The significance of oncogene amplification in primary breast cancer

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1984 • 1,153 citations

The neu oncogene encodes an epidermal growth factor receptor-related protein

1986 • 1,131 citations

Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

1988 • 570 citations

EPIDERMAL-GROWTH-FACTOR RECEPTORS AND OESTROGEN RECEPTORS IN HUMAN BREAST CANCER

1985 • 496 citations

OVEREXPRESSION OF THE c-erbB-2 ONCOPROTEIN IN HUMAN BREAST CARCINOMAS: IMMUNOHISTOLOGICAL ASSESSMENT CORRELATES WITH GENE AMPLIFICATION

1987 • 409 citations

Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis.

1987 • 360 citations

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.

1987 • 335 citations

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas.

1983 • 330 citations

Amplification of c- erb B-2 and Aggressive Human Breast Tumors?

1988 • 240 citations

Association of multiple copies of the c-erbB-2 oncogene with spread of breast cancer.

1987 • 214 citations

Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease.

1987 • 143 citations

Prognostic factors for recurrence and survival in human breast cancer

1987 • 138 citations

Relationship between ploidy and steroid hormone receptors in primary invasive breast cancer

1986 • 73 citations

Construction of a map of the short arm of human chromosome 6.

1986 • 48 citations