How do cytotoxic T lymphocytes avoid self-lysis?

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

A novel serine esterase expressed by cytotoxic T lymphocytes

1985 • 319 citations

Mechanism of Specific Tumor-Cell Lysis by Alloimmune T Lymphocytes: Resolution and Characterization of Discrete Steps in the Cellular Interaction

1977 • 258 citations

Homologous species restriction in lysis of human erythrocytes: a membrane-derived protein with C8-binding capacity functions as an inhibitor.

1986 • 241 citations

Serine esterase in cytolytic T lymphocytes

1986 • 240 citations

The molecular mechanism of lymphocyte-mediated tumor cell lysis

1985 • 183 citations

Isolation and characterization of a serine esterase from cytolytic T cell granules

1986 • 177 citations

Granules of cytolytic T-lymphocytes contain two serine esterases.

1986 • 148 citations

Cytotoxic T‐Lymphocytes How Do They Function?

1983 • 124 citations

On the mechanism of unidirectional killing in mixtures of two cytotoxic T lymphocytes. Unidirectional polarization of cytoplasmic organelles and the membrane-associated cytoskeleton in the effector cell.

1986 • 122 citations

Identification, isolation, and characterization of a novel cytotoxin in murine cytolytic lymphocytes

1987 • 113 citations

Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes.

1986 • 112 citations

Cellular and Humoral Mechanisms of Cytotoxicity: Structural and Functional Analogies

1987 • 111 citations

Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity.

1987 • 89 citations

Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity

1974 • 70 citations

MULTIPLE TARGET CELL KILLING BY THE CYTOLYTIC T LYMPHOCYTE AND THE MECHANISM OF CYTOTOXICITY

1976 • 66 citations

Studies on the mechanism of lymphocyte-mediated cytolysis. IX. Relationships between antigen recognition and lytic expression in killer T cells.

1977 • 62 citations

Evidence for direct linkage between antigen recognition and lytic expression in effector T cells.

1976 • 53 citations

The most efficient cytotoxic T lymphocytes are the least susceptible to lysis.

1987 • 41 citations

T Lymphocyte-Mediated Cytolysis: Dissociation of the Binding and Lytic Mechanisms of the Effector Cell

1978 • 40 citations

Lytic Activity of C5̄‑9̄ Complexes for Erythrocytes from the Species Other Than Sheep: C9 Rather Than C8-Dependent Variation in Lytic Activity

1977 • 38 citations

Studies on the Mechanism of Lymphocyte-Mediated Cytolysis

1977 • 36 citations

Self-sparing of long-term in vitro-cloned or uncloned cytotoxic T lymphocytes.

1986 • 32 citations