Reactive Oxygen Species Are Involved in Arsenic Trioxide Inhibition of Pyruvate Dehydrogenase Activity

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

1973 • 2,608 citations

Oxidative damage and mitochondrial decay in aging.

1994 • 2,024 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

A Stable Nonfluorescent Derivative of Resorufin for the Fluorometric Determination of Trace Hydrogen Peroxide: Applications in Detecting the Activity of Phagocyte NADPH Oxidase and Other Oxidases

1997 • 1,338 citations

Oxidative Stress in Neurodegenerative Diseases

1996 • 1,336 citations

Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water

1992 • 766 citations

Increased Prevalence of Hypertension and Long-term Arsenic Exposure

1995 • 449 citations

Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms.

1990 • 434 citations

Mutagenicity of arsenic in mammalian cells: Role of reactive oxygen species

1998 • 423 citations

Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae

2000 • 420 citations

The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase.

1996 • 419 citations

Ingested Inorganic Arsenic and Prevalence of Diabetes Mellitus

1994 • 354 citations

Oxidative Stress Promotes Specific Protein Damage inSaccharomyces cerevisiae

2000 • 321 citations

NADH Oxidase Activation Is Involved in Arsenite-Induced Oxidative DNA Damage in Human Vascular Smooth Muscle Cells

2000 • 316 citations

Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite

1999 • 263 citations

Arsenite induces apoptosis in chinese hamster ovary cells by generation of reactive oxygen species

1996 • 241 citations

Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia

2000 • 182 citations

DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells

2000 • 178 citations

Blackfoot Disease in Taiwan: A 30-Year Follow-up Study

1989 • 140 citations

Glutathione peroxidase and catalase modulate the genotoxicity of arsenite

1997 • 132 citations

Arsenite Stimulates Poly(ADP-Ribosylation) by Generation of Nitric Oxide

1998 • 123 citations

Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells

2001 • 119 citations

DMSA, DMPS, and DMPA?as arsenic antidotes*1

1984 • 114 citations

Regulation of Cellular Thiols in Human Lymphocytes by α-Lipoic Acid: A Flow Cytometric Analysis

1997 • 111 citations

Thiol-mediated redox regulation of neutrophil apoptosis

1996 • 104 citations

Complete and Reversible Inhibition of NADPH Oxidase in Human Neutrophils by Phenylarsine Oxide at a Step Distal to Membrane Translocation of the Enzyme Subunits

1995 • 91 citations

General Method to Identify and Enrich Vicinal Thiol Proteins Present in Intact Cells in the Oxidized, Disulfide State

1997 • 81 citations

Calcium-dependent nitric oxide production is involved in arsenite-induced micronuclei

1998 • 81 citations

Reactive Oxygen Species-Mediated Inactivation of Pyruvate Dehydrogenase

1996 • 76 citations

Nitric oxide is involved in arsenite inhibition of pyrimidine dimer excision

2001 • 71 citations

Dithiothreitol Enhances Arsenic Trioxide-Induced Apoptosis in NB4 Cells

1999 • 61 citations

Inhibition of pyruvate dehydrogenase multienzyme complex from Escherichia coli with a bifunctional arsenoxide: selective inactivation of lipoamide dehydrogenase

1981 • 30 citations

Effects of alpha-ketoisovalerate on bovine heart pyruvate dehydrogenase complex and pyruvate dehydrogenase kinase.

1986 • 22 citations