Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of a Single-Dose of NN2211, a Long-Acting Glucagon-Like Peptide 1 Derivative, in Healthy Male Subjects
Data up to Jan 2025
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Abstract
References (26)
GLUCAGON-LIKE PEPTIDE-1 7-36: A PHYSIOLOGICAL INCRETIN IN MAN
1987 • 1,845 citations
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in Type 2 (non-insulin-dependent) diabetic patients
1993 • 1,064 citations
The Glucagon-Like Peptides
1999 • 1,018 citations
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
1997 • 799 citations
Truncated GLP-1 (proglucagon 78?107-amide) inhibits gastric and pancreatic functions in man
1993 • 661 citations
Potent Derivatives of Glucagon-like Peptide-1 with Pharmacokinetic Properties Suitable for Once Daily Administration
2000 • 644 citations
Glucagon-like peptide-1: a potent regulator of food intake in humans
1999 • 564 citations
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
1999 • 516 citations
The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
2002 • 498 citations
Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men.
1999 • 454 citations
Minireview: The Glucagon-Like Peptides
2001 • 393 citations
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.
1999 • 335 citations
Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo
1995 • 313 citations
Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men
1998 • 298 citations
Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?
2000 • 292 citations
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM
1996 • 286 citations
Insulinotropic Action of Glucagonlike Peptide-I-(7–37) in Diabetic and Nondiabetic Subjects
1992 • 282 citations
Bedtime Administration of NN2211, a Long-Acting GLP-1 Derivative, Substantially Reduces Fasting and Postprandial Glycemia in Type 2 Diabetes
2002 • 269 citations
Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs
1996 • 225 citations
Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7?36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships
1995 • 199 citations
Glucagon-Like Peptide-1 Infusion Must Be Maintained for 24 h/day to Obtain Acceptable Glycemia in Type 2 Diabetic Patients Who Are Poorly Controlled on Sulphonylurea Treatment
2001 • 172 citations
Initiation of Increased Pancreatic Islet Growth in Young Normoglycemic Mice (Umeå +/?)*
1999 • 153 citations
Subcutaneous Injection of the Incretin Hormone Glucagon-Like Peptide 1 Abolishes Postprandial Glycemia in NIDDM
1994 • 138 citations
Insulinotropic actions of intravenous glucagon-like peptide-1 (GLP-1) [7?36 amide] in the fasting state in healthy subjects
1995 • 101 citations
A Radioimmunoassay for LY315902 an analog of Glucagon-like Insulinotropic Peptide, and Its Application in the Study of Canine Pharmacokinetics
1997 • 18 citations
Effect of the protracted GLP-1 derivative NN2211 in betacell reduced minipig
2000 • 1 citations