Specific inhibition of endogenous neuropeptide Y synthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behavior and insulin secretion

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Coated Charcoal Immunoassay of Insulin

1965 • 3,018 citations

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

1982 • 2,244 citations

Isolated removal of hypothalamic or other brain nuclei of the rat

1973 • 1,421 citations

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

1984 • 1,274 citations

Specific regulation of gene expression by antisense, sense and antigene nucleic acids

1990 • 769 citations

Neuroreptide Y: Stimulation of feeding and drinking by injection into the paraventricular nucleus

1984 • 666 citations

Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamus

1985 • 661 citations

Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system—II. Immunohistochemical analysis

1986 • 570 citations

Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides

1993 • 528 citations

An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat

1985 • 523 citations

Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus

1988 • 510 citations

Surgical Disconnection of the Medial Basal Hypothalamus and Pituitary Function in the Rhesus Monkey. I. Gonadotropin Secretion¹,²

1975 • 473 citations

Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion

1985 • 386 citations

Neuropeptide Y-Related Peptides and their Receptors--Are the Receptors Potential Therapeutic Drug Targets?

1993 • 380 citations

Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues

1992 • 379 citations

Structure and expression of the rat neuropeptide Y gene.

1987 • 300 citations

Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effect

1992 • 288 citations

Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat

1987 • 285 citations

The perifornical area: the major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s)

1993 • 250 citations

Reversal of Diabetes Insipidus in Brattleboro Rats: Intrahypothalamic Injection of Vasopressin mRNA

1992 • 237 citations

Neuropeptide Y, epinephrine and norepinephrine in the paraventricular nucleus: Stimulation of feeding and the release of corticosterone, vasopressin and glucose

1988 • 217 citations

Insulin, Glucagon, and Somatostatin Secretion in the Regulation of Metabolism

1978 • 205 citations

Cellular uptake and intracellular fate of antisense oligonucleotides

1992 • 199 citations

Increased Neuropeptide Y Concentrations in Specific Hypothalamic Regions of Streptozocin-Induced Diabetic Rats

1989 • 186 citations

A chronometric approach to the study of feeding behavior

1980 • 181 citations

Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain

1992 • 158 citations

Hypothalamic neuropeptide Y (NPY) in obese Zucker rats: Implications in feeding and sexual behaviors

1990 • 158 citations

Brain neuropeptide Y: An integrator of endocrine, metabolic and behavioral processes

1991 • 148 citations

Repeated hypothalamic stimulation with neuropeptide Y increases daily carbohydrate and fat intake and body weight gain in female rats

1989 • 145 citations

Surgical Disconnection of the Medial Basal Hypothalamus and Pituitary Function in the Rhesus Monkey. II. GH and Cortisol Secretion¹²

1975 • 130 citations

Diurnal rhythm of neuropeptide Y-like immunoreactivity in the suprachiasmatic, arcuate and paraventricular nuclei and other hypothalamic sites

1990 • 130 citations

Neuropeptide Y projection from arcuate nucleus to parvocellular division of paraventricular nucleus: specific relation to the ingestion of carbohydrate

1993 • 126 citations

Diurnal variations in the feeding responses to norepinephrine, neuropeptide Y and galanin in the PVN

1990 • 115 citations

Suppression of neuropeptide Y-elicited eating by adrenalectomy or hypophysectomy: reversal with corticosterone

1989 • 96 citations

Self-selecting albino rats exhibit differential preferences for pure macronutrient diets: Characterization of three subpopulations

1991 • 94 citations

Neuropeptide Y in the arcuate nucleus is modulated by alterations in glucose utilization

1993 • 88 citations

Increased neuropeptide Y concentrations in specific hypothalamic regions of streptozocin-induced diabetic rats

1989 • 78 citations

<b>NEUROPEPTIDE Y AND NOREPINEPHRINE INJECTED INTO THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS ACTIVATE ENDOCRINE </b><b>PANCREAS </b>

1989 • 59 citations

Blockade of natural and neuropeptide Y-induced carbohydrate feeding by a receptor antagonist PYX-2

1992 • 48 citations

NEUROPEPTIDE Y RADIO‐IMMUNOASSAY: CHARACTERIZATION AND APPLICATION

1991 • 23 citations