Acute and Chronic Nicotine Exposures Modulate the Immune System through Different Pathways

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Further improvements in the plaque technique for detecting single antibody-forming cells.

1968 • 2,171 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

Calcium signaling

1995 • 1,905 citations

Inositol Trisphosphate and Calcium Signaling

1995 • 1,036 citations

Altered Peptide Ligand–Induced Partial T Cell Activation: Molecular Mechanisms and Role in T Cell Biology

1996 • 698 citations

Immunotoxicology and immunopharmacology

1986 • 428 citations

Immunotoxicology and immunopharmacology

1995 • 253 citations

Effects of nicotine on the immune response. II. Chronic nicotine treatment induces T cell anergy.

1996 • 212 citations

Neuronal nicotinic receptors : pharmacology and therapeutic opportunities

1999 • 203 citations

Effects of cigarette smoke on immune response: chronic exposure to cigarette smoke impairs antigen-mediated signaling in T cells and depletes IP3-sensitive Ca(2+) stores.

2000 • 201 citations

Effects of Mainstream and Environmental Tobacco Smoke on the Immune System in Animals and Humans: A Review

1990 • 191 citations

Environmentally induced changes in immunological function: acute and chronic effects of inhalation of tobacco smoke and other atmospheric contaminants in man and experimental animals

1977 • 182 citations

Effects of Nicotine on the Immune Response. I. Chronic Exposure to Nicotine Impairs Antigen Receptor-Mediated Signal Transduction in Lymphocytes

1995 • 155 citations

Novel mechanism for inhibition of human T cells by glucocorticoids. Glucocorticoids inhibit signal transduction through IL-2 receptor.

1993 • 151 citations

Chemical constituents and bioactivity of tobacco smoke.

1986 • 139 citations

Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways.

1994 • 133 citations

Effect of nicotine on the immune system: Possible regulation of immune responses by central and peripheral mechanisms

1998 • 126 citations

Nicotinic receptors in the brain

1996 • 120 citations

Pituitary hormone response to cigarette smoking

1986 • 101 citations

Close association of IgA anti-ganglioside antibodies with antecedent Campylobacter jejuni infection in Guillain–Barré and Fisher's syndromes

1998 • 98 citations

Nicotine elevates rat plasma ACTH by a central mechanism.

1987 • 87 citations

Nicotine-Induced Modulation of T Cell Function

1998 • 86 citations

Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.

1997 • 55 citations

The effects of morphine, nicotine and epibatidine on lymphocyte activity and hypothalamic-pituitary-adrenal axis responses.

1999 • 51 citations

Cigarette smoke causes inhibition of the immune response to intratracheally administered antigens

1989 • 48 citations

Intracellular calcium signaling induced by thapsigargin in excitable and inexcitable cells

1994 • 41 citations

Early mobilization of Ca2+ is not required for glucocorticoid-induced apoptosis in thymocytes.

1993 • 39 citations

Developmental Neurotoxicity of Nicotine, Carbon Monoxide, and Other Tobacco Smoke Constituents

1989 • 37 citations

EVIDENCE THAT GLUCOCORTICOSTEROID-MEDIATED IMMUNOSUPPRESSIVE EFFECTS DO NOT INVOLVE ALTERING SECOND MESSENGER FUNCTION

1991 • 28 citations

Nicotine suppresses the proliferative response of peripheral blood lymphocytes in rats

1992 • 13 citations

Immunological effects of acute and chronic nicotine administration in rats

1994 • 8 citations