Effects of opiate antagonist treatment into either the periaqueductal grey or nucleus accumbens on heroin-induced locomotor activation

Problems of Drug Dependence

1969 • 970 citations

Intracranial self-administration of morphine into the ventral tegmental area in rats

1981 • 497 citations

Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity.

1983 • 355 citations

The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat

1979 • 354 citations

Reinforcing effects of morphine in the nucleus accumbens

1982 • 254 citations

Reinforcing effects of brain microinjections of morphine revealed by conditioned place preference

1982 • 238 citations

Self-administration of methionine enkephalin into the nucleus accumbens

1984 • 238 citations

Neuroanatomical focus for morphine and enkaphalin-induced hypermotility

1977 • 209 citations

Interactions between d-Ala-Met-enkephalin, A10 dopaminergic neurones, and spontaneous behaviour in the rat

1980 • 203 citations

Locomotor activation induced by infusion of endorphins into the ventral tegmental area: evidence for opiate-dopamine interactions.

1980 • 182 citations

Conditioning and place-specific sensitization of increases in activity induced by morphine in the VTA

1984 • 181 citations

Stimulant effects of enkephalin microinjection into the dopaminergic A10 area

1979 • 178 citations

Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat

1985 • 175 citations

The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus

1981 • 137 citations

Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat.

1984 • 117 citations

Quaternary narcotic antagonists' relative ability to prevent antinociception and gastrointestinal transit inhibition in morphine-treated rats as an index of peripheral selectivity

1982 • 89 citations

Blockade of amphetamine but not opiate-induced locomotion following antagonism of dopamine function in the rat

1986 • 81 citations

Low doses of methylnaloxonium in the nucleus accumbens antagonize hyperactivity induced by heroin in the rat

1985 • 78 citations

Neural substrates of opiate reinforcement

1983 • 71 citations

Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists.

1981 • 70 citations