Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock.

APACHE II-A Severity of Disease Classification System

1986 • 12,607 citations

A Controlled Clinical Trial of High-Dose Methylprednisolone in the Treatment of Severe Sepsis and Septic Shock

1987 • 1,434 citations

Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome

1993 • 1,068 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect on mitogen-induced lymphocyte proliferation.

1979 • 567 citations

Corticotropin-Releasing Activity of Monokines

1985 • 500 citations

Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids.

1993 • 457 citations

High circulating levels of interleukin-6 in patients with septic shock: Evolution during sepsis, prognostic value, and interplay with other cytokines

1991 • 446 citations

Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma.

1991 • 170 citations

The adrenal glands.

1991 • 168 citations

Adrenocortical function: An indicator of severity of disease and survival in chronic critically ill patients

1992 • 139 citations

Cortisol receptor resistance: the variability of its clinical presentation and response to treatment.

1992 • 128 citations

Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription.

1991 • 112 citations

Occult Hypoadrenalism in Critically Ill Patients

1993 • 70 citations

Potentiation of glucocorticoid receptor-mediated gene expression by heat and chemical shock.

1994 • 68 citations

A simple cytochemical method for distinguishing EAC rosettes formed by lymphocytes and monocytes

1979 • 41 citations

Corticosteroids in sepsis and septic shock: has the jury reached a verdict?

1989 • 10 citations