Proposed structure of putative glucose channel in GLUT1 facilitative glucose transporter

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

Facilitative glucose transporters

1994 • 1,103 citations

Interior and surface of monomeric proteins

1987 • 924 citations

Molecular Biology of Mammalian Glucose Transporters

1990 • 852 citations

Nicotinic Acetylcholine Receptor an 9 Å Resolution

1993 • 822 citations

The glucose transporter family: structure, function and tissue-specific expression

1993 • 773 citations

Reconstitution and Purification of the D-Glucose Transport Protein from Human Erythrocytes

1977 • 652 citations

The role of the α-helix dipole in protein function and structure

1985 • 517 citations

Facilitated diffusion of glucose

1990 • 365 citations

Nature of the charged-group effect on the stability of the C-peptide helix.

1985 • 313 citations

Mammalian passive glucose transporters: members of an ubiquitous family of active and passive transport proteins

1993 • 279 citations

Structural requirements for binding to the sugar-transport system of the human erythrocyte

1973 • 226 citations

Mammalian facilitative glucose transporters: Evidence for similar substrate recognition sites in functionally monomeric proteins

1992 • 198 citations

Glucose transporters serve as water channels.

1990 • 197 citations

Topological distribution of four-alpha-helix bundles.

1989 • 189 citations

Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes.

1992 • 170 citations

Glucose transporter oligomeric structure determines transporter function. Reversible redox-dependent interconversions of tetrameric and dimeric GLUT1.

1992 • 168 citations

Protein folding: Evaluation of some simple rules for the assembly of helices into tertiary structures with myoglobin as an example

1979 • 155 citations

Characterization and Expression of Human HepG2/Erythrocyte Glucose-Transporter Gene

1988 • 148 citations

Four helix bundle diversity in globular proteins

1994 • 143 citations

alpha-Helix dipole model and electrostatic stabilization of 4-alpha-helical proteins.

1982 • 131 citations

Fourier transform infrared spectroscopic study of the structure and conformational changes of the human erythrocyte glucose transporter.

1987 • 130 citations

Topology of the Glut 1 glucose transporter deduced from glycosylation scanning mutagenesis.

1994 • 127 citations

The alpha-helix as an electric macro-dipole.

1976 • 114 citations

Use of site-directed fluorescence labeling to study proximity relationships in the lactose permease of Escherichia coli

1993 • 113 citations

The prediction of transmembrane protein sequences and their conformation: an evaluation

1990 • 113 citations

The pKa values of two histidine residues in human haemoglobin, the Bohr effect, and the dipole moments of α-helices

1985 • 105 citations

Molecular anatomy and molecular design of channel proteins

1990 • 104 citations

Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding.

1994 • 91 citations

Investigation of the structure and function of the human erythrocyte glucose transporter by proteolytic dissection

1987 • 89 citations

Site-directed mutagenesis of GLUT1 in helix 7 residue 282 results in perturbation of exofacial ligand binding.

1992 • 86 citations

The monosaccharide transporter of the human erythrocyte. Transport activity upon reconstitution.

1981 • 79 citations

Prediction and analysis of structure, stability and unfolding of thermolysin-like proteases

1993 • 76 citations

The monosaccharide transport system of the human erythrocyte. Orientation upon reconstitution

1980 • 75 citations

An algorithm to generate low-resolution protein tertiary structures from knowledge of secondary structure.

1994 • 73 citations

The rat facilitated glucose transporter gene. Transformation and serum-stimulated transcription initiate from identical sites.

1988 • 66 citations

Substitution of leucine for tryptophan 412 does not abolish cytochalasin B labeling but markedly decreases the intrinsic activity of GLUT1 glucose transporter.

1991 • 54 citations

Structural basis of human erythrocyte glucose transporter function in reconstituted vesicles.

1986 • 53 citations

Substitution at Pro385 of GLUT1 perturbs the glucose transport function by reducing conformational flexibility.

1994 • 52 citations

Structural basis of human erythrocyte glucose transporter function in proteoliposome vesicles: circular dichroism measurements.

1987 • 50 citations

Structural basis of human erythrocyte glucose transporter function in reconstituted system. Hydrogen exchange.

1986 • 47 citations

Domain assembly of the GLUT1 glucose transporter

1994 • 40 citations

Electrostatic stabilization in four‐helix bundle proteins

1993 • 40 citations

Evidence that facilitative glucose transporters may fold as beta-barrels.

1993 • 35 citations

Conformational Study of a Nine Residue Fragment of the Antigenic Loop of Foot-and-Mouth Disease Virus

1992 • 34 citations

Further characterization and chemical purity assessment of the human erythrocyte glucose transporter preparation

1986 • 29 citations

The glucose transport activity of GLUT1 is markedly decreased by substitution of a single amino acid with a different charge at residue 415

1991 • 25 citations

Functional Consequences of Proline Mutations in the Putative Transmembrane Segments 6 and 10 of the Glucose Transporter GLUT1

1995 • 23 citations

Predicted secondary structure of the 20 S proteasome and model structure of the putative peptide channel

1994 • 18 citations

An assessment of the effect of the helix dipole in protein structures

1994 • 15 citations

A "Cysteineless" GLUT1 Glucose Transporter Has Normal Function When Expressed in Xenopus Oocytes

1995 • 14 citations