Relationship between Yeast Polyribosomes and Upf Proteins Required for Nonsense mRNA Decay

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1992 • 3,258 citations

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1993 • 660 citations

The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon.

1991 • 487 citations

Premature translational termination triggers mRNA decapping

1994 • 399 citations

Gene products that promote mRNA turnover in Saccharomyces cerevisiae.

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1996 • 328 citations

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1995 • 279 citations

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Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant.

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1987 • 250 citations

Upf1p, Nmd2p, and Upf3p Are Interacting Components of the Yeast Nonsense-Mediated mRNA Decay Pathway

1997 • 229 citations

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1983 • 188 citations

Purification and characterization of the Upf1 protein: a factor involved in translation and mRNA degradation.

1995 • 184 citations

A simple procedure for maximum yield of high-quality plasmid DNA.

1990 • 181 citations

Identification and Characterization of Mutations in the UPF1 Gene That Affect Nonsense Suppression and the Formation of the Upf Protein Complex but Not mRNA Turnover

1996 • 152 citations

Characterization of the XRN1 gene encoding a 5'→3' exoribonuclease: sequence data and analysis of disparate protein and mRNA levels of gene-disrupted yeast cells

1992 • 142 citations

The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm.

1995 • 132 citations

Identification of an additional gene required for eukaryotic nonsense mRNA turnover.

1995 • 113 citations

Improved filter hybridization method for detection of single copy sequences in large eukaryotic genomes

1983 • 48 citations

Rapidc-mycmRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA

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Rapid and simple isolation of DNA from agarose gels

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Correlation between tubulin mRNA stability and poly(A) length over the cell cycle of Physarum polycephalum

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