations

The triglyceride issue: A view from Framingham

1986 • 675 citations

Plasma high density lipoproteins. Metabolism and relationship to atherogenesis.

1990 • 660 citations

Decreased Mortality in Users of Estrogen Replacement Therapy

1991 • 642 citations

Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins].

1980 • 639 citations

Postmenopausal Estrogen Use, Cigarette Smoking, and Cardiovascular Morbidity in Women over 50

1985 • 613 citations

Estrogen modulates responses of atherosclerotic coronary arteries.

1990 • 605 citations

Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone.

1990 • 603 citations

Lipoproteins and Atherogenesis

1990 • 549 citations

Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis

1987 • 477 citations

Biologic effects of transdermal estradiol

1987 • 467 citations

Pulsatility index in internal carotid artery in relation to transdermal oestradiol and time since menopause

1991 • 394 citations

Postmenopausal Estrogen and Prevention Bias

1991 • 389 citations

Effects of Tamoxifen on Cardiovascular Risk Factors in Postmenopausal Women

1991 • 380 citations

Estrogen Replacement and Coronary Artery Disease

1990 • 379 citations

The Effects of Estrogen Administration on Plasma Lipoprotein Metabolism in Premenopausal Females

1983 • 340 citations

Postmenopausal Estrogen Use and Coronary Atherosclerosis

1988 • 335 citations

Postmenopausal use of estrogen and occlusion of coronary arteries

1988 • 332 citations

Influence of menopause on serum lipids and lipoproteins

1990 • 331 citations

Risk factors for acute myocardial infarction in women: evidence from the Royal College of General Practitioners' oral contraception study.

1989 • 318 citations

Low-density lipoproteins inhibit endothelium-dependent relaxation in rabbit aorta

1987 • 310 citations

Secretion of plasminogen activator inhibitor-1 from cultured human umbilical vein endothelial cells is induced by very low density lipoprotein.

1990 • 300 citations

The Coronary Drug Project

1973 • 298 citations

CLINICAL REVIEW 27 Effects of Hormonal Replacement on Lipids and Lipoproteins in Postmenopausal Women

1991 • 286 citations

Lipoprotein predictors of the severity of coronary artery disease in men and women.

1985 • 279 citations

Differences in Low Density Lipoprotein Subfractions and Apolipoproteins in Premenopausal and Postmenopausal Women*

1988 • 263 citations

Estrogen Use and All-Cause Mortality

1983 • 256 citations

Estrogen and progesterone replacement therapy reduces low density lipoprotein accumulation in the coronary arteries of surgically postmenopausal cynomolgus monkeys.

1991 • 256 citations

Healthy life expectancy: evaluation of global indicator of change in population health.

1991 • 256 citations

On the metabolic function of heparin-releasable liver lipase

1980 • 250 citations

Correlation of Hormones with Lipid and Lipoprotein Levels During Normal Pregnancy and Postpartum*

1987 • 241 citations

Postmenopausal Estrogen Use and Heart Disease Risk Factors in the 1980s

1989 • 233 citations

Lipoprotein (a) : structure, properties and possible involvement in thrombogenesis and atherogenesis

1990 • 230 citations

Cholesterol, lipoproteins, and coronary heart disease in women.

1988 • 228 citations

Menopause: Physiology and Pharmacology

1986 • 214 citations

Effect of estrogen on post-heparin lipolytic activity. Selective decline in hepatic triglyceride lipase.

1977 • 213 citations

Increased mRNA for low density lipoprotein receptor in livers of rabbits treated with 17 alpha-ethinyl estradiol.

1986 • 196 citations

Lipoprotein, apolipoprotein, and lipolytic enzyme changes following estrogen administration in postmenopausal women.

1989 • 187 citations

Estrogens inhibit copper and cell-mediated modification of low density lipoprotein

1991 • 186 citations

The management of persistent menopausal symptoms with oestradiol-testosterone implants: Clinical, lipid and hormonal results

1984 • 185 citations

Effect of combined implants of oestradiol and testosterone on libido in postmenopausal women.

1987 • 177 citations

Effects of high-density lipoprotein on acetylcholine-induced coronary vasoreactivity

1991 • 174 citations

Ovarian hormones and the circulation

1990 • 170 citations

A randomized comparison of nonoral estradiol delivery in postmenopausal women

1988 • 168 citations

ALTERED PLASMA LIPID AND LIPOPROTEIN LEVELS ASSOCIATED WITH ORAL CONTRACEPTIVE AND ŒSTROGEN USE

1979 • 166 citations

Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells.

1983 • 155 citations

Effects of post-menopausal oestrogen-progestogen replacement therapy on serum lipids and lipoproteins: a review

1990 • 147 citations

The Role and Use of Progestogens

1990 • 146 citations

Decrease in Plasma High-Density Lipoprotein Cholesterol Levels at Puberty in Boys With Delayed Adolescence

1987 • 143 citations

Long-term effects of percutaneous estrogens and oral progesterone on serum lipoproteins in postmenopausal women

1987 • 137 citations

Changes in lipoprotein composition during the menstrual cycle

1979 • 135 citations

Risk factors and noncontraceptive estrogen use in women with and without coronary disease

1989 • 134 citations

Biological Effects of Various Doses of Vaginally Administered Conjugated Equine Estrogens in Postmenopausal Women*

1983 • 126 citations

Evaluation of a continuous combined low-dose regimen of estrogen-progestin for treatment of the menopausal patient

1990 • 121 citations

Lipoprotein (a) concentrations in postmenopausal women taking norethisterone.

1991 • 116 citations

Effects of Conjugated Equine Estrogen With and Without Three Different Progestogens on Lipoproteins, High-Density Lipoprotein Subfractions, and Apolipoprotein A-I

1991 • 110 citations

Five years with continuous combined oestrogen/ progestogen therapy. Effects on calcium metabolism, lipoproteins, and bleeding pattern

1990 • 110 citations

Population-based lipoprotein lipid reference values for pregnant women compared to nonpregnant women classified by sex hormone usage

1982 • 105 citations

LIPID METABOLIC STUDIES IN OOPHORECTOMIZED WOMEN. EFFECTS OF THREE DIFFERENT PROGESTOGENS

1979 • 102 citations

L‐norgestrel and progesterone have different influences on plasma lipoproteins

1983 • 95 citations

Presence of multiple subpopulations of lipoproteins of intermediate density in normal subjects.

1986 • 84 citations

Post-menopausal hormone replacement therapy: effects of progestogens on serum lipids and lipoproteins. A review

1986 • 83 citations

A cost‐effectiveness analysis of hormone replacement therapy in the menopause∗

1992 • 83 citations

Effects of estrogen and progesterone on plasma lipoproteins and experimental atherosclerosis in the baboon (Papio sp.).

1991 • 79 citations

Changes in Plasma Lipoprotein and Apolipoprotein Composition in Relation to OralVersusPercutaneous Administration of Estrogen Alone or in Cyclic Association with Utrogestan in Menopausal Women

1991 • 76 citations

Relationship of endogenous sex steroid hormones to lipids and apoproteins in postmenopausal women.

1990 • 76 citations

Cholesterol accumulation in J774 macrophages induced by triglyceride-rich lipoproteins. Comparison of very low density lipoprotein from subjects with type III, IV, and V hyperlipoproteinemias.

1991 • 75 citations

Serum lipids, lipoproteins, and apolipoproteins during postmenopausal estrogen replacement therapy combined with either 19-nortestosterone derivatives or 17-hydroxyprogesterone derivatives

1991 • 73 citations

Massive Hyperlipemia During Estrogen Therapy

1974 • 73 citations

Contraceptive steroids increase hepatic uptake of chylomicron remnants in healthy young women.

1988 • 70 citations

REPRODUCTIVE HISTORY IN WOMEN WITH CORONARY HEART DISEASE: A CASE-CONTROL STUDY

1984 • 69 citations

Controversies concerning the safety of estrogen replacement therapy

1987 • 69 citations

Treatment of Post-Menopausal Hypercholerolaemia with Estradiol

1979 • 69 citations

Synergistic effects of lipid transfers and hepatic lipase in the formation of very small high-density lipoproteins during incubation of human plasma

1990 • 63 citations

Usefulness of the total cholesterol to high-density lipoprotein cholesterol ratio in predicting angiographic coronary artery disease in women

1991 • 62 citations

Oral contraception: past, present, and future perspectives.

1991 • 55 citations

Changes in lipids and lipoproteins with long-term estrogen deficiency and hormone replacement therapy

1991 • 55 citations

Premenopausal determinants of menopausal estrogen use

1991 • 55 citations

Effect of Menstrual Cycle Phase on Plasma Lipids^*

1987 • 53 citations

Subdermal estradiol pellets following hysterectomy and oophorectomy. Effect upon serum estrone, estradiol, luteinizing hormone, follicle-stimulating hormone, corticosteroid binding globulin-binding capacity, testosterone-estradiol binding globulin-binding capacity, lipids, and hot flushes.

1980 • 53 citations

Pregnancy-associated inhibition of coronary artery atherosclerosis in monkeys. Evidence of a relationship with endogenous estrogen.

1987 • 50 citations

Subdermal estradiol pellets following hysterectomy and oophorectomy

1980 • 48 citations

The effects of hormone implants on serum lipoproteins and steroid hormones in bilaterally oophorectomised women

1984 • 48 citations

Peripheral blood flow in menopausal women who have hot flushes and in those who do not.

1989 • 46 citations

Comparison of Continuous Versus Sequential Estrogen and Progestin Therapy in Postmenopausal Women

1991 • 45 citations

Postmenopausal estrogen and androgen replacement and lipoprotein lipid concentrations

1987 • 45 citations

Sex hormones, lipoproteins, and cardiovascular risk

1991 • 44 citations

Oestrogen-induced changes in lipoprotein metabolism: role in prevention of atherosclerosis in the cholesterol-fed rabbit

1989 • 44 citations

Lipid and lipoprotein changes in relation to oral contraception and hormonal replacement therapy.

1988 • 43 citations

Effects of estrogen dose and smoking on lipid and lipoprotein levels in postmenopausal women

1988 • 39 citations

Effects of combined estrogen and progestin administration on plasma lipoprotein metabolism in postmenopausal women.

1989 • 38 citations

Effect on plasma lipids and lipoproteins of postmenopausal oestrogen therapy with added dydrogesterone

1990 • 37 citations

Metabolic regulation of plasma apolipoprotein E by estrogen and progesterone in the baboon (Papio sp)

1991 • 35 citations

Lipid and Lipoprotein Levels following Pure Estradiol Implantation in Post-Menopausal Women

1985 • 34 citations

Cyproterone acetate, an alternative progestogen in postmenopausal hormone replacement therapy? Effects on serum lipids and lipoproteins

1987 • 33 citations

Sodium oleate dissociates the heteroexchange of cholesteryl esters and triacylglycerol between HDL and triacylglycerol-rich lipoproteins

1990 • 28 citations

Hormonal contraceptive increases plasma lipid peroxides in female rats. Relationship to platelet aggregation and lipid biosynthesis.

1989 • 26 citations

Influence of Estrogens on Serum Free Fatty Acid Levels in Women*

1990 • 26 citations

Effect of continuous oestradiol-medroxyprogesterone administration on plasma lipids and lipoproteins

1991 • 25 citations

Hepatic lipase activity during oral and parenteral 17β-estradiol replacement therapy: high-density lipoprotein increase may not be antiatherogenic

1991 • 25 citations

Hormone replacement therapy prevents coronary artery disease in ovariectomized cholesterol‐fed rabbits

1991 • 24 citations

Comparison of two hormone replacement regimens — influence on lipoproteins and bone mineral content

1990 • 19 citations

Estrogen replacement therapy for reduction of cardiovascular risk in women

1991 • 19 citations

Apo A-I metabolism in cynomolgus monkeys: Male-female differences

1990 • 17 citations

A Study of the Hypolipidemic Effect of Estrogen in Type III Hyperlipoproteinemia

1986 • 16 citations

EFFECTS OF TREATMENT WITH OESTRADIOL/LEVONORGESTREL ON BONE, LIPOPROTEINS AND HORMONE STATUS IN POSTMENOPAUSAL WOMEN

1989 • 16 citations

A comparison of the effects of ethinyl estradiol and estradiol valerate on serum and lipoprotein lipids

1988 • 16 citations

Normal but Not Hypertriglyceridemic Very Low-Density Lipoprotein Induces Rapid Release of Tissue Plasminogen Activator from Cultured Human Umbilical Vein Endothelial Cells

1988 • 13 citations

High-dose synthetic progestogens inhibit foam and smooth muscle cell proliferation and atherosclerotic plaque formation in aortas of rabbits fed a hypercholesterolemic diet

1990 • 12 citations

Postmenopausal hormone replacement with a combination estrogen-progestin regimen for five days per week

1991 • 12 citations

Clinical experience with the recently developed progestogens.

1991 • 10 citations

Growth of human aortic smooth muscle cells cultured with human serum is retarded when serum lipids are lowered by medroxyprogesterone

1987 • 6 citations

Progesterone modulates the expression of HDL binding sites in human skin fibroblasts

1988 • 5 citations

1 Approaches to lipid and lipoprotein analysis

1990 • 4 citations

Estrogen in Patients with Prostatic Cancer An Assessment of the Risks and Benefits

1991 • 4 citations

Oral contraceptives and metabolic risk markers for coronary heart disease.

1991 • 2 citations