Selective release from cultured mammalian cells of heat‐shock (stress) proteins that resemble glia‐axon transfer proteins

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

FORMATION OF ARROWHEAD COMPLEXES WITH HEAVY MEROMYOSIN IN A VARIETY OF CELL TYPES

1969 • 963 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Immunoglobulin heavy chain binding protein

1983 • 849 citations

The Heat Shock Respons

1985 • 809 citations

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 • 607 citations

Stress protein systems of mammalian cells

1986 • 564 citations

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells.

1984 • 522 citations

Cellular and biochemical events in mammalian cells during and after recovery from physiological stress.

1986 • 513 citations

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

1984 • 456 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment.

1985 • 428 citations

hsp70: Nuclear concentration during environmental stress and cytoplasmic storage during recovery

1984 • 400 citations

Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides

1980 • 395 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Organization of actin in the leading edge of cultured cells: influence of osmium tetroxide and dehydration on the ultrastructure of actin meshworks.

1981 • 340 citations

Common Control of the Heat Shock Gene and Early Adenovirus Genes: Evidence for a Cellular E1A-like Activity

1984 • 331 citations

The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.

1985 • 301 citations

Heat shock-like protein is transferred from glia to axon

1986 • 229 citations

The olfactory marker protein in the olfactory system of the mouse during development

1980 • 220 citations

Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro

1988 • 219 citations

The heat shock response of eukaryotic cells

1984 • 216 citations

Cell-to-cell transfer of glial proteins to the squid giant axon: The glia- neuron protein transfer hypothesis

1977 • 189 citations

Heat Shock Response of Eukaryotic Cells

1985 • 183 citations

Contribution of actin to the structure of the cytoplasmic matrix.

1984 • 172 citations

Intracellular localization of heat shock proteins in Drosophila

1980 • 169 citations

Constitutively Expressed Rat mRNA Encoding a 70-Kilodalton Heat-Shock-Like Protein

1985 • 164 citations

Cellular responses to stress: Comparison of a family of 71–73‐kilodalton proteins rapidly synthesized in rat tissue slices and canavanine‐treated cells in culture

1981 • 162 citations

Selective induction of a heat shock gene in fibre tracts and cerebellar neurons of the rabbit brain detected by in situ hybridization

1987 • 145 citations

Common control of the heat shock gene and early adenovirus genes: evidence for a cellular E1A-like activity.

1984 • 142 citations

Evidence for the glia-neuron protein transfer hypothesis from intracellular perfusion studies of squid giant axons.

1977 • 132 citations

Association between the mammalian 110,000-dalton heat-shock protein and nucleoli.

1983 • 121 citations

Purification and initial characterization of the 71-kilodalton rat heat-shock protein and its cognate as fatty acid binding proteins

1986 • 104 citations

Constitutively expressed rat mRNA encoding a 70-kilodalton heat-shock-like protein.

1985 • 104 citations

The 68,000-dalton neurofilament-associated polypeptide is a component of nonneuronal cells and of skeletal myofibrils

1980 • 77 citations

Selective externalization of an ATP-binding protein structurally related to the clathrin-uncoating ATPase/heat shock protein in vesicles containing terminal transferrin receptors during reticulocyte maturation.

1986 • 72 citations

The relationship of the rat brain 68 kDa microtubule-associated protein with synaptosomal plasma membranes and with the Drosophila 70 kDa heat-shock protein

1984 • 71 citations

The presence of transfer RNA in the axoplasm of the squid giant axon

1977 • 62 citations

Axonal transport of a heat shock protein in the rabbit visual system.

1985 • 57 citations

Glial polypeptides transferred into the squid giant axon

1984 • 56 citations

Macromolecular transfer from glia to the axon.

1981 • 56 citations

Coprecipitation of heat shock proteins with a cell surface glycoprotein.

1982 • 52 citations

A major heat-shock protein defined by a monoclonal antibody.

1984 • 49 citations

Possible cytoskeletal association of 69,000- and 68,000-dalton heat shock proteins and structural relations among heat shock proteins in murine mastocytoma cells.

1986 • 46 citations

Intracellular distribution of mammalian stress proteins. Effects of cytoskeletal-specific agents.

1987 • 45 citations

The 73 kilodalton heat shock cognate protein purified from rat brain contains nonesterified palmitic and stearic acids

1986 • 41 citations

Decreased Expression of the Stress Protein HSP70 Is an Early Event in Murine Erythroleukemic Cell Differentiation

1988 • 39 citations

The Brain 68‐Kilodalton Microtubule‐Associated Protein Is a Cognate Form of the 70‐Kilodalton Mammalian Heat‐Shock Protein and Is Present as a Specific Isoform in Synaptosomal Membranes

1986 • 35 citations

Comparison of labeled heat shock proteins in neuronal and non-neuronal cells of Aplysia californica

1985 • 32 citations

Selective isoactin release from cultured embryonic skeletal muscle cells.

1982 • 32 citations

A retinal heat shock protein is associated with elements of the cytoskeleton and binds to calmodulin

1986 • 31 citations

Possible Cytoskeletal Association of 69,000- and 68,000-Dalton Heat Shock Proteins and Structural Relations among Heat Shock Proteins in Murine Mastocytoma Cells

1986 • 31 citations

The Synthesis and Possible Transport of Specific Proteins by Cells Associated with Brain Capillaries

1980 • 27 citations

Decreased expression of the stress protein HSP70 is an early event in murine erythroleukemic cell differentiation.

1988 • 26 citations

Fine-Structural and Related Aspects of Nonmuscle-Cell Motility

1981 • 24 citations

Stress Responses in Avian and Mammalian Cells

1985 • 18 citations

Characterization of Glial Proteins Transferred into the Squid Giant Axon

1987 • 14 citations

Protein and RNA synthesis in cerebral microvessels: A radioautographic study

1981 • 14 citations

Subcellular particles involved in the translocation of proteins in rat brain

1979 • 13 citations