Immunohistochemical identification of thrombospondin in normal human brain and in Alzheimer's disease.

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1991 • 4,120 citations

A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau

1991 • 1,397 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 • 899 citations

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1981 • 803 citations

Perforant pathway changes and the memory impairment of Alzheimer's disease

1986 • 665 citations

The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

1986 • 575 citations

Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.

1990 • 407 citations

Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: I. Superior frontal and inferior temporal cortex

1990 • 367 citations

Thrombospondin modulates focal adhesions in endothelial cells.

1989 • 271 citations

Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age

1985 • 238 citations

Vitronectin and thrombospondin promote retinal neurite outgrowth: Developmental regulation and role of integrins

1991 • 237 citations

Unique distribution of the extracellular matrix component thrombospondin in the developing mouse embryo.

1988 • 212 citations

Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains.

1987 • 206 citations

Platelet thrombospondin mediates attachment and spreading of human melanoma cells.

1987 • 196 citations

Physiology of Thrombospondin

1990 • 195 citations

Altered angioarchitecture in selected areas of brains with Alzheimer's disease

1990 • 176 citations

Thrombospondins

1991 • 169 citations

Binding and degradation of platelet thrombospondin by cultured fibroblasts.

1984 • 126 citations

Pathological proteins Tau 64 and 69 are specifically expressed in the somatodendritic domain of the degenerating cortical neurons during Alzheimer's disease

1990 • 122 citations

Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.

1992 • 118 citations

Deposition and role of thrombospondin in the histogenesis of the cerebellar cortex.

1990 • 118 citations

Thrombospondin and a 140 kd fragment promote adhesion and neurite outgrowth from embryonic central and peripheral neurons and from PC12 cells

1991 • 114 citations

Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. Characterization and mapping of their epitopes.

1986 • 111 citations

Human brain glial cells synthesize thrombospondin.

1986 • 110 citations

Association between vascular basement membrane components and the lesions of Alzheimer's disease

1991 • 107 citations

Interactions of thrombospondin with sulfated glycolipids and proteoglycans of human melanoma cells.

1988 • 68 citations

A second thrombospondin gene in the mouse is similar in organization to thrombospondin 1 but does not respond to serum.

1991 • 66 citations

Studies of the Receptors on Melanoma Cells for Plasmodium Falciparum Infected Erythrocytes

1989 • 30 citations