Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Predicting Coiled Coils from Protein Sequences

1991 • 3,977 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

A simple and efficient method for direct gene deletion inSaccharomyces cerevisiae

1993 • 1,256 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

Feedback control of mitosis in budding yeast

1991 • 1,167 citations

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

1991 • 1,125 citations

Isolation of a Miller–Dicker lissencephaly gene containing G protein β-subunit-like repeats

1993 • 1,067 citations

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1995 • 940 citations

Mitotic spindle organization by a plus-end-directed microtubule motor

1992 • 643 citations

XKCM1: A Xenopus Kinesin-Related Protein That Regulates Microtubule Dynamics during Mitotic Spindle Assembly

1996 • 539 citations

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.

1995 • 466 citations

The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.

1996 • 422 citations

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans

1990 • 404 citations

Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

1992 • 401 citations

Disruption of mitotic spindle orientation in a yeast dynein mutant.

1993 • 392 citations

Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae.

1995 • 384 citations

Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13

1993 • 376 citations

Kinesin-related proteins required for structural integrity of the mitotic spindle

1992 • 374 citations

Cytoplasmic dynein is required for normal nuclear segregation in yeast.

1993 • 373 citations

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene

1990 • 366 citations

A bipolar kinesin

1996 • 365 citations

Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans.

1994 • 352 citations

Kinesin-related proteins required for assembly of the mitotic spindle.

1992 • 347 citations

NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.

1995 • 337 citations

Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae.

1992 • 308 citations

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1).

1995 • 307 citations

Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.

1993 • 301 citations

Cytoplasmic dynein and actin-related protein Arp1 are required for normal nuclear distribution in filamentous fungi.

1994 • 300 citations

The kinesin-like protein KLP61F is essential for mitosis in Drosophila.

1993 • 299 citations

Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends.

1994 • 271 citations

Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation.

1994 • 271 citations

Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle.

1995 • 269 citations

Kinesin-related cut 7 protein associates with mitotic and meiotic spindles in fission yeast

1992 • 262 citations

Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast.

1995 • 235 citations

Synthetic enhancement in gene interaction: a genetic tool come of age

1993 • 234 citations

The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.

1994 • 231 citations

A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration

1994 • 223 citations

Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation.

1995 • 209 citations

A “slow” homotetrameric kinesin-related motor protein purified from Drosophila embryos.

1994 • 183 citations

Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes.

1990 • 182 citations

GENETIC ANALYSIS OF THE YEAST CYTOSKELETON

1987 • 179 citations

BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin.

1990 • 178 citations

Going mobile: microtubule motors and chromosome segregation.

1996 • 175 citations

Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae.

1992 • 171 citations

The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly.

1995 • 165 citations

Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase.

1995 • 159 citations

Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function.

1990 • 157 citations

Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function.

1992 • 120 citations

Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product.

1996 • 120 citations

Migration of neuroblasts by perikaryal translocation: Role of cellular elongation and axonal outgrowth in the acoustic nuclei of the chick embryo medulla

1990 • 117 citations

Yeast Num1p associates with the mother cell cortex during S/G2 phase and affects microtubular functions.

1995 • 115 citations

Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations.

1993 • 108 citations

ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle.

1994 • 101 citations

p150Glued, the largest subunit of the dynactin complex, is nonessential in Neurospora but required for nuclear distribution.

1996 • 98 citations

The JNM1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle.

1994 • 95 citations

Nuclear migration advances in fungi

1995 • 93 citations

GENETIC ANALYSIS OF THE MITOTIC SPINDLE

1996 • 82 citations

Type 1 Protein Phosphatase Acts in Opposition to Ipll Protein Kinase in Regulating Yeast Chromosome Segregation

1994 • 73 citations

Nuclear migration in Saccbaromyces cerevisiae is controlled by the highly repetitive 313 kDa NUM1 protein

1991 • 70 citations

The Saccharomyces cerevisiae Checkpoint Gene BUB1 Encodes a Novel Protein Kinase

1994 • 69 citations

Cellular roles of kinesin and related proteins

1994 • 67 citations

Chromosome Instability Mutants of Saccharomyces cerevisiae That Are Defective in Microtubule-Mediated Processes

1990 • 59 citations

Novel forms of neuronal migration in the rat cerebellum

1995 • 58 citations

Sequence homologies between four cytoskeleton-associated proteins

1993 • 53 citations

Direct observation in vitro of how neuroblasts migrate: Medulla and cochleovestibular ganglion of the chick embryo

1991 • 44 citations

RPK1, an essential yeast protein kinase involved in the regulation of the onset of mitosis, shows homology to mammalian dual-specificity kinases

1994 • 36 citations