Rationale for active vitamin D analog therapy in senile osteoporosis

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Vitamin D₃and Calcium to Prevent Hip Fractures in Elderly Women

1992 • 2,963 citations

Prediction of bone density from vitamin D receptor alleles

1994 • 1,931 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis

1996 • 997 citations

Intestinal Calcium Absorption and Serum Vitamin D Metabolites in Normal Subjects and Osteoporotic Patients

1979 • 865 citations

Target Cells for 1,25-Dihydroxyvitamin D ₃ in Intestinal Tract, Stomach, Kidney, Skin, Pituitary, and Parathyroid

1979 • 713 citations

1,25(OH) ₂ ‐Vitamin D ₃ receptors: gene regulation and genetic circuitry

1988 • 455 citations

Calcium absorption in women: Relationships to Calcium intake, Estrogen status, and age

1989 • 375 citations

Deficient Production of 1,25-Dihydroxyvitamin D in Elderly Osteoporotic Patients

1981 • 373 citations

Vitamin D status and sex hormone binding globulin: Determinants of bone turnover and bone mineral density in elderly women

1995 • 292 citations

Target cell metabolism of 1,25-dihydroxyvitamin D3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation

1989 • 246 citations

Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women.

1992 • 239 citations

Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3.

1981 • 233 citations

Decrease in serum immunoreactive parathyroid hormone in rats and in parathyroid hormone secretion in vitro by 1,25-dihydroxycholecalciferol.

1975 • 219 citations

Interrelationship among vitamin D metabolism, true calcium absorption, parathyroid function, and age in women: Evidence of an age-related intestinal resistance to 1,25-dihydroxyvitamin D action

1991 • 202 citations

1,25-dihydroxyvitamin D3 inhibits cytokine production by human blood monocytes at the post-transcriptional level

1992 • 194 citations

The influence of age on the intestinal absorption of 47-Ca absorption in post-menopausal osteoporosis.

1965 • 193 citations

Histomorphometric profile and vitamin d status in patients with femoral neck fracture

1982 • 185 citations

The influence of age on bone mineral regulating hormones

1986 • 156 citations

1,25-Dihydroxyvitamin D3 Differentially Regulates the Production of Insulin-Like Growth Factor I (IGF-I) and IGF-Binding Protein-4 in Mouse Osteoblasts*

1991 • 132 citations

Parathyroid Hormone Down-Regulates 1,25-Dihydroxyvitamin D Receptors (VDR) and VDR Messenger Ribonucleic Acidin Vitroand Blocks Homologous Up-Regulation of VDRin Vivo

1990 • 126 citations

Decreased bone formation, mineralization, and enhanced resorption in calcium-deficient rats

1973 • 121 citations

Assessment of biochemical markers of bone metabolism in relation to the occurrence of fracture: A retrospective and prospective population-based study of women

1995 • 114 citations

Markers of bone remodeling in the elderly subject: Effects of vitamin D insufficiency and its correction

1995 • 109 citations

Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction.

1991 • 105 citations

Serum intact parathyroid hormone in a random population sample of men and women: Relationship to anthropometry, life-style factors, blood pressure, and vitamin D

1995 • 96 citations

The 24/25-kDa serum insulin-like growth factor-binding protein is increased in elderly women with hip and spine fractures.

1992 • 82 citations

Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women.

1995 • 82 citations

Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3.

1994 • 73 citations

Vitamin D Deficiency in Welfare Institutions for the Aged

1980 • 64 citations

Studies on regulation of insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-4 production in human bone cells

1992 • 59 citations

Nontranscriptional effects of steroid hormones.

1993 • 55 citations

Calcium absorption in the elderly

1975 • 48 citations

Heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor by parathyroid hormone (PTH) and PTH-like peptide in osteoblast-like cells

1988 • 43 citations

Influence of age on effects of endogenous 1,25-dihydroxyvitamin D on calcium absorption in normal women

1994 • 36 citations

Local action of oral 1,25-dihydroxycholecalciferol on calcium absorption in osteoporosis

1987 • 31 citations

RENAL 1,25‐DIHYDROXYVITAMIN D, PHOSPHATURIC, AND CYCLIC‐AMP RESPONSES TO INTRAVENOUS SYNTHETIC HUMAN PARATHYROID HORMONE‐(1‐34) ADMINISTRATION IN NORMAL SUBJECTS

1984 • 10 citations