The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

1988 • 684 citations

Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA

1987 • 547 citations

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.

1987 • 365 citations

Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA

1988 • 363 citations

Novel mechanism for translational control in regulation of ferritin synthesis by iron.

1976 • 324 citations

A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

1987 • 250 citations

Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells.

1987 • 165 citations

Both subunits of rat liver ferritin are regulated at a translational level by iron induction

1986 • 164 citations

Secretion of endogenous and exogenous proteins from polarized MDCK cell monolayers.

1986 • 132 citations

The importance of the 3'-untranslated region in the translational control of ferritin mRNA.

1988 • 84 citations

Influence of altered transcription on the translational control of human ferritin expression.

1987 • 64 citations

Isolation of RNA for dot hybridization by heparin-DNase I treatment of whole cell lysate

1987 • 39 citations