Regulation of putative muscarinic cholinergic receptor subtypes in rat brain

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A rapid radiochemical method for the determination of choline acetyltransferase

1975 • 2,406 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

1980 • 1,579 citations

Pirenzepine distinguishes between different subclasses of muscarinic receptors

1980 • 1,299 citations

Statistical Quality Control and Routine Data Processing for Radioimmunoassays and Immunoradiometric Assays

1974 • 1,063 citations

Muscarinic receptor subtypes: M1 and M2 biochemical and functional characterization

1982 • 699 citations

Loss of M2 Muscarine Receptors in the Cerebral Cortex in Alzheimer's Disease and Experimental Cholinergic Denervation

1985 • 697 citations

Beta-adrenergic receptors: biochemical mechanisms of physiological regulation

1984 • 672 citations

The binding of agonists to brain muscarinic receptors.

1978 • 656 citations

Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting

1972 • 615 citations

The Classification of Dopamine Receptors: Relationship to Radioligand Binding

1983 • 392 citations

Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain.

1984 • 312 citations

A unique regulatory profile and regional distribution of [3H]pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes

1983 • 298 citations

Receptor Adaptations to Centrally Acting Drugs

1981 • 293 citations

Statistical characterization of the random errors in the radioimmunoassay dose--response variable.

1976 • 244 citations

Muscarinic receptor subclasses

1983 • 238 citations

Agonists differentiate muscarinic receptors that inhibit cyclic AMP formation from those that stimulate phosphoinositide metabolism.

1984 • 219 citations

Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase.

1985 • 217 citations

The effect of cholinergic drugs on [3H]acetylcholine release from slices of rat hippocampus, striatum and cortex

1977 • 191 citations

The character of the muscarinic receptors in different regions of the rat brain

1980 • 188 citations

[3H] pirenzepine selectively identifies a high affinity population of muscarinic cholinergic receptors in the rat cerebral cortex

1982 • 184 citations

Postsynaptic localization of muscarinic cholinergic receptor binding in rat hippocampus

1974 • 179 citations

Regulation of neocortical muscarinic receptors: effects of drug treatment and lesions

1982 • 155 citations

Muscarinic antagonist binding site heterogeneity as evidenced by autoradiography after direct labeling with [3H]-QNB and [3H]-pirenzepine

1984 • 148 citations

Muscarinic autoreceptor regulates acetylcholine release in rat hippocampus: in vitro evidence

1980 • 144 citations

Comparison of [3H]pirenzepine and [3H]quinuclidinylbenzilate binding to muscarinic cholinergic receptors in rat brain.

1984 • 137 citations

Adenylate cyclase activity of synaptic membranes from rat striatum. Inhibition by muscarinic receptor agonists.

1983 • 134 citations

Muscarinic supersensitivity induced by septal lesion or chronic atropine treatment

1981 • 132 citations

Release of [3H]acetylcholine from rat hippocampal slices: Effect of septal lesion and of graded concentrations of muscarinic agonists and antagonists

1977 • 116 citations

Autoregulation of acetylcholine release in isolated hippocampal nerve endings

1981 • 102 citations

Muscarinic receptor binding in mouse brain: Regulation by guanine nucleotides

1980 • 90 citations

Guanyl Nucleotide and Divalent Cation Regulation of Cortical S₂ Serotonin Receptors

1984 • 82 citations

Guanine nucleotide-sensitive, high affinity binding of carbachol to muscarinic cholinergic receptors of 1321N1 astrocytoma cells is insensitive to pertussis toxin.

1985 • 78 citations

Regulation of muscarinic agonist binding by cations and guanine nucleotides

1983 • 73 citations

The influence of guanyl-5′-yl imidodiphosphate and sodium on muscarinic receptor binding in the rat brain and longitudinal muscle of the rat ileum

1980 • 71 citations

Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism

1985 • 63 citations

Regulation of muscarinic receptor binding by guanine nucleotides and N‐ethylmaleimide

1980 • 62 citations

N-Ethylmaleimide-induced alteration in the interaction of agonists with muscarinic cholinergic receptors of rat brain.

1983 • 53 citations

Failure of septal lesions to alter muscarinic cholinergic or benzodiazepine binding sites in hippocampus of rat brain

1980 • 49 citations

Agonist binding to multiple muscarinic receptors.

1984 • 46 citations

DOES PIRENZEPINE DISTINGUISH BETWEEN ‘SUBTYPES’ OF MUSCARINIC RECEPTORS?

1982 • 43 citations

Differential regulation of high-affinity agonist binding to muscarinic sites in the rat heart, cerebellum, and cerebral cortex

1983 • 26 citations

Septal deafferentation increases hippocampal adrenergic receptors: correlation with sympathetic axon sprouting.

1983 • 21 citations

Muscarinic receptor: multiple sites or unitary concept?

1981 • 10 citations