Models of DNA structure achieve almost perfect discrimination between normal prostate, benign prostatic hyperplasia (BPH), and adenocarcinoma and have a high potential for predicting BPH and prostate cancer

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

1992 • 1,830 citations

DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems

1991 • 1,555 citations

Toxic DNA Damage by Hydrogen Peroxide Through the Fenton Reaction in Vivo and in Vitro

1988 • 1,505 citations

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

1987 • 778 citations

In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides

1995 • 656 citations

Oxidants and antioxidants: State of the art

1991 • 623 citations

Reactive oxygen species in tumorigenesis.

1994 • 479 citations

Genomic Instability Induced by Ionizing Radiation

1996 • 478 citations

Applications of Infrared, Raman, and Resonance Raman Spectroscopy in Biochemistry

1983 • 419 citations

Application of Infrared Spectroscopy to Structure Studies of Nucleic Acids

1970 • 274 citations

Major alterations in the nucleotide structure of DNA in cancer of the female breast.

1991 • 271 citations

Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis

1996 • 229 citations

Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage.

1996 • 219 citations

The etiology of breast cancer characteristic alterations in hydroxyl radical-induced dna base lesions during oncogenesis with potential for evaluating incidence risk

1993 • 197 citations

Radiation and hydrogen peroxide induced free radical damage to DNA.

1987 • 169 citations

Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones

1995 • 131 citations

8-Hydroxyadenine (7, 8-dihydro-8-Oxoadenine) induces misincorporation inin vitroDNA synthesis and mutations in NIH 3T3 cells

1995 • 130 citations

Torsion of the testis: a new risk factor for testicular cancer

1987 • 106 citations

The etiology and prediction of breast cancer. Fourier transform-infrared spectroscopy reveals progressive alterations in breast DNA leading to a cancer-like phenotype in a high proportion of normal women

1995 • 97 citations

DNA base modifications and antioxidant enzyme activities in human benign prostatic hyperplasia

1995 • 73 citations

Identification of hydroxyl radical‐induced lesions in DNA base structure: Biomarkers with a putative link to cancer development

1993 • 65 citations

Application of Infrared Raman and Resonance Raman Spectroscopy in Biochemistry

1984 • 62 citations

INFRARED AND RAMAN SPECTROSCOPY

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Molecular biology of prostate cancer progression.

1995 • 50 citations

Possible Mechanism of Induction of Benign Prostatic Hyperplasia by Estradiol and Dihydrotestosterone in Dogs

1996 • 36 citations

Tumor progression to the metastatic state involves structural modifications in DNA markedly different from those associated with primary tumor formation

1996 • 29 citations

Mutagenic DNA base modifications are correlated with lesions in nonneoplastic hepatic tissue of the English sole carcinogenesis model.

1996 • 27 citations