Covalent chemical events in immune induction: fundamental and therapeutic aspects

The MAPK signaling cascade

1995 • 3,300 citations

Enzyme structure and mechanism

1977 • 2,935 citations

Enzyme structure and mechanism

1978 • 2,897 citations

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

The Th1–Th2 hypothesis of HIV infection: new insights

1994 • 708 citations

Immunobiology of the Macrophage

1976 • 622 citations

Pyridoxal phosphate-dependent enzymes

1995 • 344 citations

Conformation and Function of the N-Linked Glycan in the Adhesion Domain of Human CD2

1995 • 305 citations

Structural Features of Polysaccharides That Induce Intra-Abdominal Abscesses

1993 • 266 citations

Ultraviolet radiation and immunology: something new under the sun--presidential address.

1994 • 261 citations

Conversion of Bacteriorhodopsin into a Chloride Ion Pump

1995 • 239 citations

Vitamin B6 and Immune Competence

2009 • 187 citations

Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function

1995 • 179 citations

Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in disease.

1994 • 174 citations

Therapeutic potentiation of the immune system by costimulatory Schiff-base-forming drugs

1995 • 151 citations

Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5å resolution

1994 • 139 citations

Covalently bound pyrroloquinoline quinone is the organic prosthetic group in human placental lysyl oxidase

1986 • 88 citations

The Requirement for Macrophage-Lymphocyte Interaction in T Lymphocyte Proliferation Induced by Generation of Aldehydes on Cell Membranes

1975 • 83 citations

Polyvalent melanoma cell vaccine induces delayed-type hypersensitivity and in vitro cellular immune response.

1994 • 71 citations

Ligand Binding by the Immunoglobulin Superfamily Recognition Molecule CD2 Is Glycosylation-independent

1995 • 64 citations

Modulation of Immunity by Ultraviolet Radiation: Key Effects on Antigen Presentation

1995 • 57 citations

Galactose Oxidation in the Design of Immunogenic Vaccines

1992 • 53 citations

Evidence for an intercellular covalent reaction essential in antigen-specific T cell activation.

1989 • 52 citations

Structure-function relationships for polysaccharide-induced intra-abdominal abscesses

1994 • 52 citations

Intracellular signaling activity of synthetic (14R)-, (14S)-, and (14RS)-14-hydroxy-4,14-retro-retinol

1994 • 45 citations

An essential role for constitutive Schiff base-forming ligands in antigen presentation to murine T cell clones.

1990 • 43 citations

The pharmacokinetics, tolerability and pharmacodynamics of tucaresol (589C80; 4[2‐formyl‐3‐hydroxyphenoxymethyl] benzoic acid), a potential anti‐sickling agent, following oral administration to healthy subjects.

1993 • 38 citations

Comparative studies on ion pumps of the bacterial rhodopsin family

1994 • 37 citations

Immunotherapy of chronic hepatitis B by anti HBV vaccine

1995 • 36 citations

The primary alloresponse of human CD4⁺ T cells is dependent on B7 (CD80), augmented by CD58, but relatively uninfluenced by CD54 expression

1995 • 33 citations

A decomposition product of a contaminant implicated in L-tryptophan eosinophilia myalgia syndrome affects spinal cord neuronal cell death and survival through stereospecific, maturation and partly interleukin-1-dependent mechanisms.

1993 • 33 citations

HIV-Specific Vaccine Therapy: Concepts, Status, and Future Directions

1992 • 28 citations

Erythrocyte rosettes provide an analogue for Schiff base formation in specific T cell activation.

1990 • 28 citations

Liver damage: mechanisms and management

1994 • 27 citations

Hypoxia and the Rheumatoid Joint: Immunological and Therapeutic Implications

1995 • 23 citations

Functional abolition of monocyte HLA-DR by aldehyde treatment. A novel approach to studies of class II restriction elements in antigen presentation.

1988 • 6 citations