Oxidation of low-density lipoprotein by copper and iron in phosphate buffer

Beyond Cholesterol

1989 • 6,533 citations

Practical Methods for Plasma Lipoprotein Analysis1 1Work supported in part by the U.S. Atomic Energy Commission and by grants (HE06222 and FR00102) from the U.S. Public Health Service.

1968 • 1,255 citations

Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site.

1984 • 849 citations

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

1990 • 627 citations

Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

1983 • 623 citations

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

1984 • 547 citations

Lipoprotein oxidation and lipoprotein-induced cytotoxicity.

1983 • 545 citations

Biochemical structural and functional properties of oxidized low-density lipoprotein

1990 • 536 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells.

1986 • 516 citations

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

1990 • 478 citations

Enhanced macrophage degradation of biologically modified low density lipoprotein.

1983 • 469 citations

Modification of human serum low density lipoprotein by oxidation — Characterization and pathophysiological implications

1987 • 400 citations

Superoxide initiates oxidation of low density lipoprotein by human monocytes.

1987 • 273 citations

Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.

1989 • 250 citations

Role of superoxide in endothelial-cell modification of low-density lipoproteins

1988 • 228 citations

The action of defined oxygen-centred free radicals on human low-density lipoprotein

1989 • 167 citations

Oxidation of lipoprotein Lp(a). A comparison with low-density lipoproteins

1991 • 137 citations

Toxicity of oxidized low‐density lipoprotein to cultured fibroblasts is selective for S phase of the cell cycle

1987 • 112 citations

Implications for in vitro studies of the autoxidation of ferrous ion and the iron-catalyzed autoxidation of dithiothreitol

1982 • 87 citations

Probucol prevents oxidative injury to endothelial cells.

1991 • 85 citations

Lipid peroxide and transition metals are required for the toxicity of oxidized low density lipoprotein to cultured endothelial cells

1991 • 83 citations

Protective role of intracellular glutathione against oxidized low density lipoprotein in cultured endothelial cells

1989 • 80 citations

Sensitivity of tryptophan and related compounds to oxidation induced by lipid autoperoxidation. Application to human serum low- and high-density lipoproteins

1990 • 63 citations

Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity

1987 • 9 citations