The best control for the specificity of RNAi

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Mechanisms of gene silencing by double-stranded RNA

2004 • 2,439 citations

A new logic for DNA engineering using recombination in Escherichia coli

1998 • 1,199 citations

Unlocking the potential of the human genome with RNA interference

2004 • 1,066 citations

Induction of an interferon response by RNAi vectors in mammalian cells

2003 • 972 citations

Recombineering: a powerful new tool for mouse functional genomics

2001 • 743 citations

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)

2003 • 530 citations

Systematic genome-wide screens of gene function

2004 • 305 citations

RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells

2005 • 91 citations

Simplified generation of targeting constructs using ET recombination

1999 • 73 citations

Simplified generation of targetting constructs using ET recombination

1999 • 71 citations

A simple two-step, 'hit and fix' method to generate subtle mutations in BACs using short denatured PCR fragments

2003 • 54 citations