Specificity of Hypothalamic Peptides in the Control of Behavioral and Physiological Processes

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

1982 • 2,244 citations

Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei

1983 • 1,962 citations

Galanin — a novel biologically active peptide from porcine intestine

1983 • 1,480 citations

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

1984 • 1,274 citations

Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity

1986 • 856 citations

Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food.

1991 • 678 citations

Metabolic fuels and reproduction in female mammals

1992 • 677 citations

Neuroreptide Y: Stimulation of feeding and drinking by injection into the paraventricular nucleus

1984 • 666 citations

Altered Expression of Hypothalamic Neuropeptide mRNAs in Food-Restricted and Food-Deprived Rats

1990 • 648 citations

Neuropeptide Y: A potent inducer of consummatory behavior in rats

1984 • 564 citations

An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat

1985 • 523 citations

Mapping of Glucocorticoid Receptor Immunoreactive Neurons in the Rat Tel- and Diencephalon Using a Monoclonal Antibody against Rat Liver Glucocorticoid Receptor*

1985 • 512 citations

Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus

1988 • 510 citations

Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity.

1993 • 466 citations

Neuropeptide Y Stimulates Feeding but Inhibits Sexual Behavior in Rats*

1985 • 397 citations

The hypothalamus, intrinsic connections and outflow pathways to the endocrine system in relation to the control of feeding and metabolism

1987 • 394 citations

Effects of glucocorticoids on carbohydrate metabolism

1988 • 391 citations

Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion

1985 • 386 citations

Neuropeptide Y-Related Peptides and their Receptors--Are the Receptors Potential Therapeutic Drug Targets?

1993 • 380 citations

Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues

1992 • 379 citations

Anatomy and physiology of central galanin-containing pathways

1993 • 340 citations

Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.

1988 • 318 citations

Increased Hypothalamic Content of Preproneuropeptide Y Messenger Ribonucleic Acid in Genetically Obese Zucker Rats and Its Regulation by Food Deprivation*

1990 • 312 citations

Rapid membrane effects of steroid hormones: an emerging concept in neuroendocrinology

1990 • 306 citations

Food preferences in human obesity: Carbohydrates versus fats

1992 • 301 citations

Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effect

1992 • 288 citations

Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat

1987 • 285 citations

Stimulation of feeding by galanin: Anatomical localization and behavioral specificity of this peptide's effects in the brain

1990 • 253 citations

Effects of PVN galanin on macronutrient selection

1988 • 252 citations

The perifornical area: the major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s)

1993 • 250 citations

CENTRAL INSULIN ADMINISTRATION REDUCES NEUROPEPTIDE Y mRNA EXPRESSION IN THE ARCUATE NUCLEUS OF FOOD-DEPRIVED LEAN (Fa/Fa) BUT NOT OBESE (fa/fa) ZUCKER RATS

1991 • 244 citations

Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status

1990 • 243 citations

Modulation of memory processing by neuropeptide Y

1987 • 222 citations

Hypothalamic paraventricular nucleus: Interaction between α2-noradrenergic system and circulating hormones and nutrients in relation to energy balance

1988 • 210 citations

Comparison of stress response in male and female rats: Pituitary cyclic AMP and plasma prolactin, growth hormone and corticosterone

1983 • 208 citations

Increased hypothalamic neuropeptide Y expression following food deprivation

1990 • 193 citations

Increased Neuropeptide Y Concentrations in Specific Hypothalamic Regions of Streptozocin-Induced Diabetic Rats

1989 • 186 citations

Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism

1992 • 185 citations

A chronometric approach to the study of feeding behavior

1980 • 181 citations

Specific inhibition of endogenous neuropeptide Y synthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behavior and insulin secretion

1994 • 180 citations

Increased Hypothalamic Content of Preproneuropeptide-Y Messenger Ribonucleic Acid in Streptozotocin-Diabetic Rats*

1990 • 180 citations

Organization of galanin‐immunoreactive inputs to the paraventricular nucleus with special reference to their relationship to catecholaminergic afferents

1987 • 177 citations

Activity of centrally administered galanin fragments on stimulation of feeding behavior and on galanin receptor binding in the rat hypothalamus

1990 • 168 citations

Galanin Inhibits Insulin Secretion and Induces Hyperglycemia in Dogs

1985 • 162 citations

Effects of neuropeptide Y, NPY analog (norleucine4-NPY), galanin and neuropeptide K on LH release in ovariectomized (ovx) and ovx estrogen, progesterone-treated rats

1987 • 158 citations

Analysis of neuropeptide Y-induced feeding: Dissociation of Y1 and Y2 receptor effects on natural meal patterns

1991 • 149 citations

Diurnal rhythm of neuropeptide Y-like immunoreactivity in the suprachiasmatic, arcuate and paraventricular nuclei and other hypothalamic sites

1990 • 130 citations

Galanin Antagonists Block Galanin‐induced Feeding in the Hypothalamus and Amygdala of the Rat

1993 • 129 citations

Neuropeptide-Y Concentration in Microdissected Hypothalamic Regions andin VitroRelease from the Medial Basal Hypothalamus-Preoptic Area of Streptozotocin-Diabetic Rats with and without Insulin Substitution Therapy*

1990 • 128 citations

Neuropeptide Y projection from arcuate nucleus to parvocellular division of paraventricular nucleus: specific relation to the ingestion of carbohydrate

1993 • 126 citations

Localization of Neuropeptide-Y Immunoreactivity in Estradiol-Concentrating Cells in the Hypothalamus*

1990 • 126 citations

Increased Hypothalamic Neuropeptide Y Concentrations in Diabetic Rat

1988 • 120 citations

Neuropeptide Y release from the paraventricular nucleus increases in association with hyperphagia in streptozotocin-induced diabetic rats.

1992 • 115 citations

Neuropeptide Y gene expression in the arcuate nucleus: sexual dimorphism and modulation by testosterone.

1993 • 114 citations

Altered Neuropeptide Y Concentrations in Specific Hypothalamic Regions of Obese (fa/fa) Zucker Rats: Possible Relationship to Obesity and Neuroendocrine Disturbances

1991 • 114 citations

Effects of Ovarian Hormones on the Concentrations of Immunoreactive Neuropeptide Y in Discrete Brain Regions of the Female Rat: Correlation with Serum Luteinizing Hormone (LH) and Median Eminence LH-Releasing Hormone*

1985 • 113 citations

Impact of a galanin antagonist on exogenous galanin and natural patterns of fat ingestion

1992 • 112 citations

Sexual Differences in the Distribution of Neurons Coexpressing Galanin and Luteinizing Hormone- Releasing Hormone in the Rat Brain

1991 • 109 citations

Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: Effects of adrenalectomy and cholecystokinin

1988 • 106 citations

Ontogeny of a novel peptide, neuropeptide Y (NPY) in rat brain

1984 • 98 citations

Suppression of neuropeptide Y-elicited eating by adrenalectomy or hypophysectomy: reversal with corticosterone

1989 • 96 citations

Hypothalamic Neuropeptide Y and Its Gene Expression: Relation to Light/Dark Cycle and Circulating Corticosterone

1994 • 95 citations

Metabolic effects of neuropeptide Y injections into the paraventricular nucleus of the hypothalamus

1990 • 94 citations

Galaninergic Mechanisms Are Involved in the Regulation of Corticotropin and Thyrotropin Secretion in the Rat*

1990 • 89 citations

Neuropeptide Y in the arcuate nucleus is modulated by alterations in glucose utilization

1993 • 88 citations

Role of galanin in stimulation of pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide.

1994 • 85 citations

Effect of fasting on regional levels of neuropeptide Y mRNA and insulin receptors in the rat hypothalamus: An autoradiographic study

1992 • 84 citations

A Physiological Role for Neuropeptide Y in Regulating the Estrogen/Progesterone Induced Luteinizing Hormone Surge in Ovariectomized Rats

1989 • 83 citations

Steroidal regulation of hypothalamic neuropeptide Y release and gene expression.

1992 • 83 citations

Central peptidergic neurons as targets for glucocorticoid action. Evidence for the presence of glucocorticoid receptor immunoreactivity in various types of classes of peptidergic neurons

1991 • 82 citations

Development of the neuronal system containing neuropeptide Y in the rat hypothalamus

1989 • 80 citations

Estrogen-concentrating cells within cell groups of the medial preoptic area: sex differences and co-localization with galanin-immunoreactive cells

1992 • 80 citations

Galanin-Like Immunoreactivity Is Influenced by Estrogen in Peripubertal and Adult Rats

1990 • 79 citations

Endogenous galanin modulates the gonadotropin and prolactin proestrous surges in the rat.

1993 • 79 citations

Injection of anti-neuropeptide Y γ-globulin into the hypothalamic paraventricular nucleus decreases food intake in rats

1993 • 78 citations

Glucocorticoids are Required for Food Deprivation‐Induced Increases in Hypothalamic Neuropeptide Y Expression

1992 • 77 citations

Effects of varying the carbohydrate: fat ratio in a hot lunch on postprandial variables in male volunteers

1989 • 77 citations

Tissue-specific sex differences in galanin-like immunoreactivity and galanin mRNA during development in the rat

1989 • 74 citations

Dexamethasone treatment increases neuropeptide Y levels in rat hypothalamic neurones

1988 • 74 citations

Increases in Neuropeptide Y Content and Gene Expression in the Hypothalamus of Rats Treated with Dexamethasone Are Prevented by Insulin

1993 • 72 citations

NEUROPEPTIDE Y (NPY): A POSSIBLE ROLE IN THE INITIATION OF PUBERTY

1988 • 70 citations

Rat Vasopressin Response to Insulin-Induced Hypoglycemia*

1980 • 69 citations

Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat.

1993 • 68 citations

Testosterone Raises Neuropeptide-Y Concentration in Selected Hypothalamic Sites andin VitroRelease from the Medial Basal Hypothalamus of Castrated Male Rats*

1989 • 66 citations

Galanin in the hypothalamus of fed and fasted lean and obese Zucker rats

1993 • 62 citations

Neuropeptide Y gene expression in the arcuate nucleus is increased during preovulatory luteinizing hormone surges.

1992 • 62 citations

Insulin deficiency is a specific stimulus to hypothalamic neuropeptide Y: A comparison of the effects of insulin replacement and food restriction in streptozocin-diabetic rats

1992 • 61 citations

Food deprivation and age modulate neuropeptide gene expression in the murine hypothalamus and adrenal gland

1991 • 58 citations

Increased neuropeptide Y content in the arcuato-paraventricular hypothalamic neuronal system in both insulin-dependent and non-insulin-dependent diabetic rats

1991 • 56 citations

Neuropeptide Y release from the paraventricular nucleus increases in association with hyperphagia in streptozotocin-induced diabetic rats

1992 • 56 citations

Peripheral insulin administration attenuates the increase in neuropeptide Y concentrations in the hypothalamic arcuate nucleus of fasted rats

1992 • 52 citations

Metabolic effects of galanin injections into the paraventricular nucleus of the hypothalamus

1992 • 49 citations

Role of galanin in stimulation of pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide

1994 • 49 citations

Blockade of natural and neuropeptide Y-induced carbohydrate feeding by a receptor antagonist PYX-2

1992 • 48 citations

Galanin inhibits insulin and corticosterone release after injection into the PVN

1990 • 47 citations

Neuropeptide Y gene expression in the arcuate nucleus: sexual dimorphism and modulation by testosterone

1993 • 46 citations

Distribution of galanin-immunoreactive cells within sexually dimorphic components of the medial preoptic area of the male and female rat

1993 • 43 citations

Expansion of solidifying saturated fats

1974 • 41 citations

Steroidal regulation of hypothalamic neuropeptide Y release and gene expression

1992 • 41 citations

Increased carbohydrate consumption by rats as a function of 2-deoxy-D-glucose administration

1983 • 41 citations

Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat

1993 • 40 citations

Critical effects of aging and nutritional state on hypothalamic neuropeptide Y and galanin gene expression in lean and genetically obese Zucker rats

1993 • 38 citations

A Possible Direct Action of ACTH on Nerve and Muscle

1973 • 35 citations

Neuropeptide Y attenuates satiety: evidence from a detailed analysis patterns ingestion

1994 • 33 citations

Forskolin and phorbol ester stimulation of neuropeptide Y (NPY) production and secretion by aggregating fetal brain cells in culture: evidence for regulation of NPY biosynthesis at transcriptional and posttranscriptional levels.

1992 • 31 citations

Modulation of hypothalamic galanin gene expression by estrogen in peripubertal rats

1992 • 30 citations

Neuropeptide Y receptor numbers are reduced in the hypothalamus of streptozotocin-diabetic and food-deprived rats: Further evidence of increased activity of hypothalamic NPY-containing pathways

1993 • 30 citations

Neuroendocrine regulation of galanin gene expression

1991 • 29 citations

Neuropeptide Y gene expression in the arcuate nucleus is increased during preovulatory luteinizing hormone surges

1992 • 28 citations

Forebrain and hindbrain involvement of neuropeptide Y in ingestive behaviors of rats

1994 • 27 citations

Dexamethasone-Induced Accumulation of Neuropeptide-Y by Aggregating Fetal Brain Cells in Culture: A Process Dependent on the Developmental Age of the Aggregates*

1991 • 27 citations

Specific hypothalamic neuropeptide Y variation with diet parameters in rats with food choice

1992 • 27 citations

Vasopressin Response to 2-Deoxy-D-Glucose in the Rat*

1980 • 26 citations

Galanin

1991 • 23 citations

Preparation of intercalation compounds between V2O5 gel and bipyridyl metal complexes

1991 • 23 citations

Neuropeptide content in pancreas and pituitary of obese and diabetes mutant mice: Strain and sex differences

1990 • 17 citations

Forskolin and phorbol ester stimulation of neuropeptide Y (NPY) production and secretion by aggregating fetal brain cells in culture: evidence for regulation of NPY biosynthesis at transcriptional and posttranscriptional levels

1992 • 15 citations

On the interations of galanin within the hypothalamic-pituitary axis of the rat

1991 • 15 citations

Hypothalamic galanin in relation to feeding behavior and endocrine systems

1991 • 10 citations

The role of trap-centres on SrTiO3 fine particles during water photolysis

1990 • 7 citations