Substance P responsiveness of smooth muscle cells is regulated by the integrin ligand, thrombospondin.

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

The smooth muscle cell in culture

1979 • 1,546 citations

Multi‐faceted regulation of cell differentiation by extracellular matrix

1993 • 610 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Regulation of differentiated properties and proliferation of arterial smooth muscle cells.

1990 • 556 citations

Arg‐Gly‐Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1

1991 • 543 citations

Developmental mechanisms underlying pathology of arteries

1990 • 445 citations

Synthesis and secretion of thrombospondin by cultured human endothelial cells.

1982 • 311 citations

Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix.

1983 • 266 citations

Light microscopic immunolocation of thrombospondin in human tissues.

1985 • 265 citations

Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin.

1986 • 259 citations

Thrombospondin: synthesis and secretion by cells in culture.

1982 • 259 citations

Cell surface thrombospondin is functionally essential for vascular smooth muscle cell proliferation

1988 • 256 citations

Isolation and characterization of a glycoprotein secreted by aortic endothelial cells in culture. Apparent identity with platelet thrombospondin.

1981 • 216 citations

Effects of Modifications of the RGD Sequence and Its Context on Recognition by the Fibronectin Receptor

1989 • 213 citations

Unique distribution of the extracellular matrix component thrombospondin in the developing mouse embryo.

1988 • 212 citations

Monoclonal Antibodies Which Alter the Morphology of Cultured Chick Myogenic Cells

1982 • 212 citations

The inhibition of DRB (5,6-dichloro-1-β-d-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells

1976 • 204 citations

Platelet thrombospondin mediates attachment and spreading of human melanoma cells.

1987 • 196 citations

Basement Membrane Regulation of Sertoli Cells*

1994 • 191 citations

The G-protein linked receptor facts book

1994 • 181 citations

Identification and characterization of thrombospondin-4, a new member of the thrombospondin gene family.

1993 • 143 citations

Agrin isoforms and their role in synaptogenesis

1992 • 140 citations

Deposition and role of thrombospondin in the histogenesis of the cerebellar cortex.

1990 • 118 citations

Receptors for Extracellular Matrix

1991 • 110 citations

Disulfides modulate RGD-inhibitable cell adhesive activity of thrombospondin.

1992 • 110 citations

Molecular and cellular aspects of basement membranes

1994 • 109 citations

Subcellular fractionation and morphology of calf aortic smooth muscle cells: studies on whole aorta, aortic explants, and subcultures grown under

1977 • 97 citations

The in situ localization of tenascin splice variants and thrombospondin 2 mRNA in the avian embryo

1993 • 87 citations

Receptors for substance P.I. The pharmacological preparations

1984 • 79 citations

A second thrombospondin gene in the mouse is similar in organization to thrombospondin 1 but does not respond to serum.

1991 • 66 citations

Immunohistochemical identification of thrombospondin in normal human brain and in Alzheimer's disease.

1992 • 64 citations

Characterization of the mouse thrombospondin gene and evaluation of the role of the first intron in human gene expression.

1990 • 55 citations

Molecular requirements for the interaction of thrombospondin with thrombin-activated human platelets: modulation of platelet aggregation

1992 • 55 citations

Structure and chromosomal localization of the human thrombospondin gene

1990 • 54 citations

Maintenance of contractility in dissociated smooth muscle: low-density cultures in a defined medium

1993 • 50 citations

Non‐cholinergic neurotransmission and the effects of peptides on the urinary bladder of guinea‐pigs and rabbits.

1986 • 48 citations

Cloning and sequencing of chicken thrombospondin

1991 • 47 citations

Factors affecting the expression of acetylcholine receptors on rat sensory neurones in culture.

1986 • 26 citations

Effects of substance P on the isolated iris sphincter muscle of the albino rabbit.

1982 • 12 citations

Extracellular matrix regulates smooth muscle responses to substance P.

1992 • 12 citations