Prebiotics, Probiotics, and Dietary Fiber in Gastrointestinal Disease

Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics

1995 • 7,436 citations

Probiotics in man and animals

1989 • 4,002 citations

Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial

2000 • 1,505 citations

Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles

2005 • 1,398 citations

Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine

2004 • 1,213 citations

Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial

2003 • 1,139 citations

Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial

1999 • 1,106 citations

Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study

2003 • 1,101 citations

Lack of Effect of a Low-Fat, High-Fiber Diet on the Recurrence of Colorectal Adenomas

2000 • 943 citations

Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis

2003 • 905 citations

The Prolongation of Life: Optimistic Studies

2003 • 889 citations

Meta-Analysis of Probiotics for the Prevention of Antibiotic Associated Diarrhea and the Treatment of Clostridium difficile Disease

2006 • 848 citations

Low-Fat Dietary Pattern and Risk of Invasive Breast Cancer

2006 • 826 citations

Lack of Effect of a High-Fiber Cereal Supplement on the Recurrence of Colorectal Adenomas

2000 • 809 citations

Double‐blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitis

1997 • 780 citations

Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35624 in Women with Irritable Bowel Syndrome

2006 • 769 citations

Treatment of Diversion Colitis with Short-Chain-Fatty Acid Irrigation

1989 • 764 citations

Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis

1992 • 737 citations

VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative Colitis

2005 • 723 citations

Dietary Fiber and the Risk of Colorectal Cancer and Adenoma in Women

1999 • 701 citations

Saccharomyces boulardii in maintenance treatment of Crohn's disease.

2000 • 698 citations

Prebiotic digestion and fermentation

2001 • 641 citations

Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: A prospective study

1989 • 581 citations

Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis

1999 • 572 citations

Ineffectiveness of probiotics in preventing recurrence after curative resection for Crohn's disease: a randomised controlled trial with Lactobacillus GG

2002 • 564 citations

Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome

2000 • 544 citations

RecurrentClostridium difficileColitis: Case Series Involving 18 Patients Treated with Donor Stool Administered via a Nasogastric Tube

2003 • 515 citations

Alteration of Intestinal Microflora Is Associated With Reduction in Abdominal Bloating and Pain in Patients With Irritable Bowel Syndrome

2000 • 509 citations

A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome

2001 • 496 citations

A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea‐predominant irritable bowel syndrome

2003 • 469 citations

Dietary Fiber Intake and Risk of Colorectal Cancer

2005 • 458 citations

Dietary Fiber and Disease

1974 • 457 citations

Efficacy of Lactobacillus GG in maintaining remission of ulcerative colitis

2006 • 449 citations

21-TRISOMY/NORMAL MOSAICISM IN AN INTELLIGENT CHILD WITH SOME MONGOLOID CHARACTERS

1963 • 438 citations

Is Lactobacillus GG Helpful in Children With Crohn’s Disease? Results of a Preliminary, Open-Label Study

2000 • 431 citations

Diverticular Disease of the Colon, a 20th Century Problem

1975 • 422 citations

Postmortem survey of diverticular disease of the colon. I. Diverticulosis and diverticulitis.

1969 • 414 citations

Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease: a randomised, double blind, placebo controlled GETAID trial

2005 • 409 citations

Crohn's Disease and Escherichia coli

1997 • 405 citations

COLONIC RESPONSE TO DIETARY FIBRE FROM CARROT, CABBAGE, APPLE, BRAN, AND GUAR GUM

1978 • 404 citations

Low-Fat Dietary Pattern and Risk of Colorectal Cancer

2006 • 399 citations

Risk Factors for Fatal Colon Cancer in a Large Prospective Study

1992 • 397 citations

Pharmacologic Treatment of the Irritable Bowel Syndrome

2000 • 393 citations

Pouchitis and extraintestinal manifestations of inflammatory bowel disease after ileal pouch-anal anastomosis.

1990 • 392 citations

Treatment of Ulcerative Colitis Using Fecal Bacteriotherapy

2003 • 386 citations

Randomized placebo‐controlled trial assessing the effect of bifidobacteria‐fermented milk on active ulcerative colitis

2004 • 379 citations

Gastrointestinal and liver disease

1979 • 371 citations

A pilot trial of Saccharomyces boulardii in ulcerative colitis

2003 • 369 citations

A Randomized, Double-blind Trial of Lactobacillus GG Versus Placebo in Addition to Standard Maintenance Therapy for Children with Crohnʼs Disease

2005 • 355 citations

CHRONIC ENTEROVIRUS INFECTION IN PATIENTS WITH POSTVIRAL FATIGUE SYNDROME

1988 • 344 citations

Randomized Trial of Intake of Fat, Fiber, and Beta Carotene to Prevent Colorectal Adenomas

1995 • 331 citations

Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme

2003 • 330 citations

A prospective study of diet and the risk of symptomatic diverticular disease in men

1994 • 322 citations

RELATED DISEASE—RELATED CAUSE?

1969 • 314 citations

Probiotics A critical review

1999 • 310 citations

Diverticular Disease of the Colon

1980 • 306 citations

Short chain fatty acid rectal irrigation for left-sided ulcerative colitis: a randomised, placebo controlled trial.

1997 • 268 citations

Introduction to intestinal microecology

1972 • 265 citations

Pouchitis following pelvic pouch operation for ulcerative colitis

1996 • 264 citations

Bacterial supplementation in the irritable bowel syndrome. A randomised doubleblind placebo-controlled crossover study

2000 • 245 citations

Low-dose balsalazide plus a high-potency probiotic preparation is more effective than balsalazide alone or mesalazine in the treatment of acute mild-to-moderate ulcerative colitis.

2004 • 236 citations

Effects of Lactulose and Lactitol on Colonic Microflora and Enzymatic Activity

1997 • 233 citations

Gastrointestinal effects of food carbohydrate

1995 • 229 citations

Effect of the Prebiotic Oligofructose on Relapse of Clostridium difficile-Associated Diarrhea: A Randomized, Controlled Study

2005 • 223 citations

TREATMENT OF SYMPTOMATIC DIVERTICULAR DISEASE WITH A HIGH-FIBRE DIET

1977 • 223 citations

Combination of antibiotic and probiotic treatment is efficacious in prophylaxis of post-operative recurrence of Crohn's disease: A randomized controlled study VS mesalamine

2000 • 213 citations

Probiotic therapy for the prevention and treatment of Clostridium difficile-associated diarrhea: a systematic review

2005 • 210 citations

Unprocessed Bran in Treatment of Diverticular Disease of the Colon

1972 • 206 citations

Whole grain consumption and risk of colorectal cancer: a population-based cohort of 60 000 women

2005 • 205 citations

EFFECTS OF UNPROCESSED BRAN ON COLON FUNCTION IN NORMAL SUBJECTS AND IN DIVERTICULAR DISEASE

1974 • 203 citations

Gastrointestinal and liver disease

2019 • 203 citations

A randomized trial of a low fat high fibre diet in the recurrence of colorectal polyps

1994 • 184 citations

Treatment of recurrent Clostridium difficile-associated diarrhea by administration of donated stool directly through a colonoscope

2000 • 176 citations

Maintenance therapy with a probiotic in antibiotic‐dependent pouchitis: experience in clinical practice

2005 • 175 citations

Refined Carbohydrate Foods and Disease: Some Implications of Dietary Fibre

1976 • 173 citations

Probiotics in The Treatment of Irritable Bowel Syndrome

2004 • 173 citations

Lactulose in the Treatment of Chronic Portal-Systemic Encephalopathy

1969 • 172 citations

Dietary fiber in human nutrition

1975 • 171 citations

Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea--a pilot study.

1993 • 170 citations

Combining wheat bran with resistant starch has more beneficial effects on fecal indexes than does wheat bran alone

2004 • 160 citations

Metabolic induction of experimental ulcerative colitis by inhibition of fatty acid oxidation.

1986 • 140 citations

Treatment of ulcerative colitis patients by long-term administration of germinated barley foodstuff: Multi-center open trial

2003 • 132 citations

Efficacy, safety, and tolerability of fructooligosaccharides in the treatment of irritable bowel syndrome

2000 • 131 citations

Dietary fibre for the prevention of colorectal adenomas and carcinomas

2002 • 127 citations

Bran tablets and diverticular disease.

1976 • 121 citations

Diverticular disease of the colon.

1968 • 120 citations

The effect of non-pathogenic Escherichia coli in symptomatic uncomplicated diverticular disease of the colon.

2003 • 103 citations

Oral contraceptives, venous thromboembolic disease, and ABO blood type

1971 • 102 citations

Controlled Trial of Oligofructose in the Management of Irritable Bowel Syndrome

1999 • 100 citations

Cereal dietary fiber consumption and diverticular disease: a lifespan study in rats

1985 • 98 citations

Modification of Intestinal Flora in the Treatment of Inflammatory Bowel Disease

2003 • 98 citations

Probiotics for ulcerative colitis therapy Rembacken BJ, Snelling AM, Hawkey PM, et al. Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: A randomized trial. Lancet 1999;354:635–9.

2000 • 96 citations

The effect of non-pathogenic Escherichia coli in symptomatic uncomplicated diverticular disease of the colon

2003 • 94 citations

Recommendations for Probiotic Use

2006 • 93 citations

Dietary fiber and disease

1974 • 93 citations

Dietary fibre, fibre-depleted foods and disease

1985 • 93 citations

Lactobacillus Acidophilus and Its Therapeutic Application.

1936 • 92 citations

Probiotics and Prebiotics: Where Are We Going?

2003 • 89 citations

Dietary fibre, fibre depleted foods and disease

1986 • 84 citations

Classification and methodology of food carbohydrates as related to nutritional effects

1995 • 73 citations

Case Closed?

2006 • 67 citations

Probiotics Used in Human Studies

2005 • 63 citations

Probiotics. A critical review

1999 • 59 citations

The cause of diverticular disease of the colon, its symptoms and its complications. Review and hypothesis.

1985 • 49 citations

Use of Probiotics in Humans: An Analysis of the Literature

2005 • 44 citations

Diet in the Irritable Bowel Syndrome

2002 • 42 citations

Vegetarianism, Dietary Fibre and Gastro-lntestinal Disease

1994 • 40 citations

Dietary fibre and gastrointestinal disease

1988 • 33 citations

Probiotic therapy with E. coli for ulcerative colitis: Take the good with the bad

2000 • 28 citations

Prebiotic oligosaccharides: evaluation of biological activities and potential future developments

2002 • 28 citations

LACTOBACILLUS ACIDOPHILUS AND ITS THERAPEUTIC APPLICATION

1936 • 22 citations

Lactobacillus Acidophilus.

1926 • 22 citations

Netter??s Gastroenterology

2005 • 22 citations

Probiotics and Prebiotics, Where Are We Going?

2003 • 21 citations

The saccharine disease.

1975 • 19 citations

Netter's Gastroenterology

2005 • 16 citations

Clinical Nutrition in Gastrointestinal Disease

2024 • 11 citations

Clinical Nutrition in Gastrointestinal Disease

2007 • 9 citations

Prebiotics, Probiotics, and Dietary Fiber

2024 • 7 citations

Indications for percutaneous gastrostomy (jejunostomy) (PEG/J).

1990 • 5 citations

Manipulation of colonic flora as ecosystem and metabolic organ: Consequences for the organism - Preface

1997 • 5 citations