Pharmacologic Treatment of the Irritable Bowel Syndrome

Improving the quality of reporting of randomized controlled trials. The CONSORT statement

1996 • 3,395 citations

U. S. Householder survey of functional gastrointestinal disorders

1993 • 2,195 citations

Systematic Reviews: Synthesis of Best Evidence for Clinical Decisions

1997 • 2,082 citations

Summing up: The Science of Reviewing Research

1987 • 1,530 citations

A method for assessing the quality of a randomized control trial

1981 • 1,370 citations

meta-analysis bias in location and selection of studies

1998 • 1,311 citations

Best evidence synthesis: An intelligent alternative to meta-analysis

1995 • 893 citations

Developing Optimal Search Strategies for Detecting Clinically Sound Studies in MEDLINE

1994 • 779 citations

Irritable bowel syndrome: A technical review for practice guideline development

1997 • 585 citations

Methodologic guidelines for systematic reviews of randomized control trials in health care from the potsdam consultation on meta-analysis

1995 • 581 citations

Treatment of Irritable Bowel Syndrome With Chinese Herbal Medicine

1998 • 409 citations

Meta‐analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome

2001 • 398 citations

Controlled treatment trials in the irritable bowel syndrome: A critique

1988 • 392 citations

Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT₃ receptor antagonist

1999 • 381 citations

The Irritable Bowel Syndrome: Long-Term Prognosis and the Physician-Patient Interaction

1995 • 351 citations

Irritable Bowel Syndrome in a Community: Symptom Subgroups, Risk Factors, and Health Care Utilization

1995 • 341 citations

The Irritable Bowel Syndrome: Review and a Graduated Multicomponent Treatment Approach

1992 • 322 citations

Irritable bowel syndrome in office-based practice in the United States

1991 • 316 citations

Role of loperamide and placebo in management of irritable bowel syndrome (IBS)

1984 • 257 citations

Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: A prospective, randomized trial

1997 • 210 citations

A Double-Blind Placebo-Controlled Trial with Loperamide in Irritable Bowel Syndrome

1996 • 201 citations

Influence of antidepressants on whole gut and orocaecal transit times in health and irritable bowel syndrome

1994 • 197 citations

Evaluation of a new quality of life questionnaire for patients with irritable bowel syndrome

1997 • 190 citations

Patient‐perceived severity of irritable bowel syndrome in relation to symptoms, health resource utilization and quality of life

1997 • 183 citations

Effects of desipramine on irritable bowel syndrome compared with atropine and placebo

1987 • 182 citations

Loperamide in Treatment of Irritable Bowel Syndrome—A Double-Blind Placebo Controlled Study

1987 • 170 citations

Treatment of irritable bowel syndrome with lorazepam, hyoscine butylbromide, and ispaghula husk.

1979 • 163 citations

Functional bowel disorders

1995 • 163 citations

Efficacy of peripheral kappa agonist fedotozine versus placebo in treatment of irritable bowel syndrome

1995 • 158 citations

Psychological treatments for irritable bowel syndrome: a critique of controlled treatment trials.

1996 • 154 citations

Is bran efficacious in irritable bowel syndrome? A double blind placebo controlled crossover study.

1987 • 151 citations

A DOUBLE-BLIND TRIAL OF THE EFFECT OF WHEAT BRAN ON SYMPTOMS OF IRRITABLE BOWEL SYNDROME

1976 • 145 citations

Loperamide Treatment of the Irritable Bowel Syndrome

1987 • 142 citations

The Irritable Bowel Syndrome: Mechanisms and a Practical Approach to Management

1992 • 135 citations

Treatment of the Irritable Bowel Syndrome with Bentyl® (Dicyclomine Hydrochloride)

1981 • 129 citations

Effect of a tricyclic antidepressant on small intestinal motility in health and diarrhea-predominant irritable bowel syndrome

1995 • 121 citations

A Double-Blind Study of the Effect of Trimipramine in Patients with the Irritable Bowel Syndrome

1984 • 116 citations

Comparison of the Therapeutic Effect of Wheat Bran, Mebeverine and Placebo in Patients with the Irritable Bowel Syndrome

1986 • 114 citations

Selective 5-Hydroxytryptamine Type 3 Receptor Antagonism With Ondansetron as Treatment for Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study

1992 • 106 citations

Bran supplementation in the treatment of irritable bowel sgndrome

1994 • 106 citations

Psyllium Therapy in the Irritable Bowel Syndrome

1981 • 99 citations

“Prokinetic” Treatment of Constipation-Predominant Irritable Bowel Syndrome

1991 • 99 citations

Effect of dietary fiber on symptoms and rectosigmoid motility in patients with irritable bowel syndrome

1990 • 97 citations

Selective 5‐hydroxytryptamine antagonism: a role in irritable bowel syndrome and functional dyspepsia?

1996 • 97 citations

Symptom relief with amitriptyline in the Irritable Bowel syndrome

1998 • 94 citations

A Clinical Trial of Trimebutine (Mebutin) in Spastic Colon

1979 • 92 citations

Short-Chain Fatty Acids and the Irritable Bowel Syndrome: The Effect of Wheat Bran

1987 • 88 citations

Influence of drug treatment on the irritable bowel syndrome and its interaction with psychoneurotic morbidity

1982 • 83 citations

Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acidophilus milk

1983 • 82 citations

Peppermint oil does not relieve the pain of irritable bowel syndrome

1986 • 77 citations

Paraghurt for Patients with Irritable Bowel Syndrome:A Controlled Clinical Investigation from General Practice

1989 • 72 citations

Double‐blind cross‐over trial of oral sodium cromoglycate in patients with irritable bowel syndrome due to food intolerance

1991 • 72 citations

Longterm treatment of irritable bowel syndrome with cimetropium bromide: a double blind placebo controlled clinical trial.

1990 • 68 citations

Therapeutic Usefulness of Amitriptyline in Spastic Colon Syndrome

1982 • 66 citations

Effect of leuprolide acetate in treatment of abdominal pain and nausea in premenopausal women with functional bowel disease: a double-blind, placebo-controlled, randomized study.

1998 • 64 citations

Double‐blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome

1997 • 60 citations

Ispaghula therapy in irritable bowel syndrome: Improvement in overall well‐being is related to reduction in bowel dissatisfaction

1990 • 57 citations

The Symptomatic Effect of Cisapride in Patients with Irritable Bowel Syndrome and Constipation

1998 • 53 citations

Oral cimetropium bromide, a new antimuscarinic drug, for long-term treatment of irritable bowel syndrome.

1988 • 53 citations

Oral domperidone: double blind comparison with placebo in irritable bowel syndrome.

1983 • 52 citations

Irritable bowel syndrome: therapeutic evaluation of indigenous drugs.

1989 • 50 citations

Mebeverine in patients with the irritable colon syndrome: double blind study.

1973 • 50 citations

Use of the peripheral dopamine antagonist, domperidone, in the management of gastrointestinal symptoms in patients with irritable bowel syndrome

1980 • 49 citations

Double blind trial of ispaghula/poloxamer in the Irritable Bowel Syndrome.

1983 • 43 citations

Prifinium bromide in the treatment of the irritable colon syndrome

1979 • 42 citations

Effect of leuprolide acetate in patients with functional bowel disease

1994 • 41 citations

Irritable bowel syndrome treatment using pinaverium bromide as a calcium channel blocker. A randomized double-blind placebo-controlled trial.

1995 • 38 citations

A Controlled Therapeutic Study of the Irritable-Bowel Syndrome

1973 • 35 citations

Investigations on caffeine passage into the canine gastric juice.

1991 • 33 citations

Use of oral sodium cromoglycate in persistent diarrhoea.

1980 • 33 citations

Domperidone Treatment in the Irritable Bowel Syndrome

1982 • 32 citations

Failure of enteric‐coated peppermint oil in the irritable bowel syndrome: A randomized, double‐blind crossover study

1988 • 31 citations

Loxiglumide, a CCK‐A Antagonist, in Irritable Bowel Syndrome

1994 • 30 citations

Timolol Treatment in the Irritable Bowel Syndrome

1981 • 22 citations

Controlled Clinical Trial of Mepiprazole in Irritable Bowel Syndrome

1974 • 21 citations

Double‐blind study of an α₂ agonist in the treatment of irritable bowel syndrome

1988 • 20 citations

Role of ispaghula husk in the management of irritable bowel syndrome (a randomized double-blind crossover study).

1982 • 20 citations

The non-effect of pirenzepine in dietary resistant irritable bowel syndrome

1989 • 16 citations

Diltiazem in the treatment of the irritable bowel syndrome.

1986 • 15 citations

Comparative effect of phenaglycodol, meprobamate, and a placebo on the irritable colon

1959 • 14 citations

An Approach to the Design of Therapeutic Trials in IBS

1987 • 8 citations

A double blind crossover study of diphenylhydantoin in irritable bowel syndrome.

1983 • 6 citations

Deleted Work

1955 • 0 citations