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Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma

Data up to Jan 2025

Published2011
Citations1,038
References39

Total Citations Per Year

Abstract

References (39)

A Class of $K$-Sample Tests for Comparing the Cumulative Incidence of a Competing Risk

1988 • 4,727 citations

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

2002 • 2,781 citations

Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.

1993 • 2,242 citations

Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

2010 • 1,625 citations

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

2008 • 1,144 citations

Infusion of Cytotoxic T Cells for the Prevention and Treatment of Epstein-Barr Virus–Induced Lymphoma in Allogeneic Transplant Recipients

1998 • 1,103 citations

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

2002 • 912 citations

Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

2008 • 792 citations

A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

2005 • 456 citations

The promise and potential pitfalls of chimeric antigen receptors

2009 • 446 citations

Ganglioside GD2 specific monoclonal antibody 3F8: a phase I study in patients with neuroblastoma and malignant melanoma.

1987 • 404 citations

Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment.

1994 • 391 citations

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

2010 • 342 citations

Immune responses to transgene and retroviral vector in patients treated with ex vivo–engineered T cells

2010 • 341 citations

Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor

2008 • 315 citations

Improving T Cell Therapy for Cancer

2006 • 248 citations

Epstein Barr virus–specific cytotoxic T lymphocytes expressing the anti-CD30ζ artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

2007 • 230 citations

A phase I study of human/mouse chimeric antiganglioside GD2 antibody ch14.18 in patients with neuroblastoma

1995 • 211 citations

Phase II Trial of the Anti-GD2Monoclonal Antibody 3F8 and Granulocyte-Macrophage Colony-Stimulating Factor for Neuroblastoma

2001 • 202 citations

Epstein-Barr virus–specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy

2002 • 197 citations

Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression

2009 • 193 citations

Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors

2002 • 186 citations

Phase I Study of Chimeric Human/Murine Anti–Ganglioside GD2Monoclonal Antibody (ch14.18) With Granulocyte-Macrophage Colony-Stimulating Factor in Children With Neuroblastoma Immediately After Hematopoietic Stem-Cell Transplantation: A Children’s Cancer Group Study

2000 • 179 citations

A Phase I Clinical Trial of the hu14.18-IL2 (EMD 273063) as a Treatment for Children with Refractory or Recurrent Neuroblastoma and Melanoma: a Study of the Children's Oncology Group

2006 • 173 citations

Regression of Experimental Medulloblastoma following Transfer of HER2-Specific T Cells

2007 • 173 citations

Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

2010 • 156 citations

Engraftment of human central memory-derived effector CD8+ T cells in immunodeficient mice

2010 • 154 citations

A Phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma

1997 • 154 citations

A phase I study of neuroblastoma with the anti-ganglioside GD2 antibody 14.G2a

1992 • 151 citations

Consolidation Treatment With Chimeric Anti-GD2-Antibody ch14.18 in Children Older Than 1 Year With Metastatic Neuroblastoma

2004 • 139 citations

Anti-GD2 with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia

2010 • 128 citations

Long-Lived Antitumor CD8+ Lymphocytes for Adoptive Therapy Generated Using an Artificial Antigen-Presenting Cell

2007 • 127 citations

Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy

2011 • 124 citations

Phase I trial of murine monoclonal antibody 14G2a administered by prolonged intravenous infusion in patients with neuroectodermal tumors.

1994 • 117 citations

Expression of MHC class I, MHC class II, and cancer germline antigens in neuroblastoma

2004 • 98 citations

Mechanisms of immune evasion of human neuroblastoma

2005 • 81 citations

Immunogenicity of Human Neuroblastoma

2004 • 53 citations

Target Antigen Expression on a Professional Antigen-Presenting Cell Induces Superior Proliferative Antitumor T-Cell Responses via Chimeric T-Cell Receptors

2005 • 28 citations

Cellular Immunotherapy for Neuroblastoma: A Review of Current Vaccine and Adoptive T Cell Therapeutics

2009 • 13 citations

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