Detection of the interleukin 18 family in rat brain by RT-PCR

Cloning of a new cytokine that induces IFN-γ production by T cells

1995 • 2,584 citations

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

1997 • 1,172 citations

Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

1997 • 1,137 citations

Cytokines and the nervous system II: actions and mechanisms of action

1995 • 928 citations

Interleukin-18 Binding Protein

1999 • 759 citations

Differential Cytokine and Chemokine Gene Expression by Human NK Cells Following Activation with IL-18 or IL-15 in Combination with IL-12: Implications for the Innate Immune Response

1999 • 644 citations

Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.

1996 • 635 citations

Purification and Characterization of the Human Interleukin-18 Receptor

1997 • 471 citations

Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation

1997 • 381 citations

Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling

1998 • 326 citations

IL-18 accounts for both TNF-alpha- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice.

1997 • 325 citations

Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development

1998 • 289 citations

IL-1Rrp Is a Novel Receptor-like Molecule Similar to the Type I Interleukin-1 Receptor and Its Homologues T1/ST2 and IL-1R AcP

1996 • 225 citations

Identification of alpha 2-macroglobulin as a carrier protein for IL-6.

1989 • 208 citations

Interleukin-18 Activates NF-κB in Murine T Helper Type 1 Cells

1997 • 192 citations

Cultures of astrocytes and microglia express interleukin 18

1999 • 184 citations

Induction of Interferon-γ Inducing Factor in the Adrenal Cortex

1997 • 156 citations

Murine Microglial Cells Produce and Respond to Interleukin‐18

1999 • 153 citations

Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitis.

1998 • 147 citations

Cloning and expression of interleukin‐18 binding protein

1999 • 122 citations

Binding of Interleukin-18 to the Interleukin-1 Receptor Homologous Receptor IL-1Rrp1 Leads to Activation of Signaling Pathways Similar to Those Used by Interleukin-1

1998 • 118 citations

Neutralizing Antibodies to IFN-γ-Inducing Factor Prevent Experimental Autoimmune Encephalomyelitis

1998 • 117 citations

Cloning of rat brain interleukin-18 cDNA

1998 • 92 citations

Interferon-γ–inducing factor (IL-18) and interferon-γ in inflammatory CNS diseases

1999 • 73 citations

Interleukin-18 Induces Activation and Association of p56lck and MAPK in a Murine TH1 Clone

1997 • 53 citations

QUANTIFICATION OF HUMAN INTERLEUKIN 18 mRNA EXPRESSION BY COMPETITIVE REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION

1999 • 23 citations