Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats.

Molecular mimicry and autoimmune disease

1987 • 943 citations

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

1985 • 935 citations

Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2.

1986 • 534 citations

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

1985 • 466 citations

Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli

1987 • 449 citations

Lines of T Lymphocytes Induce or Vaccinate Against Autoimmune Arthritis

1983 • 418 citations

Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4.

1985 • 372 citations

Reversal of Experimental Allergic Encephalomyelitis with Monoclonal Antibody to a T-Cell Subset Marker

1985 • 328 citations

Autoantibodies to HLA B27 in the sera of HLA B27 patients with ankylosing spondylitis and Reiter's syndrome. Molecular mimicry with Klebsiella pneumoniae as potential mechanism of autoimmune disease.

1987 • 317 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells.

1985 • 288 citations

The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.

1987 • 226 citations

Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice.

1985 • 194 citations

Rheumatoid Arthritis: Evolving Concepts of Pathogenesis and Treatment

1984 • 152 citations

Anti-interleukin 2 receptor antibody suppresses murine diabetic insulitis and lupus nephritis.

1988 • 141 citations

Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli.

1988 • 133 citations

Passive Transfer of Adjuvant Arthritis in Rats with Living Lymphoid Cells of Sensitized Donors

1963 • 129 citations

The cellular basis of adjuvant arthritis

1983 • 128 citations

Recombinant interferon-gamma induces interleukin 2 receptors on human peripheral blood monocytes.

1986 • 126 citations

Therapy with monoclonal antibody to interleukin 2 receptor spares suppressor T cells and prevents or reverses acute allograft rejection in rats.

1986 • 126 citations

SUPPRESSION OF ADJUVANT DISEASE IN THE RAT BY HETEROLOGOUS ANTILYMPHOCYTE GLOBULIN

1968 • 109 citations

IL-2 rapidly induces natural killer cell adhesion to human endothelial cells. A potential mechanism for endothelial injury.

1988 • 103 citations

The cellular basis of adjuvant arthritis

1983 • 91 citations

Inhibition by cyclosporin A of streptococcal cell wall‐induced arthritis and hepatic granulomas in rats

1986 • 88 citations

Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.

1988 • 78 citations

In vivo treatment with W3/13 (anti-pan T) but not with OX8 (anti-suppressor/cytotoxic T) monoclonal antibodies impedes the development of adjuvant arthritis in rats.

1985 • 73 citations

Immunosuppression of collagen-induced arthritis in mice with an anti-IL-2 receptor antibody.

1988 • 70 citations

Studies on adjuvant‐induced polyarthritis in rats. II. Histogenesis of joint and visceral lesions

1963 • 63 citations

New model of a synthetic adjuvant, N-acetylmuramyl-L-alanyl-D-isoglutamine- induced arthritis: clinical and histologic studies in athymic nude and euthymic rats.

1982 • 60 citations

Molecular, cellular, and functional properties of bone marrow T lymphocyte progenitor clones.

1987 • 50 citations

Infections in the Rheumatic Diseases

1989 • 49 citations

Monoclonal anti-IL-2 receptor antibody in primate renal transplantation.

1987 • 36 citations

Prolongation of rat pancreatic islet allograft survival by treatment of recipient rats with monoclonal anti-interleukin-2 receptor antibody and cyclosporin

1987 • 27 citations

Blocking of interleukin 2 (IL 2) binding to the IL 2 receptor is not required for the in vivo action of anti‐IL 2 receptor monoclonal antibody (mAb). I. The production, characterization and in vivo properties of a new mouse anti‐rat IL 2 receptor mAb that reacts with an epitope different to the one that binds to IL 2 and the mAb ART‐18

1987 • 21 citations

The beta subunit of the interleukin-2 receptor mediates interleukin-2 induction of anti-CD3 redirected cytotoxic capability in large granular lymphocytes

1988 • 17 citations

Anti-interleukin 2 receptor monoclonal antibodies spare phenotypically distinct T suppressor cells in vivo and exert synergistic biological effects.

1988 • 16 citations

Functional blocking of the interleukin-2 receptor (IL-2R) may be important in the efficacy of IL-2R antibody therapy.

1987 • 11 citations

Strip-comb dot immunobinding: a rapid, easy and sensitive method to screen monoclonal antibodies.

1988 • 8 citations