Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo.

The Role of the Hippocampus in Feedback Regulation of the Hypothalamic-Pituitary-Adrenocortical Axis*

1991 • 1,690 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Apoptosis and Programmed Cell Death in Immunity

1992 • 1,105 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Septic shock: pathogenesis

1991 • 743 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1991 • 675 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor.

1992 • 595 citations

A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.

1989 • 579 citations

Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4

1989 • 372 citations

The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells.

1990 • 347 citations

Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids.

1989 • 339 citations

Clonal expansion precedes anergy and death of V_β8⁺ peripheral T cells responding to staphylococcal enterotoxin B in vivo

1991 • 330 citations

Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic.

1990 • 319 citations

Mifepristone (RU 486) Compared with High-Dose Estrogen and Progestogen for Emergency Postcoital Contraception

1992 • 319 citations

Cytokines as modulators of the hypothalamus-pituitary-adrenal axis

1991 • 289 citations

In vivo biologic and immunohistochemical analysis of interleukin-1 alpha, beta and tumor necrosis factor during experimental endotoxemia. Kinetics, Kupffer cell expression, and glucocorticoid effects.

1991 • 262 citations

Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements.

1992 • 246 citations

Rescue of thymocytes and T cell hybridomas from glucocorticoid‐induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possible in vitro model for positive selection of the T cell repertoire

1991 • 199 citations

INDUCTION OF THERAPEUTIC ABORTION IN EARLY PREGNANCY WITH MIFEPRISTONE IN COMBINATION WITH PROSTAGLANDIN PESSARY

1987 • 197 citations

IL-4 and IL-2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis.

1992 • 165 citations

Characterization of uterine epithelium apoptotic cell death kinetics and regulation by progesterone and RU 486.

1992 • 109 citations

Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone.

1991 • 99 citations

Neuroendocrine regulation of in vivo cytokine production and effects: I. In vivo regulatory networks involving the neuroendocrine system, interleukin-1 and tumor necrosis factor-α

1989 • 83 citations

Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice.

1991 • 81 citations

Septic shock: treatment

1991 • 77 citations

Expansion and clonal deletion of peripheral T cells induced by bacterial superantigen is independent of the interleukin‐2 pathway

1992 • 70 citations

Activation of Polyphosphoinositide Hydrolysis in T Cells by H-2 Alloantigen But Not MLS Determinants

1990 • 59 citations

Physiology and pathology of an immunoendocrine feedback loop

1988 • 53 citations

Cyclosporin A markedly enhances superantigen-induced peripheral T cell deletion and inhibits anergy induction.

1992 • 52 citations

The immune-hypothalamo-pituitary-adrenal axis and autoimmunity

1991 • 45 citations

The glucocorticoid antagonist RU38486 mimics interleukin‐1 in its sensitization to the lethal and interleukin‐6‐inducing properties of tumor necrosis factor

1992 • 32 citations

Differential induction of interferon gamma gene expression after activation of CD4+ T cells by conventional antigen and Mls superantigen.

1991 • 30 citations

In vivo T cell tumor therapy with monoclonal antibody directed to the V beta chain of T cell antigen receptor.

1989 • 24 citations

Duration of antagonizing effect of RU486 on the agonist induction of tyrosine aminotransferase via glucocorticoid receptor

1992 • 7 citations