Activation of the Cation Channel Long Transient Receptor Potential Channel 2 (LTRPC2) by Hydrogen Peroxide

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

2001 • 877 citations

LTRPC2 Ca2+-Permeable Channel Activated by Changes in Redox Status Confers Susceptibility to Cell Death

2002 • 794 citations

Formation and Hydrolysis of Cyclic ADP-Ribose Catalyzed by Lymphocyte Antigen CD38

1993 • 735 citations

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors

1992 • 732 citations

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

2001 • 714 citations

The MutT Proteins or “Nudix” Hydrolases, a Family of Versatile, Widely Distributed, “Housecleaning” Enzymes

1996 • 671 citations

Ca ²⁺ -Induced Ca ²⁺ Release in Sea Urchin Egg Homogenates: Modulation by Cyclic ADP-Ribose

1991 • 628 citations

Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents.

1996 • 523 citations

From worm to man: three subfamilies of TRP channels

2000 • 490 citations

Immunocyte Ca ²⁺ Influx System Mediated by LTRPC2

2001 • 434 citations

Cyclic ADP-ribose as an endogenous regulator of the non-skeletal type ryanodine receptor Ca2+ channel

1993 • 365 citations

New functions of a long‐known molecule

2000 • 289 citations

Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP.

1993 • 275 citations

Molecular Cloning of a Novel Putative Ca2+Channel Protein (TRPC7) Highly Expressed in Brain

1998 • 255 citations

Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform

2001 • 226 citations

Two different but converging messenger pathways to intracellular Ca2+ release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphate

2000 • 187 citations

ADP-ribosyl Cyclase and Cyclic ADP-ribose Hydrolase Act as a Redox Sensor

2001 • 132 citations

Inhibition of TRP3 Channels by Lanthanides

2000 • 132 citations

Wide distribution of an enzyme that catalyzes the hydrolysis of cyclic ADP-ribose

1993 • 127 citations

[Ca2+]i Changes and Respiratory Burst in Human Neutrophils and Monocytes Induced by NAP-1/Interleukin-8, NAP-2, and gro/MGSA

1991 • 123 citations

The Type 2 Ryanodine Receptor of Neurosecretory PC12 Cells Is Activated by Cyclic ADP-ribose

1996 • 119 citations

Functional properties of the ryanodine receptor type3 (RyR3) Ca2+ release channel

1998 • 119 citations

Human CD38 is an authentic NAD(P)+ glycohydrolase

1998 • 109 citations

Chemiluminescence in hypoxic brain--the second report: cerebral protective effect of mannitol, vitamin E and glucocorticoid.

1985 • 98 citations

Molecular Events in the Activation of Human Neutrophils for Microbial Killing

1994 • 87 citations

Activation of a novel non‐selective cation channel by alloxan and H₂O₂ in the rat insulin‐secreting cell line CRI‐G1

1997 • 67 citations

Mechanisms of IL-8-induced Ca2+ signaling in human neutrophil granulocytes

1999 • 65 citations

Hydrogen Peroxide‐Induced Phospholipase D Activation in Rat Pheochromocytoma PC12 Cells: Possible Involvement of Ca²⁺‐Dependent Protein Tyrosine Kinase

1997 • 58 citations

Hypoxia Differentially Regulates the Mitogen- and Stress-Activated Protein Kinases

2002 • 41 citations

Ion channels and receptor-mediated Ca2+ influx in neutrophil granulocytes.

1993 • 30 citations