Human cartilage glycoprotein‐39 as a candidate autoantigen in rheumatoid arthritis

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

THERAPEUTIC CRITERIA IN RHEUMATOID ARTHRITIS

1949 • 2,904 citations

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Rheumatoid Arthritis

1990 • 1,565 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

Immunisation against heterologous type II collagen induces arthritis in mice

1980 • 1,025 citations

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1990 • 906 citations

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

1993 • 900 citations

Dominance and Crypticity of T Cell Antigenic Determinants

1993 • 838 citations

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family.

1993 • 641 citations

The small heat-shock protein αB-crystallin as candidate autoantigen in multiple sclerosis

1995 • 393 citations

Divergent T-cell cytokine patterns in inflammatory arthritis.

1994 • 388 citations

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

1993 • 383 citations

Proteoglycan‐induced arthritis in balb/c mice

1987 • 298 citations

Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.

1991 • 297 citations

Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

1993 • 280 citations

A NEW BIOCHEMICAL MARKER FOR JOINT INJURY. ANALYSIS OF YKL-40 IN SERUM AND SYNOVIAL FLUID

1993 • 227 citations

Description of the Reference Panel of B-Lymphoblastoid Cell Lines for Factors of the HLA System: The B-Cell Line Panel Designed for the Tenth International Histocompatibility Workshop

1989 • 187 citations

T Cells Cloned from Human Rheumatoid Synovial Membrane Functionally Represent the Th 1 Subset

1992 • 177 citations

HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.

1993 • 154 citations

Immunologically ignorant autoreactive T cells, epitope spreading and repertoire limitation

1995 • 147 citations

Total condylar knee replacement in patients who have rheumatoid arthritis. A ten-year follow-up study.

1990 • 142 citations

Rheumatoid Inflammatory T‐Cell Clones express mostly Th1 but also Th2 and Mixed (Th0‐Like) Cytokine Patterns

1993 • 132 citations

Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period

1990 • 120 citations

Hla‐dr alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis

1990 • 103 citations

T cell receptors in rheumatoid arthritis

1995 • 96 citations

Cellular immune response toward human articular chondrocytes. T cell reactivities against chondrocyte and fibroblast membranes in destructive joint diseases

1990 • 67 citations

Direct binding of autoimmune disease related T cell epitopes to purified Lewis rat MHC class II molecules

1994 • 61 citations

Rapid and sensitive mRNA phenotyping for interleukins (IL-1 to IL-6) and colony-stimulating factors (G-CSF, M-CSF, and GM-CSF) by reverse transcription and subsequent polymerase chain reaction.

1991 • 45 citations

Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases

1990 • 25 citations

Cellular immune responses to cartilage components in rheumatoid arthritis and osteoarthritis: a review and report of a study.

1988 • 19 citations

Novel methods to rapidly and sensitively analyze antigenic peptide binding to MHC class II molecules

1991 • 18 citations

Human cartilage aggrecan CS1 region contains cryptic T-cell recognition sites.

1993 • 15 citations