Cytolytic and ion channel-forming properties of the N terminus of lymphocyte perforin.

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)

1980 • 1,491 citations

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

The structure of melittin in the form I crystals and its implication for melittin's lytic and surface activities

1982 • 410 citations

Structure and function of human perforin

1988 • 346 citations

Extracellular ATP as a trigger for apoptosis or programmed cell death.

1991 • 342 citations

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

1986 • 316 citations

The Ninth Component of Complement and the Pore-Forming Protein (Perforin 1) from Cytotoxic T Cells: Structural, Immunological, and Functional Similarities

1986 • 272 citations

Homology of perforin to the ninth component of complement (C9)

1988 • 268 citations

Secondary structure of a channel-forming protein: porin from E. coli outer membranes.

1985 • 160 citations

Killing of target cells by lymphocytes: a mechanistic view.

1989 • 134 citations

Phosphorylcholine acts as a Ca2+-dependent receptor molecule for lymphocyte perforin

1989 • 114 citations

Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.

1989 • 110 citations

Cytotoxic T lymphocyte mediated cytolysis

1988 • 99 citations

Design and characterization of peptides with amphiphilic β‐strand structures

1985 • 98 citations

Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors.

1984 • 95 citations

Alamethicin and related membrane channel forming polypeptides

1983 • 83 citations

Perforin-mediated myocardial damage in acute myocarditis

1990 • 81 citations

Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin).

1987 • 73 citations

[25] Structure-function analysis of proteins through the design, synthesis, and study of peptide models

1987 • 64 citations

The structure of the mouse lymphocyte pore-forming protein perforin

1989 • 58 citations

A family of killer proteins

1988 • 51 citations

Resistance of cytolytic lymphocytes to perforin-mediated killing. Inhibition of perforin binding activity by surface membrane proteins.

1990 • 47 citations

Inhibition of the lytic activity of perforin by lipoproteins.

1986 • 35 citations

How do cytotoxic T lymphocytes avoid self-lysis?

1988 • 24 citations

Cell-mediated killing: effector mechanisms and mediators.

1990 • 17 citations

Characterization of the inhibitory effect of lysolipids on perforin-mediated hemolysis

1990 • 13 citations