Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

2000 • 2,090 citations

Induction of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells

2000 • 1,577 citations

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

1α,25-Dihydroxyvitamin D3 Inhibits Differentiation, Maturation, Activation, and Survival of Dendritic Cells Leading to Impaired Alloreactive T Cell Activation

2000 • 1,253 citations

In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

2002 • 1,163 citations

1α,25-Dihydroxyvitamin D3 Has a Direct Effect on Naive CD4+ T Cells to Enhance the Development of Th2 Cells

2001 • 1,091 citations

1,25-Dihydroxyvitamin D ₃ Receptors in Human Leukocytes

1983 • 1,030 citations

The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD

1997 • 685 citations

Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.

1998 • 657 citations

Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance

2001 • 627 citations

Vitamin D3 Affects Differentiation, Maturation, and Function of Human Monocyte-Derived Dendritic Cells

2000 • 612 citations

The NOD mouse model of type 1 diabetes: As good as it gets?

1999 • 592 citations

Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions.

1995 • 508 citations

A 1α,25-Dihydroxyvitamin D3 Analog Enhances Regulatory T-Cells and Arrests Autoimmune Diabetes in NOD Mice

2002 • 480 citations

The coming of age of 1,25-dihydroxyvitamin D3 analogs as immunomodulatory agents

2002 • 469 citations

Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3

1994 • 431 citations

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice.

1995 • 428 citations

Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study

1992 • 414 citations

Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus

1999 • 403 citations

Transcriptional Repression of the Interleukin-2 Gene by Vitamin D₃: Direct Inhibition of NFATp/AP-1 Complex Formation by a Nuclear Hormone Receptor

1995 • 399 citations

Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF)

1996 • 362 citations

Vitamin D3: a transcriptional modulator of the interferon-γ gene

1998 • 274 citations

Potent Inhibition of Dendritic Cell Differentiation and Maturation by Vitamin D Analogs

2000 • 271 citations

Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D3

2000 • 240 citations

Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans.

2000 • 238 citations

1-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes

2001 • 231 citations

1,25-Dihydroxyvitamin D3 Prevents Insulitis in NOD Mice

1992 • 230 citations

1,25-Dihydroxyvitamin D3 inhibits dendritic cell differentiation and maturation in vitro

2000 • 222 citations

Mycophenolate Mofetil Impairs the Maturation and Function of Murine Dendritic Cells

2000 • 185 citations

Nuclear factor of activated T cells (NFAT) as a molecular target for 1alpha,25-dihydroxyvitamin D3-mediated effects.

1998 • 180 citations

Cell Death Mediators in Autoimmune Diabetes—No Shortage of Suspects

1997 • 177 citations

Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population

2000 • 162 citations

Nuclear Factor of Activated T Cells (NFAT) as a Molecular Target for 1α,25-Dihydroxyvitamin D3-Mediated Effects

1998 • 139 citations

PREVENTION OF AUTOIMMUNE DESTRUCTION OF SYNGENEIC ISLET GRAFTS IN SPONTANEOUSLY DIABETIC NONOBESE DIABETIC MICE BY A COMBINATION OF AVITAMIN D3 ANALOG AND CYCLOSPORINE1

1998 • 106 citations

Breaking self-tolerance in nonobese diabetic mice.

1996 • 88 citations

Ligands for the vitamin D endocrine system: different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein

2001 • 77 citations

Highly active analogs of 1α,25-dihydroxyvitamin D3 that resist metabolism through C-24 oxidation and C-3 epimerization pathways

2001 • 55 citations

Sex difference in resistance to dexamethasone-induced apoptosis in NOD mice: treatment with 1,25(OH)2D3 restores defect.

1998 • 50 citations