The Effect of Steroid Hormones on Gene Transcription

DNA Methylation and Gene Function

1980 • 2,069 citations

DNA Modification Mechanisms and Gene Activity During Development

1975 • 1,859 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Cellular differentiation, cytidine analogs and DNA methylation

1980 • 1,803 citations

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.

1979 • 1,532 citations

Repeated Genes in Eukaryotes

1980 • 1,383 citations

The induction of gene activity in drosophila by heat shock

1979 • 1,308 citations

Structure of Chromatin

1977 • 1,276 citations

Solenoidal model for superstructure in chromatin.

1976 • 1,223 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Nucleosome Structure

1980 • 923 citations

Electron microscopic and biochemical evidence that chromatin structure is a repeating unit

1975 • 860 citations

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

1980 • 772 citations

Current Models of Steroid Hormone Action: A Critique

1976 • 707 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

1980 • 634 citations

Temporal Control of Puffing Activity in Polytene Chromosomes

1974 • 632 citations

Supercoiled loops and eucaryotic DNA replication

1980 • 626 citations

Isolation, characterization, and structure of the folded interphase genome of Drosophila melanogaster

1976 • 556 citations

Active chromatin

1982 • 549 citations

Cruciform structures in supercoiled DNA

1981 • 545 citations

Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.

1976 • 523 citations

The inverted repeat as a recognizable structural feature in supercoiled DNA molecules.

1980 • 519 citations

A specific transcription factor that can bind either the 5S RNA gene or 5S RNA.

1980 • 511 citations

Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I

1980 • 486 citations

A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster

1974 • 481 citations

Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

1981 • 475 citations

Split Genes and RNA Splicing

1979 • 467 citations

DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells

1981 • 464 citations

An altered DNA conformation detected by S1 nuclease occurs at specific regions in active chick globin chromatin

1982 • 448 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

Use of restriction enzymes to study eukaryotic DNA methylation

1978 • 442 citations

Adult frogs derived from the nuclei of single somatic cells

1962 • 441 citations

DNAase I-hypersensitive sites of chromatin

1981 • 410 citations

Ovalbumin gene is split in chicken DNA

1977 • 396 citations

Progesterone-binding Components of Chick Oviduct

1971 • 389 citations

The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity

1979 • 389 citations

Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans.

1979 • 383 citations

Specific DNA methylation sites in the vicinity of the chicken β-globin genes

1979 • 365 citations

Major Problems in Developmental Biology

1966 • 364 citations

Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the drosophila genome

1982 • 362 citations

DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes

1979 • 356 citations

Interaction of HMG 14 and 17 with actively transcribed genes

1980 • 355 citations

Primary activation of the vitellogenin gene in the rooster.

1977 • 353 citations

α-globin-gene switching during the development of chicken embryos: Expression and chromosome structure

1981 • 353 citations

Dynamics of Steroid Hormone Receptor Action

1980 • 348 citations

Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones.

1977 • 342 citations

Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

1981 • 341 citations

Isolation of a subclass of nuclear proteins responsible for conferring a DNase I-sensitive structure on globin chromatin.

1979 • 337 citations

Production of mRNA in chinese hamster cells: Relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences

1979 • 326 citations

Estrogen-Induced Uterine Responses and Growth: Relationship to Receptor Estrogen Binding by Uterine Nuclei1¹

1975 • 321 citations

Fractionation of hen oviduct chromatin into transcriptionally active and inactive regions after selective micrococcal nuclease digestion

1978 • 313 citations

The Vertebrate ovary

1978 • 307 citations

Amplification of genes for chorion proteins during oogenesis in Drosophila melanogaster

1980 • 301 citations

Quantitation of parameters that determine the rate of ovalbumin synthesis

1975 • 289 citations

Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action

1975 • 284 citations

Use of restriction enzymes to study eukaryotic DNA methylation

1978 • 281 citations

Growth and Development of Cultured Plant Cells

1964 • 277 citations

H ³ URIDINE INCORPORATION IN LAMPBRUSH CHROMOSOMES

1962 • 259 citations

Chicken oviduct progesterone receptor: Location of specific regions of high-affinity binding in cloned DNA fragments of hormone-responsive genes

1982 • 256 citations

Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA.

1977 • 256 citations

Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors

1978 • 255 citations

A Direct Approach to the Structure of Eukaryotic Chromosomes

1978 • 254 citations

A model for chromatin based upon two symmetrically paired half-nucleosomes

1976 • 245 citations

The Metabolic Code

1975 • 231 citations

Structure and in Vitro Transcription of Human Globin Genes

1980 • 231 citations

The glucocorticoid domain: Steroid-mediated changes in the rate of synthesis of rat hepatoma proteins

1978 • 227 citations

Estrogen Action in Vitro

1972 • 221 citations

Metaphase Chromosome Structure: The Role of Nonhistone Proteins

1978 • 219 citations

Regulated expression of human growth hormone genes in mouse cells

1982 • 219 citations

A significant lag in the induction of ovalbumin messenger RNA by steroid hormones: A receptor translocation hypothesis

1976 • 219 citations

Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes

1980 • 217 citations

Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts

1975 • 215 citations

Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors.

1980 • 208 citations

Vitellogenesis: A Versatile Model for Hormonal Regulation of Gene Expression

1979 • 208 citations

Analysis of DNA of isolated chromatin subunits.

1975 • 202 citations

The induction of ovalbumin and conalbumin mRNA by estrogen and progesterone in chick oviduct explant cultures

1978 • 200 citations

The Origins of Gene Instability in Yeast

1980 • 198 citations

Coordinate regulation of two estrogen-dependent genes in avian liver.

1980 • 190 citations

Hb switching in chickens

1980 • 189 citations

A SIX-HOUR ASSAY FOR THE QUANTITATIVE DETERMINATION OF ESTROGEN1

1938 • 188 citations

Chromomeres and Genes

1972 • 187 citations

Domains in Chromatin Structure

1978 • 186 citations

Acetylation of histone H4 and its role in chromatin structure and function

1980 • 183 citations

Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region

1982 • 181 citations

A subset of trout testis nucleosomes enriched in transcribed DNA sequences contains high mobility group proteins as major structural components.

1979 • 179 citations

The relationship between nuclear receptor·estrogen binding and uterotrophic responses

1972 • 176 citations

Partial Purification of the Template-Active Fraction of Chromatin: A Preliminary Report

1974 • 175 citations

Multiple genes coding for the androgen-regulated major urinary proteins of the mouse

1979 • 174 citations

Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells.

1981 • 174 citations

Regulation of growth hormone gene expression: synergistic effects of thyroid and glucocorticoid hormones.

1977 • 174 citations

Progesterone-binding Protein of Chick Oviduct

1972 • 173 citations

Definition of 5‘ and 3‘ structural boundaries of the chromatin domain containing the ovalbumin multigene family.

1982 • 172 citations

Immunoglobulin Gene Rearrangement in Immature B Cells

1980 • 172 citations

Properties of chromosomal nucleohistone

1963 • 169 citations

Thyroid and glucocorticoid hormones synergistically control growth hormone mRNA in cultured GH1 cells.

1978 • 169 citations

Cloned mouse mammary tumor virus DNA is biologically active in transfected mouse cells and its expression is stimulated by glucocorticoid hormones

1981 • 166 citations

Factors involved in the expression of gene activity in polytene chromosomes

1968 • 166 citations

Ecdysone-stimulated RNA synthesis in imaginal discs of Drosophila melanogaster

1976 • 161 citations

Nucleosome Structure III: The Structure and Transcriptional Activity of the Chromatin Containing the Ovalbumin and Globin Genes in Chick Oviduct Nuclei

1978 • 161 citations

Adenovirus DNA-directed transcription of 5.5S RNA in vitro.

1978 • 160 citations

Endogenous nuclease. Properties and effects on transcribed genes in chromatin.

1982 • 159 citations

Antibodies to estrogen receptor: Immunochemical similarity of estrophilin from various mammalian species

1977 • 156 citations

Electron Microscopic Analysis of Chromosome Metabolism in the Drosophila melanogaster Embryo

1978 • 154 citations

Female Sex Steroids

1979 • 152 citations

Induction of ovalbumin mRNA sequences by estrogen and progesterone in chick oviduct as measured by hybridization to complementary DNA.

1975 • 150 citations

Recombination of Dispersed Repeated DNA Sequences in Yeast

1980 • 149 citations

The ovalbumin gene region: common features in the organisation of three genes expressed in chicken oviduct under hormonal control

1979 • 148 citations

Purified glucocorticoid receptor-hormone complex from rat liver cytosol binds specifically to cloned mouse mammary tumor virus long terminal repeats in vitro.

1982 • 147 citations

Characterization of active transcription units in Balbiani rings of chironomus tentans

1979 • 146 citations

Acetylated histone H4 is preferentially associated with template-active chromatin.

1978 • 146 citations

The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites

1975 • 144 citations

Isolation of actively transcribed nucleosomes using immobilized HMG 14 and 17 and an analysis of α-globin chromatin

1981 • 143 citations

Synthesis of a Deoxyribonucleic Acid Sequence Complementary to Ovalbumin Messenger Ribonucleic Acid and Quantification of Ovalbumin Genes

1973 • 143 citations

Nuclear Receptor—Estrogen Complex: Relationship Between Concentration and Early Uterotrophic Responses1

1973 • 143 citations

Cell Differentiation and Morphogenesis

1967 • 142 citations

Genes transcribed at diverse rates have a similar conformation in chromatin

1977 • 140 citations

Summary: The Molecular Biology of the Eukaryotic Genome Is Coming of Age

1978 • 136 citations

Chromatin fractionation procedure that yields nucleosomes containing near-stoichiometric amounts of high mobility group nonhistone chromosomal proteins

1979 • 136 citations

Effect of estrogen on gene expression in chicken oviduct: Evidence for transcriptional control of ovalbumin gene

1979 • 136 citations

Structural analysis of the fibroin gene at the 5′ end and its surrounding regions

1979 • 136 citations

Kinetics of estrogen induction of Xenopus laevis vitellogenin messenger RNA as measured by hybridization to complementary DNA

1977 • 135 citations

Hormonal inducibility of rat α2u globulin genes in transfected mouse cells

1981 • 131 citations

Sea urchin embryo mRNA sequences expressed in the nuclear RNA of adult tissues

1978 • 131 citations

DNA methylation: correlation with DNase I sensitivity of chicken ovalbumin and conalbumin chromatin

1979 • 130 citations

Tissue-specific exposure of chromatin structure at the 5' terminus of the rat preproinsulin II gene.

1981 • 129 citations

Trophic Interaction between Cloned Tissue Culture Lines of Nerve and Muscle

1971 • 129 citations

Regulation of Gene Expression in the Chick Oviduct by Steroid Hormones

1978 • 129 citations

Temporal Relationships Between Hormone Receptor Binding and Biological Responses inthe Uterus: Studies with Short- and Long-Acting Derivatives of Estriol

1976 • 128 citations

A complex of interacting DNAase I-hypersensitive sites near the drosophila glue protein gene, Sgs4

1982 • 126 citations

Developmental Studies on Giant Chromosomes

1972 • 125 citations

An altered subunit configuration associated with the actively transcribed DNA of integrated adenovirus genes

1977 • 124 citations

Mammary tumor virus DNA contains sequences required for its hormone-regulated transcription

1981 • 120 citations

Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells.

1979 • 120 citations

RNA polymerase activity and uterine growth: differential stimulation by estradiol, estriol, and nafoxidine

1976 • 119 citations

Loss of rDNA methylation accompanies the onset of ribosomal gene activity in early development of X. laevis

1981 • 116 citations

X-Autosome Translocations in The Mouse: Total Inactivation Versus Partial Inactivation Of The X Chromosome

1970 • 115 citations

Localization of ecdysterone on polytene chromosomes of Drosophila melanogaster.

1980 • 115 citations

Chromatin fine structure of active and repressed genes

1981 • 114 citations

Temperature-sensitive changes in the structure of globin chromatin in lines of red cell precursors transformed by ts-AEV

1982 • 110 citations

Properties of active nucleosomes as revealed by HMG 14 and 17 chromatography

1982 • 109 citations

The in vivo methylation of DNA in mouse fibroblasts

1969 • 104 citations

Quantitation of vitellogenin messenger RNA in the liver of male xenopus toads during primary and secondary stimulation by estrogen

1977 • 104 citations

Soluble Complexes between Steroid Hormones and Target-Tissue Receptors Bind Specifically to Target-Tissue Chromatin

1971 • 103 citations

Analysis of chromatin-associated fiber arrays

1976 • 103 citations

Association of the Uterine 17β-Estradiol-Receptor Complex with Ribonucleoprotein in Vitro and in Vivo

1974 • 102 citations

Kinetics of avian vitellogenin messenger RNA induction. Comparison between primary and secondary response to estrogen.

1977 • 102 citations

Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance

1981 • 102 citations

Chromosomal position effects determine transcriptional potential of integrated mammary tumor virus DNA

1982 • 101 citations

Appearance of Vitellogenin mRNA Sequences and Rate of Vitellogenin Synthesis in Chicken Liver following Primary and Secondary Stimulation by 17beta-Estradiol

1978 • 100 citations

mRNA complexity and egg white protein mRNA content in mature and hormone-withdrawn oviduct

1977 • 100 citations

Thyroid hormone nuclear receptor levels are influenced by the acetylation of chromatin-associated proteins.

1980 • 100 citations

Conformation of ovalbumin and globin genes in chromatin during differential gene expression.

1979 • 100 citations

Effect of estrogen on gene expression in the chick oviduct.

1976 • 96 citations

Quantitation of Ovalbumin mRNA in Hen and Chick Oviduct by Hybridization to Complementary DNA

1974 • 96 citations

Steroid Hormone Regulation of Vitellogenin Gene Expressio

1982 • 94 citations

Ecdysone-inducible functions of larval fat bodies in Drosophila

1978 • 94 citations

The Binding of Estradiol-17β to the Bovine Endometrial Nuclear Membrane

1974 • 94 citations

Control of cellular content of chicken egg white protein specific RNA during estrogen administration and withdrawal

1979 • 93 citations

Expression of a chicken chromosomal ovalbumin gene injected into frog oocyte nuclei

1980 • 93 citations

Progesterone-binding components of chick oviduct. Receptor B subunit protein purified to apparent homogeneity from laying hen oviducts.

1977 • 93 citations

Purification and characterization of estrogen-binding proteins from calf uterus. 4. Estrogen-binding proteins of calf uterus. Purification to homogeneity of receptor from cytosol by affinity chromatography

1979 • 93 citations

Multihormonal induction of hepatic α _2u -globulin mRNA as measured by hybridization to complementary DNA

1977 • 92 citations

Monoclonal antibodies against estrogen receptor: interaction with different molecular forms and functions of the receptor

1982 • 92 citations

An abundant androgen-regulated mRNA in the mouse kidney

1979 • 91 citations

Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA

1982 • 90 citations

Estrogen receptors: An evaluation of cytoplasmic-nuclear interactions in a cell-free system and a method for assay

1969 • 88 citations

Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation.

1982 • 88 citations

Nature of Oestrogen Specific Binding Sites in the Nuclei of Mouse Uteri

1971 • 88 citations

Changes in hepatic levels of tyrosine aminotransferase messenger RNA during induction by hydrocortisone.

1978 • 88 citations

Modulation of Ribosomal RNA Synthesis in Oncopeltus fasciatus: An Electron Microscopic Study of the Relationship between Changes in Chromatin Structure and Transcriptional Activity

1978 • 87 citations

The Ovalbumin Gene: Organization, Structure, Transcription, and Regulation

1979 • 85 citations

Hormonal Control of Egg White Protein Messenger RNA Synthesis in the Chicken Oviduct

1978 • 85 citations

Studies on gene control regions XII. The functional significance of a Lac operator constitutive mutation

1979 • 84 citations

Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells

1982 • 83 citations

Rapid accumulation of vitellogenin messenger RNA during secondary estrogen stimulation of Xenopus laevis

1978 • 82 citations

Dynamics of Determination**Dedicated to Karl von Frisch on his eightieth birthday.††Research supported by the Schweizerische Nationalfonds zur Förderung der wissenschaftlichen Forschung.

1966 • 82 citations

Synthesis of [ ³ H]DNA Complementary to Ovalbumin Messenger RNA: Evidence for Limited Copies of the Ovalbumin Gene in Chick Oviduct

1973 • 81 citations

Thyroid Hormone Receptors and Responses

1979 • 81 citations

Hormonal Regulation of Ovalbumin Synthesis in Chick Oviduct

1973 • 80 citations

Transcription by Eukaryotic RNA Polymerases A and B of Chromatin Assembled in vitro

1979 • 80 citations

Genetic Stability and Modulation of Metazoan Nuclei Transplanted into Eggs and Oocytes

1980 • 80 citations

Reconstitution of a deoxyribonuclease I-sensitive structure on active genes.

1980 • 80 citations

Transcription of in vitro assembled chromatin by Escherichia coli RNA polymerase

1979 • 80 citations

A replicative and synthetic chromosomal unit-the modern concept of the chromomere

1966 • 79 citations

Ecdysone-induced changes in morphology and protein synthesis in Drosophila cell cultures

1978 • 79 citations

Multihormonal Regulation of Casein Gene Expression at the Transcriptional and Posttranscriptional Levels in the Mammary Gland

1980 • 78 citations

Specific interactions of Saccharomyces cerevisiae proteins with a promoter region of eukaryotic tRNA genes.

1982 • 75 citations

Classification of loops of lampbrush chromosomes according to the arrangement of transcriptional complexes

1976 • 74 citations

Effect of estrogen on gene expression in the chick oviduct. Correlation between nuclear-bound estrogen receptor and chromatin initiation site for transcription.

1976 • 73 citations

The Generation and Propagation of Variegated Chromosome Structures

1978 • 72 citations

Morphology of Transcriptionally Active Chromatin

1978 • 72 citations

Regulation of gene expression in the chick oviduct. 18. Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene

1978 • 71 citations

Deoxyribonuclease I sensitivity of the nontranscribed sequences flanking the 5' and 3' ends of the ovomucoid gene and the ovalbumin and its related X and Y genes in hen oviduct nuclei

1980 • 71 citations

The structure of chromatin as revealed by deoxyribonuclease digestion studies

1972 • 70 citations

Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes.

1979 • 69 citations

Von der Ecdysonkonzentration abhängige Genaktivitätsmuster in den Speicheldrüsenchromosomen von Chironomus tentans

1963 • 68 citations

Segregation of rapidly acetylated histones into a chromatin fraction released from intact nuclei by the action of micrococcal nuclease

1980 • 67 citations

Distribution of messenger RNA-coding sequences in fractionated chromatin

1977 • 67 citations

Isolation of two closely related vitellogenin genes, including their flanking regions, from a Xenopus laevis gene library.

1980 • 66 citations

The length of nucleosome-associated DNA is the same in both transcribed and nontranscribed regions of chromatin

1978 • 65 citations

Application of recombinant DNA technology to questions of developmental biology: A review

1979 • 65 citations

Size, Complexity and Abundance of a Specific Poly(A)‐Containing RNA of Liver from Male Xenopus Induced to Vitellogenin Synthesis by Estrogen

1976 • 64 citations

Evidence for two kinds of chromatin binding sites for the estradiol-receptor complex

1978 • 64 citations

Glucocorticoid induction of hepatic alpha2u-globulin synthesis and messenger RNA level in castrated male rats in vivo

1978 • 63 citations

The structure of the thymidine kinase gene promoter: Nuclease hypersensitivity correlates with expression

1982 • 63 citations

Localization of histone gene transcripts in newt lampbrush chromosomes by in situ hybridization

1977 • 63 citations

An antiserum to the rat liver glucocorticoid receptor.

1980 • 63 citations

Isolation of glucocorticoid-unresponsive rat hepatoma cells by fluorescence-activated cell sorting

1980 • 63 citations

Definition of the 5′ and 3′ ends of transcripts of the ovalbumin gene

1980 • 62 citations

Bioassay for components regulating eukaryotic gene expression: a chromosomal factor involved in the generation of histone mRNA 3' termini.

1982 • 62 citations

Developmental studies on giant chromosomes

1974 • 61 citations

alpha-Fetoprotein and albumin genes of rats: no evidence for amplification-deletion or rearrangement in rat liver carcinogenesis.

1979 • 60 citations

Effect of estrogen on preprolactin messenger ribonucleic acid sequences

1979 • 60 citations

Selective binding of chicken progesterone receptor a subunit to a DNA fragment containing ovalbumin gene sequences

1982 • 59 citations

DNA methylation in chicken alpha-globin gene expression.

1982 • 58 citations

Partial inhibition of histone deacetylase in active chromatin by HMG 14 and HMG 17

1980 • 58 citations

An Insoluble Receptor for Oestrogens in the “Residual” Nuclear Proteins of Chick‐Liver

1973 • 57 citations

Hormonal regulation of the conformation of the ovalbumin gene in chick oviduct chromatin.

1982 • 55 citations

Interaction of the estradiol receptor from calf uterus with its nuclear acceptor sites

1975 • 55 citations

Factors affecting the binding of chick oviduct progesterone receptor to deoxyribonucleic acid: evidence that deoxyribonucleic acid alone is not the nuclear acceptor site

1980 • 54 citations

Nucleosomal packaging of the thymidine kinase gene of herpes simplex virus transferred into mouse cells: an actively expressed single-copy gene.

1980 • 53 citations

Eucaryotic gene regulation

1979 • 53 citations

Late modifications of simian virus 40 chromatin during the lytic cycle occur in an immature form of virion

1980 • 52 citations

Chromosomes Isolated from Unfixed Salivary Glands of Chironomus

1972 • 52 citations

Selective displacement of histone H1 from whole HeLa nuclei: effect on chromatin structure in situ as probed by micrococcal nuclease

1979 • 51 citations

Putative androgen receptors distinguished in wild-type and testicular-feminized (Tfm) mice

1979 • 51 citations

The One Band-One Gene Hypothesis: Evidence from a Cytogenetic Analysis of Mutant and Nonmutant Rearrangement Breakpoints in Drosophila Melanogaster

1974 • 50 citations

Gene Regulation by Steroid Hormones II

1983 • 50 citations

Histone acetylation and hormone action. Early effects of oestradiol-17β on histone acetylation in rat uterus

1972 • 49 citations

Dexamethasone inhibits α-fetoprotein gene expression in developing mouse liver

1979 • 49 citations

Heterogeneity of Estrogen Binding Sites: Relationship to Estrogen Receptors and Estrogen Responses

1980 • 48 citations

mRNA STABILITY AND CELLULAR DIFFERENTIATION

1972 • 46 citations

Corrected splicing of a chicken ovalbumin gene transcript in mouse L cells.

1980 • 46 citations

Thyroid Hormone Receptor-Containing Fragment Released from Chromatin by Deoxyribonuclease I and Micrococcal Nuclease

1980 • 45 citations

Enrichment of estradiol-receptor complexes in a transcriptionally active fraction of chromatin from MCF-7 cells

1980 • 45 citations

Interaction of the chick oviduct progesterone receptor with deoxyribonucleic acid

1981 • 44 citations

Commitment of chick oviduct tubular gland cells to produce ovalbumin mRNA during hormonal withdrawal and restimulation.

1980 • 44 citations

Chromatin structure, DNA structure

1982 • 44 citations

Role of nuclear proteins as high affinity sites (“acceptors”) for progesterone in the avian oviduct

1976 • 43 citations

Structure of Xenopus Ribosomal Gene Chromatin during Changes in Genomic Transcription Rates

1978 • 43 citations

Different Nucleosome Structures on Transcribing and Nontranscribing Ribosomal Gene Sequences

1979 • 42 citations

Evaluating the contribution of posttranscriptional processing to differential gene expression

1979 • 42 citations

Ecdysone-stimulated RNA synthesis in salivary glands of drosophila melanogaster: Assay by in situ hybridization

1977 • 42 citations

Primary induction of vitellogenin mRNA in the rooster by 17beta-estradiol.

1978 • 41 citations

Differential hormonal responsiveness of the ovalbumin gene and its pseudogenes in the chick oviduct

1980 • 41 citations

Hormonal Domains of Response: Actions of Glucocorticoid and Thyroid Hormones in Regulating Pleiotropic Responses in Cultured Cells

1980 • 41 citations

Synthesis and Degradation of Glucose-6-Phosphate Dehydrogenase in the Rat Uterus

1971 • 39 citations

Estrogen receptor in hen oviduct chromatin, digested by micrococcal nuclease

1978 • 37 citations

The switch region associated with immunoglobulin Cμ genes is DNase I hypersensitive in T lymphocytes

1981 • 36 citations

Hemoglobin switching in sheep: Only the γ gene is in the active conformation in fetal liver but all the β and γ genes are in the active conformation in bone marrow

1978 • 34 citations

Glucocorticoid modulation of casein gene transcription in mouse mammary gland.

1979 • 34 citations

RNA transcription and uterine growth: differential effects of estradiol, estriol, and nafoxidine on chromatin RNA initiation sites

1978 • 34 citations

Gene Activity Patterns and Cellular Differentiation

1966 • 33 citations

Nuclear estrogen receptor in the avian liver: Correlation with biologic response

1978 • 32 citations

Intracellular forms of simian virus 40 nucleoprotein complexes. III. Study of histone modifications

1980 • 31 citations

Studies on the Mechanism of Transcription of Nucleosomal Complexes

1980 • 30 citations

Chromatin structure of the ovalbumin gene family in the chicken oviduct

1983 • 29 citations

A correlation between nucleosome spacer region susceptibility to DNase 1 and histone acetylation

1979 • 29 citations

Stilbestrols and stilbestrol derivatives: Estrogenic potency and temporal relationships between estrogen receptor binding and uterine growth

1978 • 28 citations

Mammary Tumor Virus DNA: A Glucocorticoid-responsive Transposable Element

1978 • 28 citations

The release of high mobility group protein H6 and protamine gene sequences upon selective DNase I degradation of trout testis chromatin

1980 • 28 citations

Nuclease sensitivity and DNA methylation in estrogen regulation of Xenopus laevis vitellogenin gene expression.

1983 • 27 citations

Histone acetylation and hormone action. Early effects of aldosterone on histone acetylation in rat kidney

1973 • 27 citations

Distribution Patterns of Drosophila Nonhistone Chromosomal Proteins

1978 • 26 citations

Glucocorticoid Receptor Cleavage by Leupeptin-Sensitive Enzymes in Rat Kidney Cytosol

1979 • 26 citations

Enzymatic DNA modifications in isolated nuclei from developing sea urchin embryos

1972 • 25 citations

The transcript from a DNA puff of Rhynchosciara and its migration to the cytoplasm

1979 • 25 citations

An assessment of the ecdysteroid receptor of drosophila

1982 • 24 citations

Nucleosome Structure, DNA Folding, and Gene Activity

1978 • 24 citations

Active chromatin of oocytes injected with somatic cell nuclei or cloned DNA

1982 • 24 citations

"Native" Salivary Chromosomes of Drosophila melanogaster

1978 • 24 citations

The Two-dimensional Fractionation of Drosophila DNA

1978 • 23 citations

Postsynthetic Modifications of Histone Primary Structure: Phosphorylation and Acetylation as Related to Chromatin Conformation and Function

1978 • 23 citations

Structurally altered and transcriptionally activated rat prostate chromatin induced by androgens

1977 • 22 citations

A quantitative electron-microscope analysis of chromatin from Xenopus laevis lampbrush chromosomes

1979 • 22 citations

Effect of Cibacron blue F3GA on oligonucleotide binding site of estradiol--receptor complexes of mouse uterine cytosol.

1979 • 22 citations

Transcription in Giant Chromosomal Puffs

1972 • 22 citations

Fate of Balbiani-ring RNA In Vivo

1978 • 21 citations

Functional Organization of Polytene Chromosomes

1978 • 21 citations

The transcription of eukaryotic genes

1980 • 21 citations

The time during which β-ecdysone is required for the differentiation in vitro and in situ of wing imaginal discs of Drosophila melanogaster

1977 • 20 citations

Escherichia coli RNA polymerase in vitro mimics simian virus 40 in vivo transcription when the template is viral nucleoprotein.

1980 • 19 citations

Accessibility of the ribosomal genes to micrococcal nuclease in Physarum polycephalum

1979 • 18 citations

Estrogen withdrawal in chick oviduct

1978 • 18 citations

Distribution of estrogen receptors in hen oviduct chromatin fractions in the course of DNAase II digestion

1977 • 15 citations

Simian virus 40 maturation: chromatin modifications increase the accessibility of viral DNA to nuclease and RNA polymerase

1981 • 15 citations

The Size and Chromosomal Location of the 75S RNA Transcription Unit in Balbiani Ring 2

1978 • 14 citations

Specificity of oligodeoxynucleotide binding of mouse uterine cytosol estradiol receptors.

1980 • 13 citations

Protein synthetic patterns during differentiation of imaginal discs in vitro

1978 • 13 citations

Hypothalamic Progestin Receptors: Evidence for Two Classes of High Affinity Binding Sites*

1983 • 12 citations

Nuclear proteins in Drosophila melanogaster cells after heat shock and their binding to homologous DNA

1980 • 12 citations

Accurate transcription of simian virus 40 chromatin in a HeLa cell extract

1982 • 12 citations

Polytene Chromosomes in Studies of Gene Expression

1974 • 11 citations

The extraction by micrococcal nuclease of ghucocorticoid receptors and mouse mammary tumor virus DNA sequences is dissociated

1980 • 11 citations

The Specific Binding of Estradiol to the Nuclear Matrix

1979 • 9 citations

The high mobility group proteins and transcribed nucleosomes

1981 • 9 citations

Hormonal Modulation of 2u Globulin mRNA: Sequence Measurements Using a Specific cDNA Probe

1978 • 9 citations

The IN VITRO Transcription of Xenopus 5S DNA

1979 • 8 citations

FACTORS INVOLVED IN THE TRANSCRIPTION OF PURIFIED GENES BY RNA POLYMERASE III

1979 • 8 citations

Biochemical actions of hormones, vol. 5

1979 • 8 citations

Structural Relationships between the Chick Oviduct Progesterone Receptor A and B Proteins

1979 • 7 citations

Histone acetylation and hormone action

1974 • 6 citations

The Immunoendocrinology of Estrophilin

1979 • 5 citations

Estrogen withdrawal in chick oviduct. Evidence for continued expression of active unique genes using an "expressed" DNA probe

1979 • 3 citations

Hormonal regulation of cloned genes

1981 • 2 citations

Effects of Steroid Hormones on Chicken Oviduct Chromatin

1983 • 2 citations

STRUCTURE AND EXPRESSION OF OVALBUMIN AND CLOSELY RELATED CHICKEN GENES

1979 • 2 citations