IκB-kinase/nuclear factor-κB signaling prevents thermal injury–induced gut damage by inhibiting c-Jun NH2-terminal kinase activation*

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

NF-κB at the crossroads of life and death

2002 • 2,684 citations

Signal transduction by tumor necrosis factor and its relatives

2001 • 1,623 citations

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

1999 • 978 citations

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

2001 • 772 citations

Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling

2001 • 725 citations

Role of JNK activation in apoptosis: A double-edged sword

2005 • 704 citations

NF-κB Inducers Upregulate cFLIP, a Cycloheximide-Sensitive Inhibitor of Death Receptor Signaling

2001 • 583 citations

The NF-κB Activation Pathway: A Paradigm in Information Transfer from Membrane to Nucleus

1999 • 485 citations

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

2003 • 482 citations

Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets

2002 • 429 citations

The IκB/NF-κB system: a key determinant of mucosal inflammation and protection

2000 • 377 citations

Role of NF-κB in immune and inflammatory responses in the gut

1998 • 335 citations

JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

2004 • 278 citations

Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-κB

2004 • 202 citations

IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium

2004 • 184 citations

NF-κB as an Integrator of Diverse Signaling Pathways: The Heart of Myocardial Signaling?

2003 • 144 citations

Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury

2002 • 105 citations

Blockade of NF- κ B Activation and Donation of Nitric Oxide: New Treatment Options in Inflammatory Bowel Disease?

2002 • 77 citations

Mechanisms of Neutropenia Involving Myeloid Maturation Arrest in Burn Sepsis

1998 • 73 citations

The p38 mitogen‐activated protein kinase regulates interleukin‐1β‐induced IL‐8 expression via an effect on the IL‐8 promoter in intestinal epithelial cells

2003 • 65 citations

Signaling crosstalk between NF-κB and JNK

2004 • 64 citations

Cell proliferation, apoptosis, NF-κB expression, enzyme, protein, and weight changes in livers of burned rats

2001 • 64 citations

Role of TNF-α in gut mucosal changes after severe burn

2002 • 57 citations

Proapoptotic effect of curcumin on human neutrophils: Activation of the p38 mitogen-activated protein kinase pathway*

2005 • 57 citations

CHANGES IN GUT MUCOSAL NITRIC OXIDE SYNTHASE (NOS) ACTIVITY AFTER THERMAL INJURY AND ITS RELATION WITH BARRIER FAILURE

1999 • 56 citations

Role of p38 MAPK in the Regulation of Apoptosis Signaling Induced by TNF-α in Differentiated PC12 Cells

2002 • 48 citations

Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity

2003 • 22 citations

Heat shock inhibition of lipopolysaccharide-mediated tumor necrosis factor expression is associated with nuclear induction of MKP-1 and inhibition of mitogen-activated protein kinase activation

2004 • 19 citations