5‐Methoxy‐N,N‐dimethyltryptamine‐induced analgesia is blocked by α‐adrenoceptor antagonists in rats

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

Chronic catheterization of the spinal subarachnoid space

1976 • 2,244 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. IV. DISTRIBUTION OF MONOAMINE NERVE TERMINALS IN THE CENTRAL NERVOUS SYSTEM.

1965 • 1,543 citations

Presynaptic regulation of catecholamine release

1974 • 1,145 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. II. EXPERIMENTALLY INDUCED CHANGES IN THE INTRANEURONAL AMINE LEVELS OF BULBOSPINAL NEURON SYSTEMS.

1965 • 1,004 citations

SIXTH GADDUM MEMORIAL LECTURE NATIONAL INSTITUTE FOR MEDICAL RESEARCH, MILL HILL, JANUARY 1977

1977 • 935 citations

Brainstem Control of Spinal Pain-Transmission Neurons

1978 • 820 citations

A functional basis for classification of α-adrenergic receptors

1977 • 802 citations

PRESYNAPTIC RECEPTORS AND THEIR ROLE IN THE REGULATION OF TRANSMITTER RELEASE.

1977 • 616 citations

Preferential blockade of presynaptic α-adrenoceptors by yohimbine

1975 • 466 citations

Yohimbine: a pharmacological probe for study of the alpha 2-adrenoreceptor.

1983 • 435 citations

Binding characteristics of 3H-prazosin to rat brain α-adrenergic receptors

1979 • 419 citations

Multiple apparent alpha-noradrenergic receptor binding sites in rat brain: effect of 6-hydroxydopamine.

1979 • 362 citations

The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurones in the cat

1978 • 334 citations

Selective reduction by noradrenaline and 5-hydroxytryptamine of nociceptive responses of cat dorsal horn neurones

1978 • 332 citations

Spinal noradrenergic terminal system mediates antinociception

1980 • 317 citations

Reversal of morphine and stimulus-produced analgesia by subtotal spinal cord lesions

1977 • 303 citations

Opiate and stimulus-produced analgesia: functional anatomy of a medullospinal pathway.

1976 • 289 citations

Alpha-adrenergic receptor subtypes: Quantitative assessment by ligand binding

1979 • 264 citations

The inhibitory action of noradrenaline and other monoamines on spinal neurones

1966 • 262 citations

Multiple apparent alpha-noradrenergic receptor binding sites in rat brain: effect of 6-hydroxydopamine.

1979 • 199 citations

A new projection from locus coeruleus to the spinal ventral columns: histochemical and biochemical evidence

1978 • 176 citations

Noradrenaline regulation of pain-transmission in the spinal cord mediated by α-adrenoceptors

1979 • 158 citations

Effect of intrathecally administered noradrenergic antagonists on nociception in the rat

1984 • 134 citations

Effects of 5-hydroxytryptamine and bradykinin in cat dorsal horn neurones activated by noxious stimuli

1976 • 124 citations

Changes in sensitivity to intrathecal norepinephrine and serotonin after 6-hydroxydopamine (6-OHDA), 5,6-dihydroxytryptamine (5,6-DHT) or repeated monoamine administration.

1982 • 108 citations

Hallucinogenic drugs of the indolealkylamine type and central monoamine neurons.

1971 • 101 citations

Noradrenergic-serotonergic interactions and nociception in the rat

1986 • 100 citations

Functional aspects of bulbospinal monoaminergic projections in modulating processing of somatosensory information.

1981 • 85 citations

FURTHER STUDIES ON THE MODE OF ACTION OF PSYCHOTOMIMETIC DRUGS: ANTAGONISM OF THE EXCITATORY ACTIONS OF 5‐HYDROXYTRYPTAMINE BY METHYLATED DERIVATIVES OF TRYPTAMINE

1974 • 55 citations

Yohimbine and rauwolscine inhibit 5-hydroxytryptamine-induced contraction of large coronary arteries of calf through blockade of 5 HT2 receptors

1983 • 53 citations

Determination of subtype selectivity of alpha-adrenergic antagonists: comparison of selective and nonselective radioligands.

1981 • 40 citations

Analgesia induced by 5-hydroxytryptamine receptor agonists is blocked or reversed by noradrenaline-depletion in rats

1986 • 37 citations

Blockade and reversal of 5-Methoxy-N, N-Dimethyltryptamine-induced analgesia following noradrenaline depletion

1985 • 37 citations

Nociception is enhanced after low doses and reduced after high doses of the serotonin receptor agonist 5-methoxy-N,N-dimethyltryptamine

1980 • 33 citations

Blockade of intrathecal 5-hydroxytryptamine-induced antinociception in rats by noradrenaline depletion

1985 • 31 citations

Potentiation of two sympathetic reflexes by yohimbine hydrochloride

1979 • 21 citations

Complete Blockade and Attenuation of 5–Hydroxytryptamine Induced Analgesia Following NA Depletion in Rats and Mice

1985 • 14 citations

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