Altered microvascular reactivity to endothelin‐1, endothelin‐3 and N^G‐nitro‐L‐arginine methyl ester in streptozotocin‐induced diabetes mellitus

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide.

1990 • 1,066 citations

<scp>l</scp>‐N^G‐nitro arginine (<scp>l</scp>‐NOARG), a novel, <scp>l</scp>‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro

1990 • 769 citations

Elevated plasma endothelin in patients with diabetes mellitus

1990 • 492 citations

Studies of streptozotocin-induced insulitis and diabetes.

1977 • 262 citations

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

1989 • 260 citations

Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus

1989 • 174 citations

Skeletal Muscle Capillaries in Diabetics

1970 • 133 citations

Direct Vital Microscopic Study of Defective Leukocyte-Endothelial Interaction in Diabetes Mellitus

1991 • 107 citations

Production of endothelin-1 from the mesenteric arteries of streptozotocin-induced diabetic rats

1991 • 98 citations

Endothelial cell function in diabetic microangiopathy

1987 • 97 citations

The effects of endothelin‐1 and N^G‐nitro‐<scp>l</scp>‐arginine methyl ester on regional haemodynamics in conscious rats with streptozotocin‐induced diabetes mellitus

1991 • 89 citations

Inhibition of Leukocyte Chemotaxis by Factor in Alloxan-Induced Diabetic Rat Plasma

1987 • 87 citations

Selective impairment of hindquarters vasodilator responses to bradykinin in conscious Wistar rats with streptozotocin‐induced diabetes mellitus

1991 • 83 citations

Structural and functional origins of suppressed acetylcholine vasodilation in diabetic rat intestinal arterioles.

1991 • 83 citations

Vascular reactivity in diabetes mellitus: possible role of insulin on the endothelial cell

1984 • 72 citations

Microcirculation and diabetes

1989 • 70 citations

Antiarrhythmic properties of tedisamil (KC8857), a putative transient outward K⁺ current blocker

1991 • 64 citations

Influence of diabetes on the reactivity of mesenteric microvessels to histamine, bradykinin and acetylcholine

1983 • 63 citations

Influence of diabetes upon the inflammatory response of the rat. A pharmacological analysis

1973 • 63 citations

Inhibition of leukocyte chemotaxis by serum factor in diabetes mellitus: Selective depression of cell responses mediated by complement-derived chemoattractants

1990 • 55 citations

Angiotensin II and phorbol-esters potently down-regulate endothelin (ET-1) binding sites in vascular smooth muscle cells

1989 • 55 citations

Arteriolar anatomical and functional abnormalities in juvenile mice with genetic or streptozotocin-induced diabetes mellitus.

1979 • 54 citations

Early increase in CGRP- and VIP-immunoreactive nerves in the skin of streptozotocin-induced diabetic rats

1990 • 52 citations

Regional Hemodynamic Effects of Endothelin-1 in Conscious, Unrestrained, Wistar Rats

1989 • 51 citations

Possible participation of insulin in the control of vascular permeability

1974 • 46 citations

Skeletal Muscle Capillaries in Nondiabetics

1970 • 45 citations

Endothelin-1 in Human Skin: Immunolocalization, Receptor Binding, mRNA Expression, and Effects on Cutaneous Microvascular Endothelial Cells

1991 • 43 citations

Alterations in distribution of cardiac output in experimental diabetes in rats

1989 • 39 citations

Inhibition of leukocyte chemotaxis by factor in alloxan-induced diabetic rat plasma

1987 • 37 citations

Responses to endothelins in the rat cutaneous microvasculature: a modulatory role of locally‐produced nitric oxide

1992 • 34 citations

Streptozotocin‐induced diabetes reduces the density of [¹²⁵I]‐endothelin‐binding sites in rat cardiac membranes

1989 • 29 citations

Effect of Endothelin-1 on Arterioles and Venules in vivo

1989 • 28 citations

Role of endothelin in mechanisms of local blood pressure control.

1990 • 14 citations

The effect of 4-week streptozotocin-induced diabetes on responses to endothelin-1 in rat isolated atria

1991 • 3 citations